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1998 5
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201 results

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Page 1
Pemphigus.
Schmidt E, Kasperkiewicz M, Joly P. Schmidt E, et al. Lancet. 2019 Sep 7;394(10201):882-894. doi: 10.1016/S0140-6736(19)31778-7. Lancet. 2019. PMID: 31498102 Review.
The binding of autoantibodies to Dsg proteins induces a separation of neighbouring keratinocytes, in a process known as acantholysis. The two main pemphigus variants are pemphigus vulgaris, which often originates with painful oral erosions, and pemphigus foliaceus, which i …
The binding of autoantibodies to Dsg proteins induces a separation of neighbouring keratinocytes, in a process known as acantholysis. …
Pemphigus.
Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Payne AS, Amagai M. Kasperkiewicz M, et al. Nat Rev Dis Primers. 2017 May 11;3:17026. doi: 10.1038/nrdp.2017.26. Nat Rev Dis Primers. 2017. PMID: 28492232 Free PMC article. Review.
Pemphigus is a group of IgG-mediated autoimmune diseases of stratified squamous epithelia, such as the skin and oral mucosa, in which acantholysis (the loss of cell adhesion) causes blisters and erosions. ...
Pemphigus is a group of IgG-mediated autoimmune diseases of stratified squamous epithelia, such as the skin and oral mucosa, in which aca
Oral pemphigus.
Giannetti L, Generali L, Bertoldi C. Giannetti L, et al. G Ital Dermatol Venereol. 2018 Jun;153(3):383-388. doi: 10.23736/S0392-0488.18.05887-X. Epub 2018 Mar 6. G Ital Dermatol Venereol. 2018. PMID: 29512980 Review.
The involvement of the oral mucosa in patients affected by pemphigus vulgaris (PV), paraneoplastic, IgA pemphigus, and in some cases iatrogenic pemphigus is common and often a prelude to skin lesions. Intraepidermal bullae are caused by acantholysis, induced by IgG autoant …
The involvement of the oral mucosa in patients affected by pemphigus vulgaris (PV), paraneoplastic, IgA pemphigus, and in some cases iatroge …
[Dyskeratosis follicularis].
Dorf IL, Sommerlund M, Skytte AB, Koppelhus U. Dorf IL, et al. Ugeskr Laeger. 2018 May 7;180(19):V10170720. Ugeskr Laeger. 2018. PMID: 29761773 Free article. Review. Danish.
Mutations in the gene ATP2A2 encoding the Ca2+-ATPase SERCA2 in the endoplasmatic reticulum lead to acantholysis and dyskeratosis in the epidermis, nails and mucosal membranes with resultant brown-yellow coloured, often infested skin papules and nail changes. ...
Mutations in the gene ATP2A2 encoding the Ca2+-ATPase SERCA2 in the endoplasmatic reticulum lead to acantholysis and dyskeratosis in …
Pemphigus, a pathomechanism of acantholysis.
Furue M, Kadono T. Furue M, et al. Australas J Dermatol. 2017 Aug;58(3):171-173. doi: 10.1111/ajd.12562. Epub 2017 Feb 17. Australas J Dermatol. 2017. PMID: 28211055 Review.
The pathogenetic mechanisms of acantholysis due to anti-desmoglein autoantibodies are not fully understood. However, recent studies have revealed that signalling-dependent and signalling-independent pathways are operative in the loss of cell adhesion. In this review, we fo …
The pathogenetic mechanisms of acantholysis due to anti-desmoglein autoantibodies are not fully understood. However, recent studies h …
Pemphigus.
Santoro FA, Stoopler ET, Werth VP. Santoro FA, et al. Dent Clin North Am. 2013 Oct;57(4):597-610. doi: 10.1016/j.cden.2013.06.002. Epub 2013 Aug 12. Dent Clin North Am. 2013. PMID: 24034068 Free PMC article. Review.
These autoimmune blistering disorders have antibodies targeted against proteins of keratinocyte adhesion, thereby causing acantholysis. Clinical findings include oral erosions and flaccid cutaneous bullae and erosions. ...
These autoimmune blistering disorders have antibodies targeted against proteins of keratinocyte adhesion, thereby causing acantholysis
Dowling-Degos disease: a review.
Stephan C, Kurban M, Abbas O. Stephan C, et al. Int J Dermatol. 2021 Aug;60(8):944-950. doi: 10.1111/ijd.15385. Epub 2020 Dec 23. Int J Dermatol. 2021. PMID: 33368260 Review.
The most closely linked entity is Galli-Galli, which is clinically indistinguishable from Dowling-Degos disease and can only be distinguished by the presence of acantholysis on microscopy. Unfortunately, Dowling-Degos disease is generally progressive and recalcitrant to tr …
The most closely linked entity is Galli-Galli, which is clinically indistinguishable from Dowling-Degos disease and can only be distinguishe …
Pemphigus.
Bystryn JC, Rudolph JL. Bystryn JC, et al. Lancet. 2005 Jul 2-8;366(9479):61-73. doi: 10.1016/S0140-6736(05)66829-8. Lancet. 2005. PMID: 15993235 Review.
The disease is diagnosed based on its clinical manifestations (flaccid blisters and erosions on skin and oral mucosa), histology (epidermal acantholysis), and immunological abnormalities (circulating and tissue-fixed antibodies against keratinocyte surface antigens). ...
The disease is diagnosed based on its clinical manifestations (flaccid blisters and erosions on skin and oral mucosa), histology (epidermal …
201 results