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Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.
Zhao J, Lee MC, Momin A, Cendan CM, Shepherd ST, Baker MD, Asante C, Bee L, Bethry A, Perkins JR, Nassar MA, Abrahamsen B, Dickenson A, Cobb BS, Merkenschlager M, Wood JN. Zhao J, et al. Among authors: Abrahamsen B. J Neurosci. 2010 Aug 11;30(32):10860-71. doi: 10.1523/JNEUROSCI.1980-10.2010. J Neurosci. 2010. PMID: 20702715 Free PMC article.
Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain.
Abrahamsen B, Schneider N, Erichsen MN, Huynh TH, Fahlke C, Bunch L, Jensen AA. Abrahamsen B, et al. J Neurosci. 2013 Jan 16;33(3):1068-87. doi: 10.1523/JNEUROSCI.3396-12.2013. J Neurosci. 2013. PMID: 23325245 Free PMC article.
Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.
Fricker FR, Zhu N, Tsantoulas C, Abrahamsen B, Nassar MA, Thakur M, Garratt AN, Birchmeier C, McMahon SB, Wood JN, Bennett DL. Fricker FR, et al. Among authors: Abrahamsen B. Version 2. J Neurosci. 2009 Jun 17;29(24):7667-78. doi: 10.1523/JNEUROSCI.6053-08.2009. J Neurosci. 2009. PMID: 19535578 Free PMC article.
A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel Na(V)1.8.
Shao D, Baker MD, Abrahamsen B, Rugiero F, Malik-Hall M, Poon WY, Cheah KS, Yao KM, Wood JN, Okuse K. Shao D, et al. Among authors: Abrahamsen B. Mol Cell Neurosci. 2009 Nov;42(3):219-25. doi: 10.1016/j.mcn.2009.07.003. Epub 2009 Jul 14. Mol Cell Neurosci. 2009. PMID: 19607921 Free PMC article.
VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch.
Lagerström MC, Rogoz K, Abrahamsen B, Persson E, Reinius B, Nordenankar K, Olund C, Smith C, Mendez JA, Chen ZF, Wood JN, Wallén-Mackenzie A, Kullander K. Lagerström MC, et al. Among authors: Abrahamsen B. Neuron. 2010 Nov 4;68(3):529-42. doi: 10.1016/j.neuron.2010.09.016. Neuron. 2010. PMID: 21040852 Free PMC article.
A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain.
Lagerström MC, Rogoz K, Abrahamsen B, Lind AL, Olund C, Smith C, Mendez JA, Wallén-Mackenzie Å, Wood JN, Kullander K. Lagerström MC, et al. Among authors: Abrahamsen B. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5789-94. doi: 10.1073/pnas.1013602108. Epub 2011 Mar 17. Proc Natl Acad Sci U S A. 2011. PMID: 21415372 Free PMC article.
The cell and molecular basis of mechanical, cold, and inflammatory pain.
Abrahamsen B, Zhao J, Asante CO, Cendan CM, Marsh S, Martinez-Barbera JP, Nassar MA, Dickenson AH, Wood JN. Abrahamsen B, et al. Science. 2008 Aug 1;321(5889):702-5. doi: 10.1126/science.1156916. Science. 2008. PMID: 18669863
Ion channel activities implicated in pathological pain.
Wood JN, Abrahamsen B, Baker MD, Boorman JD, Donier E, Drew LJ, Nassar MA, Okuse K, Seereeram A, Stirling CL, Zhao J. Wood JN, et al. Among authors: Abrahamsen B. Novartis Found Symp. 2004;261:32-40; discussion 40-54. Novartis Found Symp. 2004. PMID: 15469043
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