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Year Number of Results
1998 1
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17 results

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Page 1
Intracellular and extracellular activities of V-domain Ig-containing suppressor of T cell activation (VISTA) modulated by immunosuppressive factors of tumour microenvironment.
Abooali M, Schlichtner S, Lei X, Aliu N, Ruggiero S, Loges S, Ziegler M, Hertel F, Volckmar AL, Stenzinger A, Christopoulos P, Thomas M, Klenova E, Meyer NH, Boussios S, Heaton N, Zen Y, Zamalloa A, Chokshi S, Urbani L, Richard S, Kirubendran K, Hussain R, Siligardi G, Cholewa D, Berger SM, Yasinska IM, Fasler-Kan E, Sumbayev VV. Abooali M, et al. Cancer Lett. 2025 Apr 28;616:217581. doi: 10.1016/j.canlet.2025.217581. Epub 2025 Feb 20. Cancer Lett. 2025. PMID: 39983894 Free article.
We found that VISTA expression can be differentially controlled by crucial factors present in TME, such as transforming growth factor beta type 1 (TGF-beta) and hypoxia as well as other factors activating hypoxic signalling. ...These networks include: …
We found that VISTA expression can be differentially controlled by crucial factors present in TME, such as transforming growth fac …
Stress-activated kinases regulate protein stability.
Fuchs SY, Fried VA, Ronai Z. Fuchs SY, et al. Oncogene. 1998 Sep 17;17(11 Reviews):1483-90. doi: 10.1038/sj.onc.1202184. Oncogene. 1998. PMID: 9779995 Review.
These interacting systems are seen in the response of p53, c-jun and ATF-2 in cells subjected to stress or DNA damage and to the normal regulated response in a variety of pathways including the IkappaB-NFkappaB and JAK-STAT pathways. The interweaving o …
These interacting systems are seen in the response of p53, c-jun and ATF-2 in cells subjected to stress or DNA damage and to t …
Marek's disease herpesvirus transforming protein MEQ: a c-Jun analogue with an alternative life style.
Liu JL, Kung HJ. Liu JL, et al. Virus Genes. 2000;21(1-2):51-64. Virus Genes. 2000. PMID: 11022789 Review.
These proteins exploit the existing host machinery and allow viruses to readily integrate into the host functional network. As a result, viruses are able to maneuver their journey seemingly effortlessly inside the host cell to achieve ultimate survival. ...MEQ is a basic r …
These proteins exploit the existing host machinery and allow viruses to readily integrate into the host functional network. As a resu …
Involvement of the CREB5 regulatory network in colorectal cancer metastasis.
Qi L, Ding Y. Qi L, et al. Yi Chuan. 2014 Jul;36(7):679-84. doi: 10.3724/SP.J.1005.2014.0679. Yi Chuan. 2014. PMID: 25076032
The signal regulatory network involved in colorectal cancer metastasis is complicated and thus the search for key control steps in the network is of great significance for unraveling colorectal cancer metastasis mechanism and finding drug-target site. ...Based on th …
The signal regulatory network involved in colorectal cancer metastasis is complicated and thus the search for key control steps in th …
Noise decomposition of intracellular biochemical signaling networks using nonequivalent reporters.
Rhee A, Cheong R, Levchenko A. Rhee A, et al. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17330-5. doi: 10.1073/pnas.1411932111. Epub 2014 Nov 17. Proc Natl Acad Sci U S A. 2014. PMID: 25404303 Free PMC article.
Using the noise mapping analysis, we find that the c-Jun N-terminal kinase (JNK) pathway generates higher noise than the NF-kappaB pathway, whereas the activation of c-Jun adds a greater amount of noise than the activation of ATF-2. In addition, we fin …
Using the noise mapping analysis, we find that the c-Jun N-terminal kinase (JNK) pathway generates higher noise than the NF-kappaB …
A review of adaptive mechanisms in cell responses towards oxidative stress caused by dental resin monomers.
Krifka S, Spagnuolo G, Schmalz G, Schweikl H. Krifka S, et al. Biomaterials. 2013 Jun;34(19):4555-63. doi: 10.1016/j.biomaterials.2013.03.019. Epub 2013 Mar 27. Biomaterials. 2013. PMID: 23541107 Review.
We will also consider the influence of monomer-induced oxidative stress on central signal transduction pathways including mitogen-activated protein kinases (MAPK) ERK1/2, p38, and JNK as well as the stress-activated transcription factors downstream Elk-1, …
We will also consider the influence of monomer-induced oxidative stress on central signal transduction pathways including mitogen-act …
Analysis and Validation of Differentially Expressed Ferroptosis-Related Genes in Regorafenib-Induced Cardiotoxicity.
Zhang S, Xu X, Li Z, Yi T, Ma J, Zhang Y, Li Y. Zhang S, et al. Oxid Med Cell Longev. 2022 Sep 26;2022:2513263. doi: 10.1155/2022/2513263. eCollection 2022. Oxid Med Cell Longev. 2022. Retraction in: Oxid Med Cell Longev. 2023 Dec 29;2023:9862498. doi: 10.1155/2023/9862498. PMID: 36204517 Free PMC article. Retracted.
Then, Gene Ontology (GO) Enrichment Analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) Enrichment Analysis, and Gene Set Enrichment Analysis (GSEA) were used to explore DEGs' bioinformatics functions and enriched pathways. We intersected DEGs with 259 ferroptosis-rel …
Then, Gene Ontology (GO) Enrichment Analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) Enrichment Analysis, and Gene Set Enrichment An …
Screening and regulatory network analysis of survival-related genes of patients with colorectal cancer.
Qi L, Ding Y. Qi L, et al. Sci China Life Sci. 2014 May;57(5):526-31. doi: 10.1007/s11427-014-4650-1. Epub 2014 Apr 11. Sci China Life Sci. 2014. PMID: 24722856
Therefore, the following screening and analysis were conducted on these 235 genes in this study. First, the enrichment analysis of transcription factor binding sites was conducted on the 235 genes. Genes with more than seven transcription factor bindin …
Therefore, the following screening and analysis were conducted on these 235 genes in this study. First, the enrichment analysis of transc …
Enrichment of genomic pathways based on differential DNA methylation profiles associated with chronic musculoskeletal pain in older adults: An exploratory study.
Montesino-Goicolea S, Sinha P, Huo Z, Rani A, Foster TC, Cruz-Almeida Y. Montesino-Goicolea S, et al. Mol Pain. 2020 Jan-Dec;16:1744806920966902. doi: 10.1177/1744806920966902. Mol Pain. 2020. PMID: 33073674 Free PMC article.
All CpG probes were clustered into 5966 regions, among which 600 regions were differentially methylated at p 0.05 level, including 294 hypermethylated regions and 306 hypomethylated regions (differentially methylated regions). Ingenuity pathway enrichment analysis revealed …
All CpG probes were clustered into 5966 regions, among which 600 regions were differentially methylated at p 0.05 level, including 294 hyper …
Activation of stress-regulated transcription factors by triethylene glycol dimethacrylate monomer.
Krifka S, Petzel C, Bolay C, Hiller KA, Spagnuolo G, Schmalz G, Schweikl H. Krifka S, et al. Biomaterials. 2011 Mar;32(7):1787-95. doi: 10.1016/j.biomaterials.2010.11.031. Epub 2010 Dec 10. Biomaterials. 2011. PMID: 21145583
These changes in the expression and activation of stress-related transcription factors were time-related to the induction of apoptosis by TEGDMA in all cell lines. The present study provides experimental evidence that TEGDMA interferes with the regulation of cellula …
These changes in the expression and activation of stress-related transcription factors were time-related to the induction of a …
17 results