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1985 1
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2007 20
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1,702 results

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Page 1
ACTB in cancer.
Guo C, Liu S, Wang J, Sun MZ, Greenaway FT. Guo C, et al. Clin Chim Acta. 2013 Feb 18;417:39-44. doi: 10.1016/j.cca.2012.12.012. Epub 2012 Dec 22. Clin Chim Acta. 2013. PMID: 23266771 Review.
However, ACTB is closely associated with a variety of cancers and accumulating evidence indicates that ACTB is de-regulated in liver, melanoma, renal, colorectal, gastric, pancreatic, esophageal, lung, breast, prostate, ovarian cancers, leukemia and lymphoma. ACT
However, ACTB is closely associated with a variety of cancers and accumulating evidence indicates that ACTB is de-regulated in …
A pan-cancer analysis of the prognostic and immunological role of beta-actin (ACTB) in human cancers.
Gu Y, Tang S, Wang Z, Cai L, Lian H, Shen Y, Zhou Y. Gu Y, et al. Bioengineered. 2021 Dec;12(1):6166-6185. doi: 10.1080/21655979.2021.1973220. Bioengineered. 2021. PMID: 34486492 Free PMC article.
Differential expression of ACTB was found between cancer and adjacent normal tissues, and significant associations was found between ACTB expression and prognosis of tumor patients. ...Our first pan-cancer study of ACTB offers insight into the prognostic and …
Differential expression of ACTB was found between cancer and adjacent normal tissues, and significant associations was found between …
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relevance for real-time quantitative PCR.
Bednarz-Misa I, Neubauer K, Zacharska E, Kapturkiewicz B, Krzystek-Korpacka M. Bednarz-Misa I, et al. Adv Clin Exp Med. 2020 May;29(5):547-556. doi: 10.17219/acem/118845. Adv Clin Exp Med. 2020. PMID: 32424999 Free article.
ACTB, B2M and GAPDH correlated with circulating inflammatory/angiogenic indices, differently in IBD and CRC. CONCLUSIONS: Leukocyte GAPDH, ACTB, and B2M expression is affected by bowel inflammation and cancer, rendering them unsuitable as a reference in CRC and IBD.
ACTB, B2M and GAPDH correlated with circulating inflammatory/angiogenic indices, differently in IBD and CRC. CONCLUSIONS: Leukocyte G
GLI1-Altered Mesenchymal Tumors With ACTB or PTCH1 Fusion: A Molecular and Clinicopathologic Analysis.
Kerr DA, Cloutier JM, Margolis M, Mata DA, Rodrigues Simoes NJ, Faquin WC, Dias-Santagata D, Chopra S, Charville GW, Wangsiricharoen S, Lazar AJ, Wang WL, Rosenberg AE, Tse JY. Kerr DA, et al. Mod Pathol. 2024 Feb;37(2):100386. doi: 10.1016/j.modpat.2023.100386. Epub 2023 Nov 20. Mod Pathol. 2024. PMID: 37992966
A subset was stained with S100 protein (n = 7/13), SMA (n = 6/13), keratin (n = 2/9), EMA (n = 3/7), and CD99 (n = 2/6). Tumors harbored ACTB::GLI1 (n = 15) or PTCH1::GLI1 (n = 1) fusions. The assays used did not capture cases defined by GLI1 amplification. ...
A subset was stained with S100 protein (n = 7/13), SMA (n = 6/13), keratin (n = 2/9), EMA (n = 3/7), and CD99 (n = 2/6). Tumors harbored …
ACTB Mutations Analysis and Genotype-Phenotype Correlation in Becker's Nevus.
Dai S, Wang H, Lin Z. Dai S, et al. Biomedicines. 2021 Dec 10;9(12):1879. doi: 10.3390/biomedicines9121879. Biomedicines. 2021. PMID: 34944694 Free PMC article.
Recent studies have revealed that BN patients harbored postzygotic ACTB mutations, which were restricted to arrector pili muscle lineage. We screened for ACTB mutations in 20 Chinese patients with BN and found that recurrent mutations (c.C439A or c.C439T) in ACTB
Recent studies have revealed that BN patients harbored postzygotic ACTB mutations, which were restricted to arrector pili muscle line …
ACTB may serve as a predictive marker for the efficacy of lenvatinib in patients with HBV-related early-stage hepatocellular carcinoma following partial hepatectomy: a retrospective cohort study.
Dong W, Zou M, Sheng J, Zhou W, Wang Y, Zhang Y, Li J, Qian Y, Yu H, Lu T, Pan J, Zhu Y, Qu S, Yang Z, Lin Q, Zhao L, Cong W, Xu B, Zhang C, Liu H, Dong H. Dong W, et al. J Gastrointest Oncol. 2023 Dec 31;14(6):2479-2499. doi: 10.21037/jgo-23-942. Epub 2023 Dec 27. J Gastrointest Oncol. 2023. PMID: 38196518 Free PMC article.
The X-Tile was employed to determine the optimal cut-off point of ACTB levels for predicting time to recurrence (TTR). To assess the correlation between ACTB levels and lenvatinib efficacy, a subgroup analysis of TTR was conducted. ...Moreover, the PDXs derived from …
The X-Tile was employed to determine the optimal cut-off point of ACTB levels for predicting time to recurrence (TTR). To assess the …
Post-zygotic ACTB mutations underlie congenital smooth muscle hamartomas.
Atzmony L, Ugwu N, Zaki TD, Antaya RJ, Choate KA. Atzmony L, et al. J Cutan Pathol. 2020 Aug;47(8):681-685. doi: 10.1111/cup.13683. Epub 2020 Apr 6. J Cutan Pathol. 2020. PMID: 32170967 Free PMC article.
BACKGROUND: Congenital smooth muscle hamartomas (CSMHs) are benign lesions that share clinical and histopathological features with Becker nevus, a mosaic disorder associated with post-zygotic ACTB mutations. Given the clinical and histopathological overlap between CSMH and …
BACKGROUND: Congenital smooth muscle hamartomas (CSMHs) are benign lesions that share clinical and histopathological features with Becker ne …
Further delineation of putative ACTB loss-of-function variants: A 4-patient series.
Baumann M, Beaver EM, Palomares-Bralo M, Santos-Simarro F, Holzer P, Povysil G, Müller T, Valovka T, Janecke AR. Baumann M, et al. Hum Mutat. 2020 Apr;41(4):753-758. doi: 10.1002/humu.23970. Epub 2020 Jan 16. Hum Mutat. 2020. PMID: 31898838 Free PMC article.
ACTB encodes beta-cytoplasmic actin, an essential component of the cytoskeleton. Based on chromosome 7p22.1 deletions that include the ACTB locus and on rare truncating ACTB variants, a phenotype resulting from ACTB haploinsufficiency was recently prop
ACTB encodes beta-cytoplasmic actin, an essential component of the cytoskeleton. Based on chromosome 7p22.1 deletions that include th
Mutant ACTB mRNA 3'-UTR promotes hepatocellular carcinoma development by regulating miR-1 and miR-29a.
Li Y, Ma H, Shi C, Feng F, Yang L. Li Y, et al. Cell Signal. 2020 Mar;67:109479. doi: 10.1016/j.cellsig.2019.109479. Epub 2019 Dec 14. Cell Signal. 2020. PMID: 31846694
In recent years, studies demonstrate that ACTB has been found to be associated with various tumors. Although ACTB is dysregulated in numerous cancer types, limited data are available on the potential function and mechanism of ACTB in hepatocellular carcinoma …
In recent years, studies demonstrate that ACTB has been found to be associated with various tumors. Although ACTB is dysregula …
1,702 results