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Page 1
Molecular Dysfunction and Phenotypic Derangement in Diabetic Cardiomyopathy.
Evangelista I, Nuti R, Picchioni T, Dotta F, Palazzuoli A. Evangelista I, et al. Int J Mol Sci. 2019 Jul 2;20(13):3264. doi: 10.3390/ijms20133264. Int J Mol Sci. 2019. PMID: 31269778 Free PMC article. Review.
High glucose concentrations lead to a loss of mitochondrial networks, increased reactive oxygen species (ROS), endothelial nitric oxide synthase (eNOS) activation and a reduction in cGMP production related to protein kinase G (PKG) activity. Current mechanisms enhan …
High glucose concentrations lead to a loss of mitochondrial networks, increased reactive oxygen species (ROS), endothelial nitric oxi …
Role of Amadori-modified nonenzymatically glycated serum proteins in the pathogenesis of diabetic nephropathy.
Cohen MP, Ziyadeh FN. Cohen MP, et al. J Am Soc Nephrol. 1996 Feb;7(2):183-90. doi: 10.1681/ASN.V72183. J Am Soc Nephrol. 1996. PMID: 8785386 Review.
Ample experimental evidence has demonstrated that Amadori-modified serum proteins adversely affect renal glomerular capillary function, structure, and metabolism. Previous studies from the laboratories of this study's authors have shown that human serum containing d …
Ample experimental evidence has demonstrated that Amadori-modified serum proteins adversely affect renal glomerular capillary function, stru …
The postprandial state and risk of cardiovascular disease.
Lefèbvre PJ, Scheen AJ. Lefèbvre PJ, et al. Diabet Med. 1998;15 Suppl 4:S63-8. doi: 10.1002/(sici)1096-9136(1998120)15:4+3.3.co;2-z. Diabet Med. 1998. PMID: 9868996 Review.
Recent studies have shown that excessive postprandial glucose excursions are accompanied by oxidative stress and, less well known, activation of blood coagulation (increase in circulating D-dimers and prothrombin fragments). The mechanisms through which increased po …
Recent studies have shown that excessive postprandial glucose excursions are accompanied by oxidative stress and, less well known, activatio …