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Year Number of Results
2004 2
2006 1
2007 2
2008 2
2010 2
2011 1
2020 0
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Page 1
Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulence.
Aziz RK, Kansal R, Aronow BJ, Taylor WL, Rowe SL, Kubal M, Chhatwal GS, Walker MJ, Kotb M. Aziz RK, et al. PLoS One. 2010 Apr 14;5(4):e9798. doi: 10.1371/journal.pone.0009798. PLoS One. 2010. PMID: 20418946 Free PMC article.
Unbiased forward genetics and systems biology approaches to understanding how gene-environment interactions work to predict susceptibility and outcomes of infections.
Kotb M, Fathey N, Aziz R, Rowe S, Williams RW, Lu L. Kotb M, et al. Novartis Found Symp. 2008;293:156-65; discussion 165-7, 181-3. doi: 10.1002/9780470696781.ch12. Novartis Found Symp. 2008. PMID: 18972751 Review.
Individual genetic variations directly effect polarization of cytokine responses to superantigens associated with streptococcal sepsis: implications for customized patient care.
Nooh MM, Nookala S, Kansal R, Kotb M. Nooh MM, et al. J Immunol. 2011 Mar 1;186(5):3156-63. doi: 10.4049/jimmunol.1002057. Epub 2011 Jan 31. J Immunol. 2011. PMID: 21282506 Free article.
Streptococcal mitogenic exotoxin, SmeZ, is the most susceptible M1T1 streptococcal superantigen to degradation by the streptococcal cysteine protease, SpeB.
Nooh MM, Aziz RK, Kotb M, Eroshkin A, Chuang WJ, Proft T, Kansal R. Nooh MM, et al. J Biol Chem. 2006 Nov 17;281(46):35281-8. doi: 10.1074/jbc.M605544200. Epub 2006 Sep 15. J Biol Chem. 2006. PMID: 16980693 Free article.
Dissection of the molecular basis for hypervirulence of an in vivo-selected phenotype of the widely disseminated M1T1 strain of group A Streptococcus bacteria.
Kansal RG, Datta V, Aziz RK, Abdeltawab NF, Rowe S, Kotb M. Kansal RG, et al. J Infect Dis. 2010 Mar 15;201(6):855-65. doi: 10.1086/651019. J Infect Dis. 2010. PMID: 20151844
Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB.
Aziz RK, Pabst MJ, Jeng A, Kansal R, Low DE, Nizet V, Kotb M. Aziz RK, et al. Mol Microbiol. 2004 Jan;51(1):123-34. doi: 10.1046/j.1365-2958.2003.03797.x. Mol Microbiol. 2004. PMID: 14651616 Free article.
Susceptibility to severe Streptococcal sepsis: use of a large set of isogenic mouse lines to study genetic and environmental factors.
Aziz RK, Kansal R, Abdeltawab NF, Rowe SL, Su Y, Carrigan D, Nooh MM, Attia RR, Brannen C, Gardner LA, Lu L, Williams RW, Kotb M. Aziz RK, et al. Genes Immun. 2007 Jul;8(5):404-15. doi: 10.1038/sj.gene.6364402. Epub 2007 May 24. Genes Immun. 2007. PMID: 17525705