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1998 2
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11 results

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Page 1
Nail-patella syndrome.
Witzgall R. Witzgall R. Pflugers Arch. 2017 Aug;469(7-8):927-936. doi: 10.1007/s00424-017-2013-z. Epub 2017 Jul 5. Pflugers Arch. 2017. PMID: 28681095 Review.
The LMX1B gene is expressed in a variety of tissues, and the symptoms are reflected nicely by its expression pattern. LMX1B is essential for dorso-ventral pattern formation in the limbs, for differentiation of the anterior portions of the eyes, for developmen …
The LMX1B gene is expressed in a variety of tissues, and the symptoms are reflected nicely by its expression pattern. LMX1B is essent …
Developmental biology of the upper limb.
Guéro S. Guéro S. Hand Surg Rehabil. 2018 Oct;37(5):265-274. doi: 10.1016/j.hansur.2018.03.007. Epub 2018 Jul 21. Hand Surg Rehabil. 2018. PMID: 30041930 Review.
This gradient is essential to digit identity and numbers. For the dorsoventral differentiation, the signaling center is the dorsal ectoderm, which secretes WNT7A. ...With a better understanding of developmental biology, surgeons should have better insight into congenita
This gradient is essential to digit identity and numbers. For the dorsoventral differentiation, the signaling center is the dorsal ec …
Retinoid-induced limb malformations.
Lee GS, Kochhar DM, Collins MD. Lee GS, et al. Curr Pharm Des. 2004;10(22):2657-99. doi: 10.2174/1381612043383728. Curr Pharm Des. 2004. PMID: 15320736 Review.
During embryogenesis, limb formation is initiated as a budding off from the embryonic lateral body wall. Limb pattern is specified by a series of epithelial-mesenchymal interactions, directing proximodistal, dorsoventral and anteroposterior axes. ...Accumulated evid …
During embryogenesis, limb formation is initiated as a budding off from the embryonic lateral body wall. Limb pattern is specified by …
Dorsoventral patterning of the vertebrate limb: a process governed by multiple events.
Chen H, Johnson RL. Chen H, et al. Cell Tissue Res. 1999 Apr;296(1):67-73. doi: 10.1007/s004410051267. Cell Tissue Res. 1999. PMID: 10199966 Review.
In this review, we detail recent studies which have led to the first molecular insights into dorsoventral vertebrate limb patterning. In keeping with classical experiments which defined ectodermal-mesodermal signaling as an important component of limb bud dorsove
In this review, we detail recent studies which have led to the first molecular insights into dorsoventral vertebrate limb patterni
Manifold functions of the Nail-Patella Syndrome gene Lmx1b in vertebrate development.
Dai JX, Johnson RL, Ding YQ. Dai JX, et al. Dev Growth Differ. 2009 Apr;51(3):241-50. doi: 10.1111/j.1440-169X.2008.01083.x. Epub 2009 Feb 16. Dev Growth Differ. 2009. PMID: 19222527 Review.
The LIM (Lin-1, Isl-1 and Mec-3)-homeodomain transcription factor 1 beta (Lmx1b) is widely expressed in vertebrate embryos, and is implicated in the development of diverse structures such as limbs, kidneys, eyes and brains. LMX1B mutations in humans cause an autosomal domi …
The LIM (Lin-1, Isl-1 and Mec-3)-homeodomain transcription factor 1 beta (Lmx1b) is widely expressed in vertebrate embryos, and is implicate …
Vertebrate limb development and malformations.
Wolpert L. Wolpert L. Pediatr Res. 1999 Sep;46(3):247-54. doi: 10.1203/00006450-199909000-00001. Pediatr Res. 1999. PMID: 10473037 Review.
The limbs develop from small protrusions (the limb buds) that arise from the body wall of the embryo. ...Hox genes that are transcription factors are expressed both along the body axis and in a complex pattern in the limb and may record positional value. Human mutat …
The limbs develop from small protrusions (the limb buds) that arise from the body wall of the embryo. ...Hox genes that are transcrip …
Genetics of limb development and congenital hand malformations.
Zguricas J, Bakker WF, Heus H, Lindhout D, Heutink P, Hovius SE. Zguricas J, et al. Plast Reconstr Surg. 1998 Apr;101(4):1126-35. doi: 10.1097/00006534-199804040-00039. Plast Reconstr Surg. 1998. PMID: 9514351 Review.
Most of the available information on limb development and patterning has come from studies carried out in the lower vertebrates. ...In this paper, we present an overview of the genetic factors involved in limb development, followed by summarized discoveries in the genetics …
Most of the available information on limb development and patterning has come from studies carried out in the lower vertebrates. ...I …
Nail-patella syndrome. Overview on clinical and molecular findings.
Bongers EM, Gubler MC, Knoers NV. Bongers EM, et al. Pediatr Nephrol. 2002 Sep;17(9):703-12. doi: 10.1007/s00467-002-0911-5. Epub 2002 Jul 30. Pediatr Nephrol. 2002. PMID: 12215822 Review.
The gene underlying NPS, LMX1B, is a LIM-homeodomain transcription factor involved in normal patterning of the dorsoventral axis of the limb during development and early morphogenesis of the glomerular basement membrane. ...
The gene underlying NPS, LMX1B, is a LIM-homeodomain transcription factor involved in normal patterning of the dorsoventral ax …
Human syndromes with congenital patellar anomalies and the underlying gene defects.
Bongers EM, van Kampen A, van Bokhoven H, Knoers NV. Bongers EM, et al. Clin Genet. 2005 Oct;68(4):302-19. doi: 10.1111/j.1399-0004.2005.00508.x. Clin Genet. 2005. PMID: 16143015 Review.
Genetic disorders characterized by congenital patellar aplasia or hypoplasia belong to a clinically diverse and genetically heterogeneous group of lower limb malformations. Patella development involves different molecular and cellular mechanisms regulating dorso-ventral …
Genetic disorders characterized by congenital patellar aplasia or hypoplasia belong to a clinically diverse and genetically heterogen …
[Dorso-ventral patterning of the vertebrate limb and dermatoglyphs with special reference to the pad pattern of mice].
Tsugane MH, Yasuda M. Tsugane MH, et al. Kaibogaku Zasshi. 1998 Dec;73(6):699-708. Kaibogaku Zasshi. 1998. PMID: 9990207 Review. Japanese.
So pad pattern is useful to detect and describe anomalies even in the limbs without skeletal defects. The process of pad development is associated with the limb patterning, and abnormal pad pattern may indicate pathogenesis of abnormal li …
So pad pattern is useful to detect and describe anomalies even in the limbs without skeletal defects. The process of pad devel …
11 results