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The microbiota metabolite, phloroglucinol, confers long-term protection against inflammation.
Castelo J, Araujo-Aris S, Barriales D, Tanner Pasco S, Seoane I, Peña-Cearra A, Palacios A, Simó C, Garcia-Cañas V, Khamwong M, Martín-Ruiz I, Gonzalez-Lopez M, Barcena L, Martín Rodríguez JE, Lavín JL, Gutiez N, Marcos R, Atondo E, Cobela A, Plaza-Vinuesa L, Plata A, Santos-Fernandez E, Fernandez-Tejada A, Villarán MC, Mancheño JM, Maria Flores J, María Aransay A, Pellón A, de Las Rivas B, Muñoz R, Margolles A, Ruas-Madiedo P, Victoria Selma M, Gomez de Agüero M, Abecia L, Anguita J, Rodríguez H. Castelo J, et al. Among authors: abecia l. Gut Microbes. 2024 Jan-Dec;16(1):2438829. doi: 10.1080/19490976.2024.2438829. Epub 2024 Dec 15. Gut Microbes. 2024. PMID: 39676480 Free PMC article.
Challenge Specific Modulation of Responses to Adjuvant-Induced Innate Immune Memory.
Pasco ST, Martín-Ruiz I, Araujo-Aris S, Barriales D, Castelo J, Egia-Mendikute L, Gonzalez M, Martin JE, Molina E, Mugica M, Palacios A, Seoane I, Gutiez N, Atondo E, Fernández ES, Oyanguren M, Jimenez-Lasheras B, Peña-Cearra A, Aransay AM, Palazon A, Pellón A, Abecia L, Rodriguez H, Elguezabal N, Anguita J. Pasco ST, et al. Among authors: abecia l. Immunology. 2025 Oct 1. doi: 10.1111/imm.70047. Online ahead of print. Immunology. 2025. PMID: 41034176
The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent.
Goikoetxea-Usandizaga N, Bravo M, Egia-Mendikute L, Abecia L, Serrano-Maciá M, Urdinguio RG, Clos-García M, Rodríguez-Agudo R, Araujo-Legido R, López-Bermudo L, Delgado TC, Lachiondo-Ortega S, González-Recio I, Gil-Pitarch C, Peña-Cearra A, Simón J, Benedé-Ubieto R, Ariño S, Herranz JM, Azkargorta M, Salazar-Bermeo J, Martí N, Varela-Rey M, Falcón-Pérez JM, Lorenzo Ó, Nogueiras R, Elortza F, Nevzorova YA, Cubero FJ, Saura D, Martínez-Cruz LA, Sabio G, Palazón A, Sancho-Bru P, Elguezabal N, Fraga MF, Ávila MA, Bataller R, Marín JJG, Martín F, Martínez-Chantar ML. Goikoetxea-Usandizaga N, et al. Among authors: abecia l. Hepatology. 2023 Sep 1;78(3):878-895. doi: 10.1097/HEP.0000000000000303. Epub 2023 Feb 9. Hepatology. 2023. PMID: 36745935 Free PMC article.
Mitochondrial Dysfunction: Unraveling the Elusive Biology Behind Anti-TNF Response During Ulcerative Colitis.
Kioroglou D, Peña-Cearra A, Corraliza AM, Seoane I, Castelo J, Panés J, Gómez-Irwin L, Rodríguez-Lago I, Ortiz de Zarate J, Fuertes M, Martín-Ruiz I, Gonzalez M, Aransay AM, Salas A, Rodríguez H, Anguita J, Abecia L, Marigorta UM. Kioroglou D, et al. Among authors: abecia l. Inflamm Bowel Dis. 2025 May 12;31(5):1366-1379. doi: 10.1093/ibd/izaf015. Inflamm Bowel Dis. 2025. PMID: 39946175 Free PMC article.
Akkermansia muciniphila-induced trained immune phenotype increases bacterial intracellular survival and attenuates inflammation.
Peña-Cearra A, Palacios A, Pellon A, Castelo J, Pasco ST, Seoane I, Barriales D, Martin JE, Pascual-Itoiz MÁ, Gonzalez-Lopez M, Martín-Ruiz I, Macías-Cámara N, Gutiez N, Araujo-Aris S, Aransay AM, Rodríguez H, Anguita J, Abecia L. Peña-Cearra A, et al. Among authors: abecia l. Commun Biol. 2024 Feb 16;7(1):192. doi: 10.1038/s42003-024-05867-6. Commun Biol. 2024. PMID: 38365881 Free PMC article.
Mitochondrial dysfunction-associated microbiota establishes a transmissible refractory response to anti-TNF therapy during ulcerative colitis.
Peña-Cearra A, Castelo J, Lavín JL, Gonzalez-Lopez M, Pascual-Itoiz MA, Fuertes M, Gutiérrez de Juan V, Bárcena L, Martín-Ruiz I, Pellón A, Seoane I, Barriales D, Palacios A, Fullaondo A, Rodríguez-Lago I, Martinez-Chantar ML, Aransay AM, Rodriguez H, Anguita J, Abecia L. Peña-Cearra A, et al. Among authors: abecia l. Gut Microbes. 2023 Dec;15(2):2266626. doi: 10.1080/19490976.2023.2266626. Epub 2023 Oct 16. Gut Microbes. 2023. PMID: 37842919 Free PMC article.
Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression.
Peña-Cearra A, Song D, Castelo J, Palacios A, Lavín JL, Azkargorta M, Elortza F, Fuertes M, Pascual-Itoiz MA, Barriales D, Martín-Ruiz I, Fullaondo A, Aransay AM, Rodríguez H, Palm NW, Anguita J, Abecia L. Peña-Cearra A, et al. Among authors: abecia l. NPJ Biofilms Microbiomes. 2023 Oct 7;9(1):74. doi: 10.1038/s41522-023-00443-y. NPJ Biofilms Microbiomes. 2023. PMID: 37805634 Free PMC article.
76 results