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Page 1
Development and application of a PBPK modeling strategy to support antimalarial drug development.
Abla N, Howgate E, Rowland-Yeo K, Dickins M, Bergagnini-Kolev MC, Chen KF, McFeely S, Bonner JJ, Santos LGA, Gobeau N, Burt H, Barter Z, Jones HM, Wesche D, Charman SA, Möhrle JJ, Burrows JN, Almond LM. Abla N, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Sep;12(9):1335-1346. doi: 10.1002/psp4.13013. Epub 2023 Aug 16. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37587640 Free PMC article.
PBPK-Led Assessment of Antimalarial Drug Concentrations in Breastmilk: A Strategy for Optimal Use of Prediction Methods to Guide Decision Making in an Understudied Population.
Almond LM, Abduljalil K, Pansari A, Kusmider B, Jones HM, Rowland Yeo K, Gardner I, Faisal M, Marrast AC, El Gaaloul M, Möhrle JJ, Abla N. Almond LM, et al. Among authors: abla n. CPT Pharmacometrics Syst Pharmacol. 2025 Apr;14(4):738-750. doi: 10.1002/psp4.13311. Epub 2025 Feb 11. CPT Pharmacometrics Syst Pharmacol. 2025. PMID: 39930940 Free PMC article.
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm, phase 2 clinical trial.
Chandiwana N, Kruger C, Johnstone H, Chughlay MF, Ju C, Kim B, Dineka Y, Arbe-Barnes S, Miller R, Owen A, Hill A, Windgassen D, Abla N, Marrast AC, Duparc S, Francois Venter WD. Chandiwana N, et al. Among authors: abla n. EBioMedicine. 2022 Dec;86:104322. doi: 10.1016/j.ebiom.2022.104322. Epub 2022 Nov 1. EBioMedicine. 2022. PMID: 36332361 Free PMC article. Clinical Trial.
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, Aguiar ACC, Angulo-Barturen I, Churchyard A, Baum J, Fernández BC, Fuchs A, Gamo FJ, Guido RVC, Jiménez-Diaz MB, Pereira DB, Rochford R, Roesch C, Sanz LM, Trevitt G, Witkowski B, Wittlin S, Cooper RA, Rosenthal PJ, Sauerwein RW, Schalkwijk J, Hermkens PHH, Bonnert RV, Campo B, Fidock DA, Llinás M, Niles JC, Kooij TWA, Dechering KJ. de Vries LE, et al. Among authors: abla n. Nat Commun. 2022 Apr 20;13(1):2158. doi: 10.1038/s41467-022-29688-5. Nat Commun. 2022. PMID: 35444200 Free PMC article.
31 results