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1974 1
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2001 2
2002 4
2003 2
2004 4
2005 4
2006 6
2007 4
2008 3
2009 7
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160 results

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Page 1
The effect of iron deficiency and anaemia on women's health.
Benson CS, Shah A, Stanworth SJ, Frise CJ, Spiby H, Lax SJ, Murray J, Klein AA. Benson CS, et al. Anaesthesia. 2021 Apr;76 Suppl 4:84-95. doi: 10.1111/anae.15405. Anaesthesia. 2021. PMID: 33682105 Free article. Review.
Iron deficiency and anaemia during pregnancy are associated with adverse maternal and fetal outcomes, including neurocognitive deficits in children born to iron-deficient mothers. ...Improvements in our understanding of iron homeostasis and the develop
Iron deficiency and anaemia during pregnancy are associated with adverse maternal and fetal outcomes, including neurocognitive defici
Targeting ferroptosis opens new avenues for the development of novel therapeutics.
Sun S, Shen J, Jiang J, Wang F, Min J. Sun S, et al. Signal Transduct Target Ther. 2023 Sep 21;8(1):372. doi: 10.1038/s41392-023-01606-1. Signal Transduct Target Ther. 2023. PMID: 37735472 Free PMC article. Review.
Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics, including altered iron homeostasis, reduced defense against oxidative stress, and abnormal lipid peroxidation. ...
Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics, including altered iron homeost
Overview of iron metabolism in health and disease.
Dev S, Babitt JL. Dev S, et al. Hemodial Int. 2017 Jun;21 Suppl 1(Suppl 1):S6-S20. doi: 10.1111/hdi.12542. Epub 2017 Mar 15. Hemodial Int. 2017. PMID: 28296010 Free PMC article. Review.
Abnormalities in systemic iron balance are common in patients with chronic kidney disease and iron administration is a mainstay of anemia management in many patients. This review provides an overview of the essential role of iron in biology, the regula
Abnormalities in systemic iron balance are common in patients with chronic kidney disease and iron administration is a
Hereditary Hemochromatosis: Rapid Evidence Review.
Kane SF, Roberts C, Paulus R. Kane SF, et al. Am Fam Physician. 2021 Sep 1;104(3):263-270. Am Fam Physician. 2021. PMID: 34523883 Free article. Review.
Hereditary hemochromatosis is an autosomal recessive disorder that disrupts iron homeostasis, resulting in systemic iron overload. It is the most common inherited disorder among people of northern European ancestry. ...Phlebotomy is the mainstay of treatment …
Hereditary hemochromatosis is an autosomal recessive disorder that disrupts iron homeostasis, resulting in systemic iron
The role of iron in brain ageing and neurodegenerative disorders.
Ward RJ, Zucca FA, Duyn JH, Crichton RR, Zecca L. Ward RJ, et al. Lancet Neurol. 2014 Oct;13(10):1045-60. doi: 10.1016/S1474-4422(14)70117-6. Lancet Neurol. 2014. PMID: 25231526 Free PMC article. Review.
Abnormal iron homoeostasis can induce cellular damage through hydroxyl radical production, which can cause the oxidation and modification of lipids, proteins, carbohydrates, and DNA. ...In various neurodegenerative diseases, such as Alzheimer's disease and Pa
Abnormal iron homoeostasis can induce cellular damage through hydroxyl radical production, which can cause the oxidatio
Targetting ferroptosis for blood cell-related diseases.
Chen Z, Jiang J, Fu N, Chen L. Chen Z, et al. J Drug Target. 2022 Mar;30(3):244-258. doi: 10.1080/1061186X.2021.1971237. Epub 2021 Aug 31. J Drug Target. 2022. PMID: 34415804 Review.
Ferroptosis is an iron-dependent cell death pathway and participates in various diseases. ...This paper aims to elaborate the role of ferroptosis in blood cells and related diseases. First, abnormal ferroptosis damages the developing red blood cells by breaking syst …
Ferroptosis is an iron-dependent cell death pathway and participates in various diseases. ...This paper aims to elaborate the role of …
SGLT2 inhibitors: role in protective reprogramming of cardiac nutrient transport and metabolism.
Packer M. Packer M. Nat Rev Cardiol. 2023 Jul;20(7):443-462. doi: 10.1038/s41569-022-00824-4. Epub 2023 Jan 6. Nat Rev Cardiol. 2023. PMID: 36609604 Review.
These by-products trigger downregulation of cytoprotective nutrient-deprivation pathways, thereby promoting cellular stress and undermining cellular survival. SGLT2 inhibitors restore cellular homeostasis through three complementary mechanisms: they might bind directly to …
These by-products trigger downregulation of cytoprotective nutrient-deprivation pathways, thereby promoting cellular stress and undermining …
Iron, Neuroinflammation and Neurodegeneration.
Ward RJ, Dexter DT, Crichton RR. Ward RJ, et al. Int J Mol Sci. 2022 Jun 30;23(13):7267. doi: 10.3390/ijms23137267. Int J Mol Sci. 2022. PMID: 35806270 Free PMC article. Review.
The pro-inflammatory cytokines will induce changes in the iron proteins responsible for maintaining iron homeostasis, such that increased amounts of iron will be deposited in cells in the brain. ...This underlies the importance of ensuring that iron
The pro-inflammatory cytokines will induce changes in the iron proteins responsible for maintaining iron homeostasis, s …
Metabolic surgery and iron homeostasis.
Benotti PN, Wood GC, Still CD, Gerhard GS, Rolston DD, Bistrian BR. Benotti PN, et al. Obes Rev. 2019 Apr;20(4):612-620. doi: 10.1111/obr.12811. Epub 2018 Dec 27. Obes Rev. 2019. PMID: 30589498 Review.
Abnormalities in iron nutrition predisposing to deficiency are common in severely obese patients, and the low-grade systemic inflammation, also common to these patients, reduces the effectiveness of oral iron supplementation. The surgical procedures result in
Abnormalities in iron nutrition predisposing to deficiency are common in severely obese patients, and the low-grade systemic i
Iron Homeostasis Disorder and Alzheimer's Disease.
Peng Y, Chang X, Lang M. Peng Y, et al. Int J Mol Sci. 2021 Nov 18;22(22):12442. doi: 10.3390/ijms222212442. Int J Mol Sci. 2021. PMID: 34830326 Free PMC article. Review.
Although there is a strict regulation mechanism for iron homeostasis in the human body and brain, it is usually inevitably disturbed by genetic and environmental factors, or disordered with aging, which leads to iron metabolism diseases, including many neurod …
Although there is a strict regulation mechanism for iron homeostasis in the human body and brain, it is usually inevitably dis …
160 results