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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1993 2
2003 1
2005 1
2009 2
2010 3
2011 1
2012 2
2013 1
2014 2
2015 3
2016 3
2017 2
2018 3
2019 7
2020 7
2021 6
2022 5
2023 6
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2025 15
2026 16

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81 results

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Page 1
Acetaminophen's Role in Autism and ADHD: A Mitochondrial Perspective.
Chu S, Woodfin S, Bayliss E, Smith M, Fulp A, Mirabelli E, Moore W. Chu S, et al. Int J Mol Sci. 2025 Sep 3;26(17):8585. doi: 10.3390/ijms26178585. Int J Mol Sci. 2025. PMID: 40943505 Free PMC article. Review.
One in 36 children were identified with autism in 2020, a 22% increase from 2018 and a 98% increase from 2010. Simultaneously, attention-deficit/hyperactivity disorder (ADHD) diagnoses increased 36% from 2003 to 2016-2019. ...However, numerous s …
One in 36 children were identified with autism in 2020, a 22% increase from 2018 and a 98% increase from 2010. Simultaneously, attention …
Mitochondrial dynamics dysfunction and neurodevelopmental disorders: From pathological mechanisms to clinical translation.
Yang Z, Luo Y, Yang Z, Liu Z, Li M, Wu X, Chen L, Xin W. Yang Z, et al. Neural Regen Res. 2026 May 1;21(5):1926-1946. doi: 10.4103/NRR.NRR-D-24-01422. Epub 2025 Jun 19. Neural Regen Res. 2026. PMID: 40537021 Free PMC article.
Mitochondrial dysfunction has emerged as a critical factor in the etiology of various neurodevelopmental disorders, including autism spectrum disorders, attention-deficit/hyperactivity disorder, and Rett syndrome. ...In autism spectrum di …
Mitochondrial dysfunction has emerged as a critical factor in the etiology of various neurodevelopmental disorders, including …
Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review.
Deepmala, Slattery J, Kumar N, Delhey L, Berk M, Dean O, Spielholz C, Frye R. Deepmala, et al. Neurosci Biobehav Rev. 2015 Aug;55:294-321. doi: 10.1016/j.neubiorev.2015.04.015. Epub 2015 May 6. Neurosci Biobehav Rev. 2015. PMID: 25957927 Free article.
Over the past decade, there has been growing evidence for the use of NAC in treating psychiatric and neurological disorders, considering its role in attenuating pathophysiological processes associated with these disorders, including oxidative stress, apoptosis, mitochondrial …
Over the past decade, there has been growing evidence for the use of NAC in treating psychiatric and neurological disorders, considering its …
DLG4-related synaptopathy: a new rare brain disorder.
Rodríguez-Palmero A, Boerrigter MM, Gómez-Andrés D, Aldinger KA, Marcos-Alcalde Í, Popp B, Everman DB, Lovgren AK, Arpin S, Bahrambeigi V, Beunders G, Bisgaard AM, Bjerregaard VA, Bruel AL, Challman TD, Cogné B, Coubes C, de Man SA, Denommé-Pichon AS, Dye TJ, Elmslie F, Feuk L, García-Miñaúr S, Gertler T, Giorgio E, Gruchy N, Haack TB, Haldeman-Englert CR, Haukanes BI, Hoyer J, Hurst ACE, Isidor B, Soller MJ, Kushary S, Kvarnung M, Landau YE, Leppig KA, Lindstrand A, Kleinendorst L, MacKenzie A, Mandrile G, Mendelsohn BA, Moghadasi S, Morton JE, Moutton S, Müller AJ, O'Leary M, Pacio-Míguez M, Palomares-Bralo M, Parikh S, Pfundt R, Pode-Shakked B, Rauch A, Repnikova E, Revah-Politi A, Ross MJ, Ruivenkamp CAL, Sarrazin E, Savatt JM, Schlüter A, Schönewolf-Greulich B, Shad Z, Shaw-Smith C, Shieh JT, Shohat M, Spranger S, Thiese H, Mau-Them FT, van Bon B, van de Burgt I, van de Laar IMBH, van Drie E, van Haelst MM, van Ravenswaaij-Arts CM, Verdura E, Vitobello A, Waldmüller S, Whiting S, Zweier C, Prada CE, de Vries BBA, Dobyns WB, Reiter SF, Gómez-Puertas P, Pujol A, Tümer Z. Rodríguez-Palmero A, et al. Genet Med. 2021 May;23(5):888-899. doi: 10.1038/s41436-020-01075-9. Epub 2021 Feb 17. Genet Med. 2021. PMID: 33597769 Free article.
RESULTS: The clinical picture was predominated by early onset global developmental delay, intellectual disability, autism spectrum disorder, and attention deficit-hyperactivity disorder, all of which point to a brain disorder. ...CONCLUSI …
RESULTS: The clinical picture was predominated by early onset global developmental delay, intellectual disability, autism spectrum disord …
Mitochondrial Dysfunction in Attention Deficit Hyperactivity Disorder.
Öğütlü H, Kaşak M, Tutku Tabur S. Öğütlü H, et al. Eurasian J Med. 2022 Dec;54(Suppl1):187-195. doi: 10.5152/eurasianjmed.2022.22187. Eurasian J Med. 2022. PMID: 36655466 Free PMC article.
Although studies considering the relationship between attention deficit hyperactivity disorder and mitochondrial dysfunction are less than those of autism spectrum disorder, schizophrenia, and mood disorders, studies on attentio …
Although studies considering the relationship between attention deficit hyperactivity disorder and mitochondr …
Spectrum of neuro-genetic disorders in the United Arab Emirates national population.
Saleh S, Beyyumi E, Al Kaabi A, Hertecant J, Barakat D, Al Dhaheri NS, Al-Gazali L, Al Shamsi A. Saleh S, et al. Clin Genet. 2021 Nov;100(5):573-600. doi: 10.1111/cge.14044. Epub 2021 Aug 19. Clin Genet. 2021. PMID: 34374989
Ninety-five (48% [95/197]) patients had autosomal recessive diseases, 40 mutations involved inborn errors of metabolism and 50 mutations involved genetic disorders. ...X-linked related disorders were found in 10 patients (5% [10/197]). Mitochondrial mutation was fou …
Ninety-five (48% [95/197]) patients had autosomal recessive diseases, 40 mutations involved inborn errors of metabolism and 50 mutati …
A systematic review on the role of mitochondrial dysfunction/disorders in neurodevelopmental disorders and psychiatric/behavioral disorders.
Pinto Payares DV, Spooner L, Vosters J, Dominguez S, Patrick L, Harris A, Kanungo S. Pinto Payares DV, et al. Front Psychiatry. 2024 Jun 28;15:1389093. doi: 10.3389/fpsyt.2024.1389093. eCollection 2024. Front Psychiatry. 2024. PMID: 39006821 Free PMC article.
The role of mitochondrial diseases/dysfunction has been highlighted in neurodevelopmental disorders like ASD, ADHD, intellectual disability, and speech delay, as well as various psychiatric conditions. ...We mostly found review articles with mention of …
The role of mitochondrial diseases/dysfunction has been highlighted in neurodevelopmental disorders like ASD, ADHD …
Methylphenidate triggers retinal oxidative stress and mitochondrial dysfunction under physiological conditions but has beneficial effects in inflammatory settings.
Sanches ES, Leitão RA, Baptista FI, Mota SI, Caldeira MV, Oliveira PJ, Ambrósio AF, Fernandes R, Silva AP. Sanches ES, et al. Neuropharmacology. 2025 Nov 15;279:110623. doi: 10.1016/j.neuropharm.2025.110623. Epub 2025 Aug 5. Neuropharmacology. 2025. PMID: 40752585 Free article.
Methylphenidate (MPH) is widely used as the first-line pharmacological treatment for attention-deficit/hyperactivity disorder (ADHD). However, its misuse as a cognitive enhancer has been increasing worldwide. ...Additionally, male Wistar Kyoto r …
Methylphenidate (MPH) is widely used as the first-line pharmacological treatment for attention-deficit/hyperactivity …
Creatine Deficiency Disorders.
Mercimek-Andrews S, Salomons GS. Mercimek-Andrews S, et al. 2009 Jan 15 [updated 2025 Aug 7]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. 2009 Jan 15 [updated 2025 Aug 7]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. PMID: 20301745 Free Books & Documents. Review.
Onset of clinical manifestations of GAMT deficiency (reported in ~130 individuals) is between ages three months and two years; in addition to developmental delays, the majority of individuals have epilepsy and develop a behavior disorder (e.g., hyperactivity, autism …
Onset of clinical manifestations of GAMT deficiency (reported in ~130 individuals) is between ages three months and two years; in addition t …
Attention deficit-hyperactivity disorder suffers from mitochondrial dysfunction.
Verma P, Singh A, Nthenge-Ngumbau DN, Rajamma U, Sinha S, Mukhopadhyay K, Mohanakumar KP. Verma P, et al. BBA Clin. 2016 Oct 18;6:153-158. doi: 10.1016/j.bbacli.2016.10.003. eCollection 2016 Dec. BBA Clin. 2016. PMID: 27896136 Free PMC article.
BACKGROUND: Pathophysiology of attention-deficit hyperactivity disorder (ADHD) is not known, and therefore the present study investigated mitochondrial defects, if any in cybrids created from patients and control population. ...CONCLUSION …
BACKGROUND: Pathophysiology of attention-deficit hyperactivity disorder (ADHD) is not known, and therefor …
81 results