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Did you mean and cancer (5,374,836 results)?
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
Cao YF, Xie L, Tong BB, Chu MY, Shi WQ, Li X, He JZ, Wang SH, Wu ZY, Deng DX, Zheng YQ, Li ZM, Xu XE, Liao LD, Cheng YW, Li LY, Xu LY, Li EM. Cao YF, et al. Cell Death Differ. 2023 Feb;30(2):527-543. doi: 10.1038/s41418-022-01104-x. Epub 2022 Dec 16. Cell Death Differ. 2023. PMID: 36526897 Free PMC article.
Anillin (ANLN) is a mitosis-related protein that promotes contractile ring formation and cytokinesis, but its cell cycle-dependent degradation mechanisms in cancer cells remain unclear. ...Furthermore, the findings of the study showed that the deubiquitinating enzym …
Anillin (ANLN) is a mitosis-related protein that promotes contractile ring formation and cytokinesis, but its cell cycle-dependent de …
ANLN promotes carcinogenesis in oral cancer by regulating the PI3K/mTOR signaling pathway.
Wang B, Zhang XL, Li CX, Liu NN, Hu M, Gong ZC. Wang B, et al. Head Face Med. 2021 Jun 3;17(1):18. doi: 10.1186/s13005-021-00269-z. Head Face Med. 2021. PMID: 34082790 Free PMC article.
ANLN was reported to promote the progression of cancer. This study aims to investigate the role of ANLNin oral cancer and the underlying molecular mechanism. ...Patients with higher ANLN expression exhibitedshorter survivaltimes. ANLN was alsoab …
ANLN was reported to promote the progression of cancer. This study aims to investigate the role of ANLNin oral cancer a …
ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis.
Wang A, Dai H, Gong Y, Zhang C, Shu J, Luo Y, Jiang Y, Liu W, Bie P. Wang A, et al. J Exp Clin Cancer Res. 2019 Aug 8;38(1):347. doi: 10.1186/s13046-019-1340-7. J Exp Clin Cancer Res. 2019. PMID: 31395079 Free PMC article.
The ANLN protein expression in pancreatic cancer cell lines was detected by Western blot. ...These findings suggest that ANLN may be a candidate therapeutic target in pancreatic cancer....
The ANLN protein expression in pancreatic cancer cell lines was detected by Western blot. ...These findings suggest that AN …
Pan-cancer analysis of the prognostic and immunological role of ANLN: An onco-immunological biomarker.
Liu K, Cui L, Li C, Tang C, Niu Y, Hao J, Bu Y, Chen B. Liu K, et al. Front Genet. 2022 Aug 5;13:922472. doi: 10.3389/fgene.2022.922472. eCollection 2022. Front Genet. 2022. PMID: 35991576 Free PMC article.
ANLN facilitates tumor immune evasion through different mechanisms, which involve T-cell exclusion in different cancer types and tumor-infiltrating immune cells in colon adenocarcinoma, kidney renal clear cell carcinoma, liver hepatocellular carcinoma, and prostate …
ANLN facilitates tumor immune evasion through different mechanisms, which involve T-cell exclusion in different cancer types a …
Clinical implication and immunological landscape analyses of ANLN in pan-cancer: A new target for cancer research.
Zhang L, Wei Y, He Y, Wang X, Huang Z, Sun L, Chen J, Zhu Q, Zhou X. Zhang L, et al. Cancer Med. 2023 Feb;12(4):4907-4920. doi: 10.1002/cam4.5177. Epub 2022 Aug 28. Cancer Med. 2023. PMID: 36030492 Free PMC article.
However, the role of ANLN in pan-cancer prognosis and tumor immunity remains unclear. METHODS: Gene expression profiles of 31 solid tumors were downloaded from The Cancer Genome Atlas (TCGA) database. ...The BLCA immunotherapy cohort confirmed that patients w …
However, the role of ANLN in pan-cancer prognosis and tumor immunity remains unclear. METHODS: Gene expression profiles of 31 …
ANLN Enhances Triple-Negative Breast Cancer Stemness Through TWIST1 and BMP2 and Promotes its Spheroid Growth.
Maryam A, Chin YR. Maryam A, et al. Front Mol Biosci. 2021 Jul 1;8:700973. doi: 10.3389/fmolb.2021.700973. eCollection 2021. Front Mol Biosci. 2021. PMID: 34277708 Free PMC article.
ANLN is frequently upregulated in triple-negative breast cancer (TNBC) and its high expression in tumors are significantly associated with poor survival and recurrence, thereby it has been proposed to function as a prognostic marker for breast cancer. ...A …
ANLN is frequently upregulated in triple-negative breast cancer (TNBC) and its high expression in tumors are significantly ass …
Penfluridol suppresses MYC-driven ANLN expression and liver cancer progression by disrupting the KEAP1-NRF2 interaction.
Nguyen MT, Lee GJ, Kim B, Kim HJ, Tak J, Park MK, Kim EJ, Kang GJ, Rho SB, Lee H, Lee K, Kim SG, Lee CH. Nguyen MT, et al. Pharmacol Res. 2024 Dec;210:107512. doi: 10.1016/j.phrs.2024.107512. Epub 2024 Dec 4. Pharmacol Res. 2024. PMID: 39643070 Free article.
Currently, no treatment agents are known to suppress ANLN. Analysis of The Cancer Genome Atlas data showed that high ANLN expression is associated with poor prognosis and survival in HCC patients. ANLN knockdown was shown to inhibit proliferation, cell …
Currently, no treatment agents are known to suppress ANLN. Analysis of The Cancer Genome Atlas data showed that high ANLN …
Comprehensive Analysis of ANLN in Human Tumors: A Prognostic Biomarker Associated with Cancer Immunity.
Zhang X, Li L, Huang S, Liao W, Li J, Huang Z, Huang Y, Lian Y. Zhang X, et al. Oxid Med Cell Longev. 2022 Mar 17;2022:5322929. doi: 10.1155/2022/5322929. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35340220 Free PMC article.
Numerous studies have suggested that ANLN is upregulated in many cancer types, as well as significantly associated with patient prognosis and malignant cancer characteristics. ...KEGG analysis and the STRING tool were used to elucidate the potential mechanism …
Numerous studies have suggested that ANLN is upregulated in many cancer types, as well as significantly associated with patien …
MiR-16-5p suppresses breast cancer proliferation by targeting ANLN.
Wang Z, Hu S, Li X, Liu Z, Han D, Wang Y, Wei L, Zhang G, Wang X. Wang Z, et al. BMC Cancer. 2021 Nov 7;21(1):1188. doi: 10.1186/s12885-021-08914-1. BMC Cancer. 2021. PMID: 34743685 Free PMC article.
This study aimed to explore the role of miR-16-5p and ANLN in breast cancer (BC). METHODS: Cohort datasets of BC were obtained from the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas (TCGA) and analyzed by bioinformatics tools. qRT-PCR and western …
This study aimed to explore the role of miR-16-5p and ANLN in breast cancer (BC). METHODS: Cohort datasets of BC were obtained …
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.
Calvo F, Ege N, Grande-Garcia A, Hooper S, Jenkins RP, Chaudhry SI, Harrington K, Williamson P, Moeendarbary E, Charras G, Sahai E. Calvo F, et al. Nat Cell Biol. 2013 Jun;15(6):637-46. doi: 10.1038/ncb2756. Epub 2013 May 26. Nat Cell Biol. 2013. PMID: 23708000 Free PMC article.
To learn more about cancer-associated fibroblasts (CAFs), we have isolated fibroblasts from different stages of breast cancer progression and analysed their function and gene expression. ...YAP function is required for CAFs to promote matrix stiffening, cancer …
To learn more about cancer-associated fibroblasts (CAFs), we have isolated fibroblasts from different stages of breast cancer …
225 results