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Insulin induces a change in extracellular matrix glycoproteins synthesized by rat mesangial cells in culture.
Abrass CK, Spicer D, Raugi GJ. Abrass CK, et al. Kidney Int. 1994 Sep;46(3):613-20. doi: 10.1038/ki.1994.313. Kidney Int. 1994. PMID: 7996784
RNA-binding protein IGF2BP2/IMP2 is required for laminin-β2 mRNA translation and is modulated by glucose concentration.
Schaeffer V, Hansen KM, Morris DR, LeBoeuf RC, Abrass CK. Schaeffer V, et al. Among authors: abrass ck. Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F75-82. doi: 10.1152/ajprenal.00185.2012. Epub 2012 Apr 18. Am J Physiol Renal Physiol. 2012. PMID: 22513850 Free PMC article.
Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A.
Abrass CK, Hansen KM. Abrass CK, et al. J Biol Chem. 2010 Apr 23;285(17):12925-34. doi: 10.1074/jbc.M109.061754. Epub 2010 Feb 18. J Biol Chem. 2010. PMID: 20167606 Free PMC article.
Laminin alpha4-null mutant mice develop chronic kidney disease with persistent overexpression of platelet-derived growth factor.
Abrass CK, Hansen KM, Patton BL. Abrass CK, et al. Am J Pathol. 2010 Feb;176(2):839-49. doi: 10.2353/ajpath.2010.090570. Epub 2009 Dec 24. Am J Pathol. 2010. PMID: 20035058 Free PMC article.
Reductions in laminin beta2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose.
Schaeffer V, Hansen KM, Morris DR, Abrass CK. Schaeffer V, et al. Among authors: abrass ck. Am J Physiol Renal Physiol. 2010 Feb;298(2):F314-22. doi: 10.1152/ajprenal.00483.2009. Epub 2009 Oct 28. Am J Physiol Renal Physiol. 2010. PMID: 19864299 Free PMC article.
IGF-1 induces rat glomerular mesangial cells to accumulate triglyceride.
Berfield AK, Chait A, Oram JF, Zager RA, Johnson AC, Abrass CK. Berfield AK, et al. Among authors: abrass ck. Am J Physiol Renal Physiol. 2006 Jan;290(1):F138-47. doi: 10.1152/ajprenal.00054.2005. Epub 2005 Aug 2. Am J Physiol Renal Physiol. 2006. PMID: 16077083
TG-rich MC foam cells fail to contract in response to angiotensin II (Berfield AK, Andress DL, and Abrass CK. Kidney Int 62: 1229-1237, 2002); however, their migratory response to IGF binding protein-5 is unaffected. ...
TG-rich MC foam cells fail to contract in response to angiotensin II (Berfield AK, Andress DL, and Abrass CK. Kidney Int 62: 1 …
Laminin-8/9 is synthesized by rat glomerular mesangial cells and is required for PDGF-induced mesangial cell migration.
Hansen K, Abrass CK. Hansen K, et al. Among authors: abrass ck. Kidney Int. 2003 Jul;64(1):110-8. doi: 10.1046/j.1523-1755.2003.00039.x. Kidney Int. 2003. PMID: 12787401
IGF-1 induces foam cell formation in rat glomerular mesangial cells.
Berfield AK, Abrass CK. Berfield AK, et al. Among authors: abrass ck. J Histochem Cytochem. 2002 Mar;50(3):395-403. doi: 10.1177/002215540205000310. J Histochem Cytochem. 2002. PMID: 11850441
IGF-1-induced lipid accumulation impairs mesangial cell migration and contractile function.
Berfield AK, Andress DL, Abrass CK. Berfield AK, et al. Among authors: abrass ck. Kidney Int. 2002 Oct;62(4):1229-37. doi: 10.1111/j.1523-1755.2002.kid578.x. Kidney Int. 2002. PMID: 12234293
Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5.
Berfield AK, Hansen KM, Abrass CK. Berfield AK, et al. Among authors: abrass ck. Am J Physiol Cell Physiol. 2006 Oct;291(4):C589-99. doi: 10.1152/ajpcell.00623.2005. Epub 2006 May 3. Am J Physiol Cell Physiol. 2006. PMID: 16672690
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