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Nested expression domains of four homeobox genes in developing rostral brain.
Simeone A, Acampora D, Gulisano M, Stornaiuolo A, Boncinelli E. Simeone A, et al. Among authors: acampora d. Nature. 1992 Aug 20;358(6388):687-90. doi: 10.1038/358687a0. Nature. 1992. PMID: 1353865
Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.
Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A. Di Giovannantonio LG, et al. Among authors: acampora d. Development. 2014 Jan;141(2):377-88. doi: 10.1242/dev.102954. Epub 2013 Dec 11. Development. 2014. PMID: 24335253
Selective inactivation of Otx2 mRNA isoforms reveals isoform-specific requirement for visceral endoderm anteriorization and head morphogenesis and highlights cell diversity in the visceral endoderm.
Acampora D, Di Giovannantonio LG, Di Salvio M, Mancuso P, Simeone A. Acampora D, et al. Mech Dev. 2009 Oct;126(10):882-97. doi: 10.1016/j.mod.2009.07.003. Epub 2009 Jul 15. Mech Dev. 2009. PMID: 19615442
OTX2 restricts entry to the mouse germline.
Zhang J, Zhang M, Acampora D, Vojtek M, Yuan D, Simeone A, Chambers I. Zhang J, et al. Among authors: acampora d. Nature. 2018 Oct;562(7728):595-599. doi: 10.1038/s41586-018-0581-5. Epub 2018 Oct 3. Nature. 2018. PMID: 30283136 Free PMC article.
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency.
Fiorenzano A, Pascale E, D'Aniello C, Acampora D, Bassalert C, Russo F, Andolfi G, Biffoni M, Francescangeli F, Zeuner A, Angelini C, Chazaud C, Patriarca EJ, Fico A, Minchiotti G. Fiorenzano A, et al. Among authors: acampora d. Nat Commun. 2016 Sep 2;7:12589. doi: 10.1038/ncomms12589. Nat Commun. 2016. PMID: 27586544 Free PMC article.
Reorganization of enhancer patterns in transition from naive to primed pluripotency.
Buecker C, Srinivasan R, Wu Z, Calo E, Acampora D, Faial T, Simeone A, Tan M, Swigut T, Wysocka J. Buecker C, et al. Among authors: acampora d. Cell Stem Cell. 2014 Jun 5;14(6):838-53. doi: 10.1016/j.stem.2014.04.003. Cell Stem Cell. 2014. PMID: 24905168 Free PMC article.
Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons.
Panman L, Papathanou M, Laguna A, Oosterveen T, Volakakis N, Acampora D, Kurtsdotter I, Yoshitake T, Kehr J, Joodmardi E, Muhr J, Simeone A, Ericson J, Perlmann T. Panman L, et al. Among authors: acampora d. Cell Rep. 2014 Aug 21;8(4):1018-25. doi: 10.1016/j.celrep.2014.07.016. Epub 2014 Aug 7. Cell Rep. 2014. PMID: 25127144
Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon.
Omodei D, Acampora D, Mancuso P, Prakash N, Di Giovannantonio LG, Wurst W, Simeone A. Omodei D, et al. Among authors: acampora d. Development. 2008 Oct;135(20):3459-70. doi: 10.1242/dev.027003. Development. 2008. PMID: 18820178
Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain.
Puelles E, Acampora D, Lacroix E, Signore M, Annino A, Tuorto F, Filosa S, Corte G, Wurst W, Ang SL, Simeone A. Puelles E, et al. Among authors: acampora d. Nat Neurosci. 2003 May;6(5):453-60. doi: 10.1038/nn1037. Nat Neurosci. 2003. PMID: 12652306
Organizing centers emit signaling molecules that specify different neuronal cell types at precise positions along the anterior-posterior (A-P) and dorsal-ventral (D-V) axes of neural tube during development. ...We propose that this mechanism may provide both A-P and D
Organizing centers emit signaling molecules that specify different neuronal cell types at precise positions along the anterior-posterior (A- …
Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells.
Acampora D, Di Giovannantonio LG, Garofalo A, Nigro V, Omodei D, Lombardi A, Zhang J, Chambers I, Simeone A. Acampora D, et al. Stem Cell Reports. 2017 Nov 14;9(5):1642-1659. doi: 10.1016/j.stemcr.2017.09.019. Epub 2017 Oct 19. Stem Cell Reports. 2017. PMID: 29056334 Free PMC article.
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