Abramov AY - Search Results

1

Targeting mitochondrial dysfunction in neurodegenerative disease: Part II.

Burchell VS, Gandhi S, Deas E, Wood NW, Abramov AY, Plun-Favreau H. Burchell VS, et al. Among authors: abramov ay. Expert Opin Ther Targets. 2010 May;14(5):497-511. doi: 10.1517/14728221003730434. Expert Opin Ther Targets. 2010. PMID: 20334487 Review.

2

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.

Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, Heales S, Duchen MR, Latchman D, Tabrizi SJ, Wood NW. Wood-Kaczmar A, et al. Among authors: abramov ay. PLoS One. 2008 Jun 18;3(6):e2455. doi: 10.1371/journal.pone.0002455. PLoS One. 2008. PMID: 18560593 Free PMC article.

3

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.

Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, Duchen MR, Abramov AY. Gandhi S, et al. Among authors: abramov ay. Mol Cell. 2009 Mar 13;33(5):627-38. doi: 10.1016/j.molcel.2009.02.013. Mol Cell. 2009. PMID: 19285945 Free PMC article.

4

Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.

Abramov AY, Smulders-Srinivasan TK, Kirby DM, Acin-Perez R, Enriquez JA, Lightowlers RN, Duchen MR, Turnbull DM. Abramov AY, et al. Brain. 2010 Mar;133(Pt 3):797-807. doi: 10.1093/brain/awq015. Epub 2010 Feb 15. Brain. 2010. PMID: 20157008 Free PMC article.

5

Targeting mitochondrial dysfunction in neurodegenerative disease: Part I.

Burchell VS, Gandhi S, Deas E, Wood NW, Abramov AY, Plun-Favreau H. Burchell VS, et al. Among authors: abramov ay. Expert Opin Ther Targets. 2010 Apr;14(4):369-85. doi: 10.1517/14728221003652489. Expert Opin Ther Targets. 2010. PMID: 20184395 Review.

6

Dopamine induces Ca2+ signaling in astrocytes through reactive oxygen species generated by monoamine oxidase.

Vaarmann A, Gandhi S, Abramov AY. Vaarmann A, et al. Among authors: abramov ay. J Biol Chem. 2010 Aug 6;285(32):25018-23. doi: 10.1074/jbc.M110.111450. Epub 2010 Jun 14. J Biol Chem. 2010. PMID: 20547771 Free PMC article.

7

Novel pathway for an old neurotransmitter: dopamine-induced neuronal calcium signalling via receptor-independent mechanisms.

Vaarmann A, Gandhi S, Gourine AV, Abramov AY. Vaarmann A, et al. Among authors: abramov ay. Cell Calcium. 2010 Aug-Sep;48(2-3):176-82. doi: 10.1016/j.ceca.2010.08.008. Epub 2010 Sep 16. Cell Calcium. 2010. PMID: 20846720

8

PINK1 cleavage at position A103 by the mitochondrial protease PARL.

Deas E, Plun-Favreau H, Gandhi S, Desmond H, Kjaer S, Loh SH, Renton AE, Harvey RJ, Whitworth AJ, Martins LM, Abramov AY, Wood NW. Deas E, et al. Among authors: abramov ay. Hum Mol Genet. 2011 Mar 1;20(5):867-79. doi: 10.1093/hmg/ddq526. Epub 2010 Dec 6. Hum Mol Genet. 2011. PMID: 21138942 Free PMC article.

9

Mechanism of neuroprotection of melatonin against beta-amyloid neurotoxicity.

Ionov M, Burchell V, Klajnert B, Bryszewska M, Abramov AY. Ionov M, et al. Among authors: abramov ay. Neuroscience. 2011 Apr 28;180:229-37. doi: 10.1016/j.neuroscience.2011.02.045. Epub 2011 Feb 24. Neuroscience. 2011. PMID: 21354274

10

Bioenergetic consequences of PINK1 mutations in Parkinson disease.

Abramov AY, Gegg M, Grunewald A, Wood NW, Klein C, Schapira AH. Abramov AY, et al. PLoS One. 2011;6(10):e25622. doi: 10.1371/journal.pone.0025622. Epub 2011 Oct 17. PLoS One. 2011. PMID: 22043288 Free PMC article.

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