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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2003 4
2004 2
2005 2
2006 5
2007 5
2008 5
2009 2
2010 7
2011 10
2012 6
2013 6
2014 5
2015 5
2016 6
2017 5
2018 5
2019 5
2020 5
2021 5
2023 0
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82 results
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Page 1
AM-1241 CB2 Receptor Agonist Attenuates Inflammation, Apoptosis and Stimulate Progenitor Cells in Bile Duct Ligated Rats.
Mahmoud HM, Osman M, Elshabrawy O, Abdallah HMI, Khairallah A. Mahmoud HM, et al. Open Access Maced J Med Sci. 2019 Mar 29;7(6):925-936. doi: 10.3889/oamjms.2019.194. eCollection 2019 Mar 30. Open Access Maced J Med Sci. 2019. PMID: 30976335 Free PMC article.
RESULTS: Following bile duct ligation (BDL) for 3 weeks, there was increased aminotransferase levels, marked inflammatory infiltration and hepatocyte apoptosis with induced oxidative stress, as reflected by increased lipid peroxidation. Conversely, following treatment with the CB …
RESULTS: Following bile duct ligation (BDL) for 3 weeks, there was increased aminotransferase levels, marked inflammatory infiltration and h …
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset.
Shoemaker JL, Seely KA, Reed RL, Crow JP, Prather PL. Shoemaker JL, et al. J Neurochem. 2007 Apr;101(1):87-98. doi: 10.1111/j.1471-4159.2006.04346.x. Epub 2007 Jan 4. J Neurochem. 2007. PMID: 17241118 Free PMC article.
More importantly, daily injections of the selective CB2 agonist AM-1241, initiated at symptom onset, increase the survival interval after disease onset by 56%. ...
More importantly, daily injections of the selective CB2 agonist AM-1241, initiated at symptom onset, increase the survival interval a …
Therapeutic modulation of cannabinoid lipid signaling: metabolic profiling of a novel antinociceptive cannabinoid-2 receptor agonist.
Wood JT, Smith DM, Janero DR, Zvonok AM, Makriyannis A. Wood JT, et al. Life Sci. 2013 Mar 19;92(8-9):482-91. doi: 10.1016/j.lfs.2012.06.019. Epub 2012 Jun 28. Life Sci. 2013. PMID: 22749867 Free PMC article.
Liquid chromatography and mass spectrometry techniques were used to quantify AM-1241 tissue distribution and metabolic conversion. KEY FINDINGS: AM-1241 bound extensively to plasma protein/albumin. A pharmacological AM-1241 dose (25mg/kg, i.v.) was administer …
Liquid chromatography and mass spectrometry techniques were used to quantify AM-1241 tissue distribution and metabolic conversion. KE …
[Study of antioxidant effect of cannabinoid receptor type 2 agonist on rat hepatic stellate cell line].
Shi Y, Wu YF, Long CZ, He P, Gu JY, Yang L, Wang YP. Shi Y, et al. Zhonghua Gan Zang Bing Za Zhi. 2018 Sep 20;26(9):660-665. doi: 10.3760/cma.j.issn.1007-3418.2018.09.005. Zhonghua Gan Zang Bing Za Zhi. 2018. PMID: 30481862 Chinese.
Objective: To investigate the action and antioxidant effects of CB2 agonist AM-1241 on rat hepatic stellate cell line (HSC-T6). Methods: HSC-T6 was randomly divided into four groups: control group, oxidative stress group, AM-1241 intervention group and AM-1241 …
Objective: To investigate the action and antioxidant effects of CB2 agonist AM-1241 on rat hepatic stellate cell line (HSC-T6). Metho …
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors.
Li X, Peng Z, Zhou Y, Wang J, Lin X, Dong X, Liu X, Jiang J, Jiang Y, Li L. Li X, et al. Toxicol Lett. 2019 Oct 1;313:77-90. doi: 10.1016/j.toxlet.2019.06.005. Epub 2019 Jun 18. Toxicol Lett. 2019. PMID: 31220554
Specific antagonists of CB1R (AM 281, Rimonabant), but not its agonist ACEA significantly ameliorated the heart histopathology induced by chronic quetiapine exposure. By contrast, specific agonists of CB2R (JWH-133, AM 1241), but not its antagonist AM 630 exerted beneficia …
Specific antagonists of CB1R (AM 281, Rimonabant), but not its agonist ACEA significantly ameliorated the heart histopathology induced by ch …
Diuretic effects of cannabinoids.
Paronis CA, Thakur GA, Bajaj S, Nikas SP, Vemuri VK, Makriyannis A, Bergman J. Paronis CA, et al. J Pharmacol Exp Ther. 2013 Jan;344(1):8-14. doi: 10.1124/jpet.112.199331. Epub 2012 Sep 27. J Pharmacol Exp Ther. 2013. PMID: 23019138 Free PMC article.
82 results