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ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism.
Rashan EH, Bartlett AK, Khana DB, Zhang J, Jain R, Wade G, Abriata LA, Smith AJ, Baker ZN, Cook T, Caldwell A, Chevalier AR, Forny P, Pfleger BF, Peraro MD, Yuan P, Amador-Noguez D, Simcox JA, Pagliarini DJ. Rashan EH, et al. Among authors: bartlett ak. Nat Struct Mol Biol. 2025 Sep;32(9):1622-1632. doi: 10.1038/s41594-025-01596-4. Epub 2025 Jun 19. Nat Struct Mol Biol. 2025. PMID: 40537578 Free PMC article.
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism.
Rashan EH, Bartlett AK, Khana DB, Zhang J, Jain R, Smith AJ, Baker ZN, Cook T, Caldwell A, Chevalier AR, Pfleger BF, Yuan P, Amador-Noguez D, Simcox JA, Pagliarini DJ. Rashan EH, et al. Among authors: bartlett ak. bioRxiv [Preprint]. 2024 Jan 9:2024.01.09.574893. doi: 10.1101/2024.01.09.574893. bioRxiv. 2024. Update in: Nat Struct Mol Biol. 2025 Sep;32(9):1622-1632. doi: 10.1038/s41594-025-01596-4. PMID: 38260250 Free PMC article. Updated. Preprint.
COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells.
Pelosi L, Morbiato L, Burgardt A, Tonello F, Bartlett AK, Guerra RM, Ferizhendi KK, Desbats MA, Rascalou B, Marchi M, Vázquez-Fonseca L, Agosto C, Zanotti G, Roger-Margueritat M, Alcázar-Fabra M, García-Corzo L, Sánchez-Cuesta A, Navas P, Brea-Calvo G, Trevisson E, Wendisch VF, Pagliarini DJ, Salviati L, Pierrel F. Pelosi L, et al. Among authors: bartlett ak. Mol Cell. 2024 Mar 7;84(5):981-989.e7. doi: 10.1016/j.molcel.2024.01.003. Epub 2024 Jan 30. Mol Cell. 2024. PMID: 38295803 Free PMC article.
Identification of a new COQ4 spliceogenic variant causing severe primary coenzyme Q deficiency.
Alcázar-Fabra M, Østergaard E, Fernández-Ayala DJM, Desbats MA, Morbidoni V, Tomás-Gallado L, García-Corzo L, Blanquer-Roselló MDM, Bartlett AK, Sánchez-Cuesta A, Sena L, Cortés-Rodríguez A, Cascajo-Almenara MV, Pagliarini DJ, Trevisson E, Gronborg SW, Brea-Calvo G. Alcázar-Fabra M, et al. Among authors: bartlett ak. Mol Genet Metab Rep. 2024 Dec 14;42:101176. doi: 10.1016/j.ymgmr.2024.101176. eCollection 2025 Mar. Mol Genet Metab Rep. 2024. PMID: 39759098 Free PMC article.
COQ4 is required for the oxidative decarboxylation of the C1 carbon of Coenzyme Q in eukaryotic cells.
Pelosi L, Morbiato L, Burgardt A, Tonello F, Bartlett AK, Guerra RM, Ferizhendi KK, Desbats MA, Rascalou B, Marchi M, Vázquez-Fonseca L, Agosto C, Zanotti G, Roger-Margueritat M, Alcázar-Fabra M, García-Corzo L, Sánchez-Cuesta A, Navas P, Brea-Calvo G, Trevisson E, Wendisch VF, Pagliarini DJ, Salviati L, Pierrel F. Pelosi L, et al. Among authors: bartlett ak. bioRxiv [Preprint]. 2023 Nov 13:2023.11.13.566839. doi: 10.1101/2023.11.13.566839. bioRxiv. 2023. Update in: Mol Cell. 2024 Mar 7;84(5):981-989.e7. doi: 10.1016/j.molcel.2024.01.003. PMID: 38014142 Free PMC article. Updated. Preprint.