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Gender-related disparities in non-small cell lung cancer.
Paggi MG, Vona R, Abbruzzese C, Malorni W. Paggi MG, et al. Cancer Lett. 2010 Dec 1;298(1):1-8. doi: 10.1016/j.canlet.2010.08.009. Epub 2010 Sep 9. Cancer Lett. 2010. PMID: 20826048 Review.
The human papillomavirus-16 E7 oncoprotein exerts antiapoptotic effects via its physical interaction with the actin-binding protein gelsolin.
Mileo AM, Abbruzzese C, Vico C, Bellacchio E, Matarrese P, Ascione B, Federico A, Della Bianca S, Mattarocci S, Malorni W, Paggi MG. Mileo AM, et al. Carcinogenesis. 2013 Oct;34(10):2424-33. doi: 10.1093/carcin/bgt192. Epub 2013 Jun 1. Carcinogenesis. 2013. PMID: 23729654
Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy.
Talarico C, D'Antona L, Scumaci D, Barone A, Gigliotti F, Fiumara CV, Dattilo V, Gallo E, Visca P, Ortuso F, Abbruzzese C, Botta L, Schenone S, Cuda G, Alcaro S, Bianco C, Lavia P, Paggi MG, Perrotti N, Amato R. Talarico C, et al. Oncotarget. 2015 Nov 10;6(35):37511-25. doi: 10.18632/oncotarget.5527. Oncotarget. 2015. PMID: 26462020 Free PMC article.
SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.
Talarico C, Dattilo V, D'Antona L, Barone A, Amodio N, Belviso S, Musumeci F, Abbruzzese C, Bianco C, Trapasso F, Schenone S, Alcaro S, Ortuso F, Florio T, Paggi MG, Perrotti N, Amato R. Talarico C, et al. Oncotarget. 2016 Mar 29;7(13):15868-84. doi: 10.18632/oncotarget.7520. Oncotarget. 2016. PMID: 26908461 Free PMC article.
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