Abbott Derek W - Search Results

Year	Number of Results
2003	1
2004	2
2005	2
2007	2
2008	1
2009	3
2010	4
2011	2
2012	4
2013	5
2014	3
2015	1
2016	4
2017	4
2018	9
2019	3
2020	3
2021	2
2022	4
2023	3
2024	2
2025	1

1

Restraint of inflammasome-driven cytokine responses through the mRNA stability protein TTP.

O'Keefe ME, Kondolf HC, De Santis S, Pizarro TT, Abbott DW. O'Keefe ME, et al. Among authors: abbott dw. Cell Rep. 2025 Feb 20;44(3):115340. doi: 10.1016/j.celrep.2025.115340. Online ahead of print. Cell Rep. 2025. PMID: 39982821 Free article.

2

Post-translational control of NLRP3 inflammasome signaling.

O'Keefe ME, Dubyak GR, Abbott DW. O'Keefe ME, et al. Among authors: abbott dw. J Biol Chem. 2024 Jun;300(6):107386. doi: 10.1016/j.jbc.2024.107386. Epub 2024 May 17. J Biol Chem. 2024. PMID: 38763335 Free PMC article. Review.

3

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.

Rana N, Privitera G, Kondolf HC, Bulek K, Lechuga S, De Salvo C, Corridoni D, Antanaviciute A, Maywald RL, Hurtado AM, Zhao J, Huang EH, Li X, Chan ER, Simmons A, Bamias G, Abbott DW, Heaney JD, Ivanov AI, Pizarro TT. Rana N, et al. Among authors: abbott dw. Cell. 2024 Feb 15;187(4):1011-1015. doi: 10.1016/j.cell.2024.01.010. Cell. 2024. PMID: 38364781 Free article. No abstract available.

4

Chemical modulation of gasdermin D activity: Therapeutic implications and consequences.

Zhou B, Abbott DW. Zhou B, et al. Among authors: abbott dw. Semin Immunol. 2023 Nov;70:101845. doi: 10.1016/j.smim.2023.101845. Epub 2023 Oct 8. Semin Immunol. 2023. PMID: 37806032 Free PMC article. Review.

5

Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.

Lethier M, Huard K, Hons M, Favier A, Brutscher B, Boeri Erba E, Abbott DW, Cusack S, Pellegrini E. Lethier M, et al. Among authors: abbott dw. Life Sci Alliance. 2023 Sep 6;6(11):e202201784. doi: 10.26508/lsa.202201784. Print 2023 Nov. Life Sci Alliance. 2023. PMID: 37673444 Free PMC article.

6

Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis.

Kondolf HC, D'Orlando DA, Dubyak GR, Abbott DW. Kondolf HC, et al. Among authors: abbott dw. J Biol Chem. 2023 Feb;299(2):102908. doi: 10.1016/j.jbc.2023.102908. Epub 2023 Jan 13. J Biol Chem. 2023. PMID: 36642180 Free PMC article.

7

Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies.

Zhou B, Ryder CB, Dubyak GR, Abbott DW. Zhou B, et al. Among authors: abbott dw. Sci Signal. 2022 Dec 20;15(765):eabl6781. doi: 10.1126/scisignal.abl6781. Epub 2022 Dec 20. Sci Signal. 2022. PMID: 36538593 Free PMC article.

8

TH17 cells promote CNS inflammation by sensing danger signals via Mincle.

Zhang Q, Liu W, Wang H, Zhou H, Bulek K, Chen X, Zhang CJ, Zhao J, Zhang R, Liu C, Kang Z, Bermel RA, Dubyak G, Abbott DW, Xiao TS, Nagy LE, Li X. Zhang Q, et al. Among authors: abbott dw. Nat Commun. 2022 May 3;13(1):2406. doi: 10.1038/s41467-022-30174-1. Nat Commun. 2022. PMID: 35504893 Free PMC article.

9

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis.

Rana N, Privitera G, Kondolf HC, Bulek K, Lechuga S, De Salvo C, Corridoni D, Antanaviciute A, Maywald RL, Hurtado AM, Zhao J, Huang EH, Li X, Chan ER, Simmons A, Bamias G, Abbott DW, Heaney JD, Ivanov AI, Pizarro TT. Rana N, et al. Among authors: abbott dw. Cell. 2022 Jan 20;185(2):283-298.e17. doi: 10.1016/j.cell.2021.12.024. Epub 2022 Jan 11. Cell. 2022. PMID: 35021065 Free PMC article.

10

Chemical Modulation of Gasdermin-Mediated Pyroptosis and Therapeutic Potential.

Ryder CB, Kondolf HC, O'Keefe ME, Zhou B, Abbott DW. Ryder CB, et al. Among authors: abbott dw. J Mol Biol. 2022 Feb 28;434(4):167183. doi: 10.1016/j.jmb.2021.167183. Epub 2021 Aug 3. J Mol Biol. 2022. PMID: 34358546 Free PMC article. Review.

11

Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases.

Zhou B, Abbott DW. Zhou B, et al. Among authors: abbott dw. Cell Rep. 2021 Apr 13;35(2):108998. doi: 10.1016/j.celrep.2021.108998. Cell Rep. 2021. PMID: 33852854 Free PMC article.

12

Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.

Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott DW, Xiao TS. Liu Z, et al. Among authors: abbott dw. Immunity. 2020 Jul 14;53(1):106-114.e5. doi: 10.1016/j.immuni.2020.06.007. Epub 2020 Jun 17. Immunity. 2020. PMID: 32553275 Free PMC article.

13

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis.

Karmakar M, Minns M, Greenberg EN, Diaz-Aponte J, Pestonjamasp K, Johnson JL, Rathkey JK, Abbott DW, Wang K, Shao F, Catz SD, Dubyak GR, Pearlman E. Karmakar M, et al. Among authors: abbott dw. Nat Commun. 2020 May 5;11(1):2212. doi: 10.1038/s41467-020-16043-9. Nat Commun. 2020. PMID: 32371889 Free PMC article.

14

Human polymorphisms in GSDMD alter the inflammatory response.

Rathkey JK, Xiao TS, Abbott DW. Rathkey JK, et al. Among authors: abbott dw. J Biol Chem. 2020 Mar 6;295(10):3228-3238. doi: 10.1074/jbc.RA119.010604. Epub 2020 Jan 27. J Biol Chem. 2020. PMID: 31988247 Free PMC article.

15

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.

Zammit NW, Siggs OM, Gray PE, Horikawa K, Langley DB, Walters SN, Daley SR, Loetsch C, Warren J, Yap JY, Cultrone D, Russell A, Malle EK, Villanueva JE, Cowley MJ, Gayevskiy V, Dinger ME, Brink R, Zahra D, Chaudhri G, Karupiah G, Whittle B, Roots C, Bertram E, Yamada M, Jeelall Y, Enders A, Clifton BE, Mabbitt PD, Jackson CJ, Watson SR, Jenne CN, Lanier LL, Wiltshire T, Spitzer MH, Nolan GP, Schmitz F, Aderem A, Porebski BT, Buckle AM, Abbott DW, Ziegler JB, Craig ME, Benitez-Aguirre P, Teo J, Tangye SG, King C, Wong M, Cox MP, Phung W, Tang J, Sandoval W, Wertz IE, Christ D, Goodnow CC, Grey ST. Zammit NW, et al. Among authors: abbott dw. Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18. Nat Immunol. 2019. PMID: 31534238

16

Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.

Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS. Liu Z, et al. Among authors: abbott dw. Immunity. 2019 Jul 16;51(1):43-49.e4. doi: 10.1016/j.immuni.2019.04.017. Epub 2019 May 13. Immunity. 2019. PMID: 31097341 Free PMC article.

17

TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.

Zhang CJ, Jiang M, Zhou H, Liu W, Wang C, Kang Z, Han B, Zhang Q, Chen X, Xiao J, Fisher A, Kaiser WJ, Murayama MA, Iwakura Y, Gao J, Carman J, Dongre A, Dubyak G, Abbott DW, Shi FD, Ransohoff RM, Li X. Zhang CJ, et al. Among authors: abbott dw. J Clin Invest. 2018 Dec 3;128(12):5399-5412. doi: 10.1172/JCI121901. Epub 2018 Oct 29. J Clin Invest. 2018. PMID: 30372424 Free PMC article.

18

Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models.

Liu X, Taftaf R, Kawaguchi M, Chang YF, Chen W, Entenberg D, Zhang Y, Gerratana L, Huang S, Patel DB, Tsui E, Adorno-Cruz V, Chirieleison SM, Cao Y, Harney AS, Patel S, Patsialou A, Shen Y, Avril S, Gilmore HL, Lathia JD, Abbott DW, Cristofanilli M, Condeelis JS, Liu H. Liu X, et al. Among authors: abbott dw. Cancer Discov. 2019 Jan;9(1):96-113. doi: 10.1158/2159-8290.CD-18-0065. Epub 2018 Oct 25. Cancer Discov. 2019. PMID: 30361447 Free PMC article.

19

IL-33 promotes recovery from acute colitis by inducing miR-320 to stimulate epithelial restitution and repair.

Lopetuso LR, De Salvo C, Pastorelli L, Rana N, Senkfor HN, Petito V, Di Martino L, Scaldaferri F, Gasbarrini A, Cominelli F, Abbott DW, Goodman WA, Pizarro TT. Lopetuso LR, et al. Among authors: abbott dw. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9362-E9370. doi: 10.1073/pnas.1803613115. Epub 2018 Sep 17. Proc Natl Acad Sci U S A. 2018. PMID: 30224451 Free PMC article.

20

Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis.

Rathkey JK, Zhao J, Liu Z, Chen Y, Yang J, Kondolf HC, Benson BL, Chirieleison SM, Huang AY, Dubyak GR, Xiao TS, Li X, Abbott DW. Rathkey JK, et al. Among authors: abbott dw. Sci Immunol. 2018 Aug 24;3(26):eaat2738. doi: 10.1126/sciimmunol.aat2738. Sci Immunol. 2018. PMID: 30143556 Free PMC article.

21

Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.

Chirieleison SM, Rathkey JK, Abbott DW. Chirieleison SM, et al. Among authors: abbott dw. Sci Signal. 2018 Jul 17;11(539):eaao3964. doi: 10.1126/scisignal.aao3964. Sci Signal. 2018. PMID: 30018081 Free PMC article.

22

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.

Yang J, Liu Z, Wang C, Yang R, Rathkey JK, Pinkard OW, Shi W, Chen Y, Dubyak GR, Abbott DW, Xiao TS. Yang J, et al. Among authors: abbott dw. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6792-6797. doi: 10.1073/pnas.1800562115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891674 Free PMC article.

23

Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.

Liu Z, Wang C, Rathkey JK, Yang J, Dubyak GR, Abbott DW, Xiao TS. Liu Z, et al. Among authors: abbott dw. Structure. 2018 May 1;26(5):778-784.e3. doi: 10.1016/j.str.2018.03.002. Epub 2018 Mar 22. Structure. 2018. PMID: 29576317 Free PMC article.

24

Phosphorylation of the E3 ubiquitin protein ligase ITCH diminishes binding to its cognate E2 ubiquitin ligase.

Perez JM, Chen Y, Xiao TS, Abbott DW. Perez JM, et al. Among authors: abbott dw. J Biol Chem. 2018 Jan 19;293(3):1100-1105. doi: 10.1074/jbc.RA117.000408. Epub 2017 Dec 6. J Biol Chem. 2018. PMID: 29212706 Free PMC article.

25

ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC.

Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J. Dziedzic SA, et al. Among authors: abbott dw. Nat Cell Biol. 2018 Jan;20(1):58-68. doi: 10.1038/s41556-017-0003-1. Epub 2017 Dec 4. Nat Cell Biol. 2018. PMID: 29203883 Free PMC article.

26

Live-cell visualization of gasdermin D-driven pyroptotic cell death.

Rathkey JK, Benson BL, Chirieleison SM, Yang J, Xiao TS, Dubyak GR, Huang AY, Abbott DW. Rathkey JK, et al. Among authors: abbott dw. J Biol Chem. 2017 Sep 1;292(35):14649-14658. doi: 10.1074/jbc.M117.797217. Epub 2017 Jul 18. J Biol Chem. 2017. PMID: 28726636 Free PMC article.

27

Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.

Chirieleison SM, Marsh RA, Kumar P, Rathkey JK, Dubyak GR, Abbott DW. Chirieleison SM, et al. Among authors: abbott dw. J Biol Chem. 2017 Jun 9;292(23):9666-9679. doi: 10.1074/jbc.M117.781500. Epub 2017 Apr 12. J Biol Chem. 2017. PMID: 28404814 Free PMC article.

28

Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity.

Dorand RD, Nthale J, Myers JT, Barkauskas DS, Avril S, Chirieleison SM, Pareek TK, Abbott DW, Stearns DS, Letterio JJ, Huang AY, Petrosiute A. Dorand RD, et al. Among authors: abbott dw. Science. 2016 Jul 22;353(6297):399-403. doi: 10.1126/science.aae0477. Epub 2016 Jul 21. Science. 2016. PMID: 27463676 Free PMC article.

29

Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides.

Russo HM, Rathkey J, Boyd-Tressler A, Katsnelson MA, Abbott DW, Dubyak GR. Russo HM, et al. Among authors: abbott dw. J Immunol. 2016 Aug 15;197(4):1353-67. doi: 10.4049/jimmunol.1600699. Epub 2016 Jul 6. J Immunol. 2016. PMID: 27385778 Free PMC article.

30

Synthetic Biology Reveals the Uniqueness of the RIP Kinase Domain.

Chirieleison SM, Kertesy SB, Abbott DW. Chirieleison SM, et al. Among authors: abbott dw. J Immunol. 2016 May 15;196(10):4291-7. doi: 10.4049/jimmunol.1502631. Epub 2016 Apr 4. J Immunol. 2016. PMID: 27045108 Free PMC article.

31

IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis.

De Salvo C, Wang XM, Pastorelli L, Mattioli B, Omenetti S, Buela KA, Chowdhry S, Garg RR, Goodman WA, Rodriguez-Palacios A, Smith DE, Abbott DW, Cominelli F, Bamias G, Xin W, Lee JJ, Vecchi M, Pizarro TT. De Salvo C, et al. Among authors: abbott dw. Am J Pathol. 2016 Apr;186(4):885-98. doi: 10.1016/j.ajpath.2015.11.028. Epub 2016 Feb 22. Am J Pathol. 2016. PMID: 26908008 Free PMC article.

32

An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation.

Perez JM, Chirieleison SM, Abbott DW. Perez JM, et al. Among authors: abbott dw. Cell Rep. 2015 Jul 28;12(4):537-44. doi: 10.1016/j.celrep.2015.06.050. Epub 2015 Jul 16. Cell Rep. 2015. PMID: 26190110 Free PMC article.

33

In vivo inhibition of RIPK2 kinase alleviates inflammatory disease.

Tigno-Aranjuez JT, Benderitter P, Rombouts F, Deroose F, Bai X, Mattioli B, Cominelli F, Pizarro TT, Hoflack J, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. J Biol Chem. 2014 Oct 24;289(43):29651-64. doi: 10.1074/jbc.M114.591388. Epub 2014 Sep 11. J Biol Chem. 2014. PMID: 25213858 Free PMC article.

34

Myeloid glycosylation defects lead to a spontaneous common variable immunodeficiency-like condition with associated hemolytic anemia and antilymphocyte autoimmunity.

Ryan SO, Abbott DW, Cobb BA. Ryan SO, et al. Among authors: abbott dw. J Immunol. 2014 Jun 15;192(12):5561-70. doi: 10.4049/jimmunol.1400385. Epub 2014 May 2. J Immunol. 2014. PMID: 24795453 Free PMC article.

35

Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses.

Ryan SO, Leal SM Jr, Abbott DW, Pearlman E, Cobb BA. Ryan SO, et al. Among authors: abbott dw. Glycobiology. 2014 Mar;24(3):262-71. doi: 10.1093/glycob/cwt107. Epub 2013 Dec 4. Glycobiology. 2014. PMID: 24310166 Free PMC article.

36

Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.

Corridoni D, Kodani T, Rodriguez-Palacios A, Pizarro TT, Xin W, Nickerson KP, McDonald C, Ley KF, Abbott DW, Cominelli F. Corridoni D, et al. Among authors: abbott dw. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16999-7004. doi: 10.1073/pnas.1311657110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082103 Free PMC article.

37

Innate immune-directed NF-κB signaling requires site-specific NEMO ubiquitination.

Jun JC, Kertesy S, Jones MB, Marinis JM, Cobb BA, Tigno-Aranjuez JT, Abbott DW. Jun JC, et al. Among authors: abbott dw. Cell Rep. 2013 Jul 25;4(2):352-61. doi: 10.1016/j.celrep.2013.06.036. Epub 2013 Jul 18. Cell Rep. 2013. PMID: 23871670 Free PMC article.

38

RIP2 activity in inflammatory disease and implications for novel therapeutics.

Jun JC, Cominelli F, Abbott DW. Jun JC, et al. Among authors: abbott dw. J Leukoc Biol. 2013 Nov;94(5):927-32. doi: 10.1189/jlb.0213109. Epub 2013 Jun 21. J Leukoc Biol. 2013. PMID: 23794710 Free PMC article. Review.

39

A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.

Tigno-Aranjuez JT, Bai X, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. Mol Cell Biol. 2013 Jan;33(1):146-58. doi: 10.1128/MCB.01049-12. Epub 2012 Oct 29. Mol Cell Biol. 2013. PMID: 23109427 Free PMC article.

40

IκB kinase α phosphorylation of TRAF4 downregulates innate immune signaling.

Marinis JM, Hutti JE, Homer CR, Cobb BA, Cantley LC, McDonald C, Abbott DW. Marinis JM, et al. Among authors: abbott dw. Mol Cell Biol. 2012 Jul;32(13):2479-89. doi: 10.1128/MCB.00106-12. Epub 2012 Apr 30. Mol Cell Biol. 2012. PMID: 22547678 Free PMC article.

41

Ubiquitination and phosphorylation in the regulation of NOD2 signaling and NOD2-mediated disease.

Tigno-Aranjuez JT, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. Biochim Biophys Acta. 2012 Nov;1823(11):2022-8. doi: 10.1016/j.bbamcr.2012.03.017. Epub 2012 Apr 11. Biochim Biophys Acta. 2012. PMID: 22522061 Free PMC article. Review.

42

TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.

Liu YC, Simmons DP, Li X, Abbott DW, Boom WH, Harding CV. Liu YC, et al. Among authors: abbott dw. J Immunol. 2012 Feb 1;188(3):1019-26. doi: 10.4049/jimmunol.1102181. Epub 2012 Jan 6. J Immunol. 2012. PMID: 22227568 Free PMC article.

43

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1.

Shembade N, Pujari R, Harhaj NS, Abbott DW, Harhaj EW. Shembade N, et al. Among authors: abbott dw. Nat Immunol. 2011 Jul 17;12(9):834-43. doi: 10.1038/ni.2066. Nat Immunol. 2011. PMID: 21765415 Free PMC article.

44

Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.

Tigno-Aranjuez JT, Asara JM, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. Genes Dev. 2010 Dec 1;24(23):2666-77. doi: 10.1101/gad.1964410. Genes Dev. 2010. PMID: 21123652 Free PMC article.

45

A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responses.

Marinis JM, Homer CR, McDonald C, Abbott DW. Marinis JM, et al. Among authors: abbott dw. J Biol Chem. 2011 Jan 21;286(3):1938-50. doi: 10.1074/jbc.M110.189308. Epub 2010 Nov 19. J Biol Chem. 2011. PMID: 21097508 Free PMC article.

46

Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice.

Gorfu G, Rivera-Nieves J, Hoang S, Abbott DW, Arbenz-Smith K, Azar DW, Pizarro TT, Cominelli F, McDuffie M, Ley K. Gorfu G, et al. Among authors: abbott dw. J Immunol. 2010 Nov 1;185(9):5561-8. doi: 10.4049/jimmunol.0903938. Epub 2010 Oct 6. J Immunol. 2010. PMID: 20926792 Free PMC article.

47

CpG-B oligodeoxynucleotides inhibit TLR-dependent and -independent induction of type I IFN in dendritic cells.

Liu YC, Gray RC, Hardy GA, Kuchtey J, Abbott DW, Emancipator SN, Harding CV. Liu YC, et al. Among authors: abbott dw. J Immunol. 2010 Apr 1;184(7):3367-76. doi: 10.4049/jimmunol.0903079. Epub 2010 Feb 24. J Immunol. 2010. PMID: 20181884 Free PMC article.

48

Binding of pro-prion to filamin A disrupts cytoskeleton and correlates with poor prognosis in pancreatic cancer.

Li C, Yu S, Nakamura F, Yin S, Xu J, Petrolla AA, Singh N, Tartakoff A, Abbott DW, Xin W, Sy MS. Li C, et al. Among authors: abbott dw. J Clin Invest. 2009 Sep;119(9):2725-36. doi: 10.1172/JCI39542. Epub 2009 Aug 17. J Clin Invest. 2009. PMID: 19690385 Free PMC article.

49

ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.

Tao M, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, Abbott DW. Tao M, et al. Among authors: abbott dw. Curr Biol. 2009 Aug 11;19(15):1255-63. doi: 10.1016/j.cub.2009.06.038. Epub 2009 Jul 9. Curr Biol. 2009. PMID: 19592251 Free PMC article.

50

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation.

Hutti JE, Shen RR, Abbott DW, Zhou AY, Sprott KM, Asara JM, Hahn WC, Cantley LC. Hutti JE, et al. Among authors: abbott dw. Mol Cell. 2009 May 14;34(4):461-72. doi: 10.1016/j.molcel.2009.04.031. Mol Cell. 2009. PMID: 19481526 Free PMC article.

51

MEKK4 sequesters RIP2 to dictate NOD2 signal specificity.

Clark NM, Marinis JM, Cobb BA, Abbott DW. Clark NM, et al. Among authors: abbott dw. Curr Biol. 2008 Sep 23;18(18):1402-8. doi: 10.1016/j.cub.2008.07.084. Epub 2008 Sep 4. Curr Biol. 2008. PMID: 18775659 Free PMC article.

52

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway.

Hutti JE, Turk BE, Asara JM, Ma A, Cantley LC, Abbott DW. Hutti JE, et al. Among authors: abbott dw. Mol Cell Biol. 2007 Nov;27(21):7451-61. doi: 10.1128/MCB.01101-07. Epub 2007 Aug 20. Mol Cell Biol. 2007. PMID: 17709380 Free PMC article.

53

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.

Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC. Abbott DW, et al. Mol Cell Biol. 2007 Sep;27(17):6012-25. doi: 10.1128/MCB.00270-07. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562858 Free PMC article.

54

NODing off and Ramping up.

Abbott DW, Polk DB. Abbott DW, et al. Inflamm Bowel Dis. 2005 Sep;11(9):860-1. doi: 10.1097/01.mib.0000171284.39894.18. Inflamm Bowel Dis. 2005. PMID: 16116322 No abstract available.

55

The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape.

Kang CM, Abbott DW, Park ST, Dascher CC, Cantley LC, Husson RN. Kang CM, et al. Among authors: abbott dw. Genes Dev. 2005 Jul 15;19(14):1692-704. doi: 10.1101/gad.1311105. Epub 2005 Jun 28. Genes Dev. 2005. PMID: 15985609 Free PMC article.

56

A rapid method for determining protein kinase phosphorylation specificity.

Hutti JE, Jarrell ET, Chang JD, Abbott DW, Storz P, Toker A, Cantley LC, Turk BE. Hutti JE, et al. Among authors: abbott dw. Nat Methods. 2004 Oct;1(1):27-9. doi: 10.1038/nmeth708. Nat Methods. 2004. PMID: 15782149

57

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO.

Abbott DW, Wilkins A, Asara JM, Cantley LC. Abbott DW, et al. Curr Biol. 2004 Dec 29;14(24):2217-27. doi: 10.1016/j.cub.2004.12.032. Curr Biol. 2004. PMID: 15620648 Free article.

58

Cervical cancer screening: from the Papanicolaou smear to the vaccine era.

Crum CP, Abbott DW, Quade BJ. Crum CP, et al. Among authors: abbott dw. J Clin Oncol. 2003 May 15;21(10 Suppl):224s-230s. doi: 10.1200/JCO.2003.01.116. J Clin Oncol. 2003. PMID: 12743139 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Results by year

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

58 results

Results by year

Search Page

Filters

My Custom Filters

Results by year

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

58 results

Results by year