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ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal dopamine-beta-hydroxylase.
Schmidt K, Ralle M, Schaffer T, Jayakanthan S, Bari B, Muchenditsi A, Lutsenko S. Schmidt K, et al. J Biol Chem. 2018 Dec 28;293(52):20085-20098. doi: 10.1074/jbc.RA118.004889. Epub 2018 Oct 19. J Biol Chem. 2018. PMID: 30341172 Free PMC article.
The copper (Cu) transporters ATPase copper-transporting alpha (ATP7A) and ATPase copper-transporting beta (ATP7B) are essential for the normal function of the mammalian central nervous system. ...These results establish d
The copper (Cu) transporters ATPase copper-transporting alpha (ATP7A) and ATPase copper-transporting b
The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum.
Barnes N, Tsivkovskii R, Tsivkovskaia N, Lutsenko S. Barnes N, et al. J Biol Chem. 2005 Mar 11;280(10):9640-5. doi: 10.1074/jbc.M413840200. Epub 2005 Jan 5. J Biol Chem. 2005. PMID: 15634671 Free article.
Copper is essential for brain metabolism, serving as a cofactor to superoxide dismutase, dopamine-beta-hydroxylase, amyloid precursor protein, ceruloplasmin, and other proteins required for normal brain function. ...The induced cell-speci
Copper is essential for brain metabolism, serving as a cofactor to superoxide dismutase, dopamine-beta-hydroxylase