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209 results
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PI 3-kinase related kinases: 'big' players in stress-induced signaling pathways.
Abraham RT. Abraham RT. DNA Repair (Amst). 2004 Aug-Sep;3(8-9):883-7. doi: 10.1016/j.dnarep.2004.04.002. DNA Repair (Amst). 2004. PMID: 15279773 Review.
Cell cycle checkpoint signaling through the ATM and ATR kinases.
Abraham RT. Abraham RT. Genes Dev. 2001 Sep 1;15(17):2177-96. doi: 10.1101/gad.914401. Genes Dev. 2001. PMID: 11544175 Review. No abstract available.
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.
Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, Elledge SJ, Abraham RT. Tibbetts RS, et al. Among authors: abraham rt. Genes Dev. 2000 Dec 1;14(23):2989-3002. doi: 10.1101/gad.851000. Genes Dev. 2000. PMID: 11114888 Free PMC article.
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses.
Bao S, Tibbetts RS, Brumbaugh KM, Fang Y, Richardson DA, Ali A, Chen SM, Abraham RT, Wang XF. Bao S, et al. Among authors: abraham rt. Nature. 2001 Jun 21;411(6840):969-74. doi: 10.1038/35082110. Nature. 2001. PMID: 11418864
A role for ATR in the DNA damage-induced phosphorylation of p53.
Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, Shieh SY, Taya Y, Prives C, Abraham RT. Tibbetts RS, et al. Among authors: abraham rt. Genes Dev. 1999 Jan 15;13(2):152-7. doi: 10.1101/gad.13.2.152. Genes Dev. 1999. PMID: 9925639 Free PMC article.
mTOR as a positive regulator of tumor cell responses to hypoxia.
Abraham RT. Abraham RT. Curr Top Microbiol Immunol. 2004;279:299-319. doi: 10.1007/978-3-642-18930-2_18. Curr Top Microbiol Immunol. 2004. PMID: 14560965 Review.
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang TH, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-KaƧmaz K. Kemp MG, et al. Among authors: abraham rt. J Biol Chem. 2010 May 28;285(22):16562-71. doi: 10.1074/jbc.M110.110304. Epub 2010 Mar 15. J Biol Chem. 2010. PMID: 20233725 Free PMC article.
The FRB domain of mTOR: NMR solution structure and inhibitor design.
Leone M, Crowell KJ, Chen J, Jung D, Chiang GG, Sareth S, Abraham RT, Pellecchia M. Leone M, et al. Among authors: abraham rt. Biochemistry. 2006 Aug 29;45(34):10294-302. doi: 10.1021/bi060976+. Biochemistry. 2006. PMID: 16922504
Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation.
Ali A, Zhang J, Bao S, Liu I, Otterness D, Dean NM, Abraham RT, Wang XF. Ali A, et al. Among authors: abraham rt. Genes Dev. 2004 Feb 1;18(3):249-54. doi: 10.1101/gad.1176004. Genes Dev. 2004. PMID: 14871926 Free PMC article.
Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold.
Knight ZA, Chiang GG, Alaimo PJ, Kenski DM, Ho CB, Coan K, Abraham RT, Shokat KM. Knight ZA, et al. Among authors: abraham rt. Bioorg Med Chem. 2004 Sep 1;12(17):4749-59. doi: 10.1016/j.bmc.2004.06.022. Bioorg Med Chem. 2004. PMID: 15358300
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