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The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cells in patients with multiple myeloma.
Peled A, Abraham M, Avivi I, Rowe JM, Beider K, Wald H, Tiomkin L, Ribakovsky L, Riback Y, Ramati Y, Aviel S, Galun E, Shaw HL, Eizenberg O, Hardan I, Shimoni A, Nagler A. Peled A, et al. Among authors: abraham m. Clin Cancer Res. 2014 Jan 15;20(2):469-79. doi: 10.1158/1078-0432.CCR-13-1302. Epub 2013 Nov 18. Clin Cancer Res. 2014. PMID: 24246358 Clinical Trial.
Interaction between CXCR4 and CCL20 pathways regulates tumor growth.
Beider K, Abraham M, Begin M, Wald H, Weiss ID, Wald O, Pikarsky E, Abramovitch R, Zeira E, Galun E, Nagler A, Peled A. Beider K, et al. Among authors: abraham m. PLoS One. 2009;4(4):e5125. doi: 10.1371/journal.pone.0005125. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340288 Free PMC article.
1,270 results