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Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs.
Haddad Momeni M, Fredslund F, Bissaro B, Raji O, Vuong TV, Meier S, Nielsen TS, Lombard V, Guigliarelli B, Biaso F, Haon M, Grisel S, Henrissat B, Welner DH, Master ER, Berrin JG, Abou Hachem M. Haddad Momeni M, et al. Among authors: abou hachem m. Nat Commun. 2021 Apr 9;12(1):2132. doi: 10.1038/s41467-021-22372-0. Nat Commun. 2021. PMID: 33837197 Free PMC article.
An ATP Binding Cassette Transporter Mediates the Uptake of α-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.
Ejby M, Fredslund F, Andersen JM, Vujičić Žagar A, Henriksen JR, Andersen TL, Svensson B, Slotboom DJ, Abou Hachem M. Ejby M, et al. Among authors: abou hachem m. J Biol Chem. 2016 Sep 16;291(38):20220-31. doi: 10.1074/jbc.M116.746529. Epub 2016 Aug 8. J Biol Chem. 2016. PMID: 27502277 Free PMC article.
Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways.
Pichler MJ, Yamada C, Shuoker B, Alvarez-Silva C, Gotoh A, Leth ML, Schoof E, Katoh T, Sakanaka M, Katayama T, Jin C, Karlsson NG, Arumugam M, Fushinobu S, Abou Hachem M. Pichler MJ, et al. Among authors: abou hachem m. Nat Commun. 2020 Jul 3;11(1):3285. doi: 10.1038/s41467-020-17075-x. Nat Commun. 2020. PMID: 32620774 Free PMC article.
62 results