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Page 1
Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening.
Pedró-Rosa L, Buckner FS, Ranade RM, Eberhart C, Madoux F, Gillespie JR, Koh CY, Brown S, Lohse J, Verlinde CL, Fan E, Bannister T, Scampavia L, Hol WG, Spicer T, Hodder P. Pedró-Rosa L, et al. J Biomol Screen. 2015 Jan;20(1):122-30. doi: 10.1177/1087057114548832. Epub 2014 Aug 27. J Biomol Screen. 2015. PMID: 25163684 Free PMC article.
Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia.
Larson ET, Kim JE, Napuli AJ, Verlinde CL, Fan E, Zucker FH, Van Voorhis WC, Buckner FS, Hol WG, Merritt EA. Larson ET, et al. Acta Crystallogr D Biol Crystallogr. 2012 Sep;68(Pt 9):1194-200. doi: 10.1107/S0907444912024699. Epub 2012 Aug 18. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22948920 Free PMC article.
Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity.
Johnson SM, Murphy RC, Geiger JA, DeRocher AE, Zhang Z, Ojo KK, Larson ET, Perera BG, Dale EJ, He P, Reid MC, Fox AM, Mueller NR, Merritt EA, Fan E, Parsons M, Van Voorhis WC, Maly DJ. Johnson SM, et al. J Med Chem. 2012 Mar 8;55(5):2416-26. doi: 10.1021/jm201713h. Epub 2012 Feb 27. J Med Chem. 2012. PMID: 22320388 Free PMC article.
34 results