AG-17047/AG/NIA NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2000	2
2001	1
2002	5
2003	3
2004	3
2005	1
2021	0

1

Aged-obese rats exhibit robust responses to a melanocortin agonist and antagonist despite leptin resistance.

Zhang Y, Matheny M, Tümer N, Scarpace PJ. Zhang Y, et al. Neurobiol Aging. 2004 Nov-Dec;25(10):1349-60. doi: 10.1016/j.neurobiolaging.2004.02.012. Neurobiol Aging. 2004. PMID: 15465633

2

Transcriptional regulation of uncoupling protein-2 gene expression in L6 myotubes.

Hatakeyama Y, Scarpace PJ. Hatakeyama Y, et al. Int J Obes Relat Metab Disord. 2001 Nov;25(11):1619-24. doi: 10.1038/sj.ijo.0801812. Int J Obes Relat Metab Disord. 2001. PMID: 11753581

3

Hypothalamic delivery of doxycycline-inducible leptin gene allows for reversible transgene expression and physiological responses.

Wilsey J, Zolotukhin S, Prima V, Shek EW, Matheny MK, Scarpace PJ. Wilsey J, et al. Gene Ther. 2002 Nov;9(22):1492-9. doi: 10.1038/sj.gt.3301835. Gene Ther. 2002. PMID: 12407421

4

Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II.

Scarpace PJ, Matheny M, Zolotukhin S, Tümer N, Zhang Y. Scarpace PJ, et al. Neuropharmacology. 2003 Aug;45(2):211-9. doi: 10.1016/s0028-3908(03)00158-8. Neuropharmacology. 2003. PMID: 12842127

5

Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats.

Scarpace PJ, Matheny M, Tümer N, Cheng KY, Zhang Y. Scarpace PJ, et al. Diabetologia. 2005 Jun;48(6):1075-83. doi: 10.1007/s00125-005-1763-x. Epub 2005 Apr 30. Diabetologia. 2005. PMID: 15864530

6

Peripheral but not central leptin prevents the immunosuppression associated with hypoleptinemia in rats.

Zhang Y, Wilsey JT, Frase CD, Matheny MM, Bender BS, Zolotukhin S, Scarpace PJ. Zhang Y, et al. J Endocrinol. 2002 Sep;174(3):455-61. doi: 10.1677/joe.0.1740455. J Endocrinol. 2002. PMID: 12208666

7

Central leptin gene therapy fails to overcome leptin resistance associated with diet-induced obesity.

Wilsey J, Zolotukhin S, Prima V, Scarpace PJ. Wilsey J, et al. Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R1011-20. doi: 10.1152/ajpregu.00193.2003. Am J Physiol Regul Integr Comp Physiol. 2003. PMID: 14557234 Free article.

8

Leptin-induced leptin resistance reveals separate roles for the anorexic and thermogenic responses in weight maintenance.

Scarpace PJ, Matheny M, Zhang Y, Shek EW, Prima V, Zolotukhin S, Tümer N. Scarpace PJ, et al. Endocrinology. 2002 Aug;143(8):3026-35. doi: 10.1210/endo.143.8.8966. Endocrinology. 2002. PMID: 12130569

9

Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats.

Li G, Mobbs CV, Scarpace PJ. Li G, et al. Diabetes. 2003 Aug;52(8):1951-7. doi: 10.2337/diabetes.52.8.1951. Diabetes. 2003. PMID: 12882910 Free article.

10

Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression.

Li G, Zhang Y, Wilsey JT, Scarpace PJ. Li G, et al. J Endocrinol. 2004 Jul;182(1):123-32. doi: 10.1677/joe.0.1820123. J Endocrinol. 2004. PMID: 15225137

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