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The following terms were not found in PubMed: ingens+Alkaloid+Cytotoxic, activity+Ingenine, F+Tetrahydro-beta-carboline+cytotoxic
Page 1
Ingenine F: A New Cytotoxic Tetrahydro Carboline Alkaloid from the Indonesian Marine Sponge Acanthostrongylophora ingens.
Ibrahim S, Mohamed G, Al Haidari R, El-Kholy A, Zayed M. Ibrahim S, et al. Pharmacogn Mag. 2018 Apr-Jun;14(54):231-234. doi: 10.4103/pm.pm_489_17. Epub 2018 Apr 10. Pharmacogn Mag. 2018. PMID: 29720837 Free PMC article.
BACKGROUND: Marine organisms are established to be a wealthy source of bioactive compounds with diverse chemical structures and bioactivities. Acanthostrongylophora ingens is known to be rich with pyrimidine b-carboline and manzamine-type alkaloids. ...RESULTS: A new 1,2,3 …
BACKGROUND: Marine organisms are established to be a wealthy source of bioactive compounds with diverse chemical structures and bioactivitie …
A Collection of Bioactive Nitrogen-Containing Molecules from the Marine Sponge Acanthostrongylophora ingens.
Esposito G, Mai LH, Longeon A, Mangoni A, Durieu E, Meijer L, Van Soest R, Costantino V, Bourguet-Kondracki ML. Esposito G, et al. Mar Drugs. 2019 Aug 15;17(8):472. doi: 10.3390/md17080472. Mar Drugs. 2019. PMID: 31443260 Free PMC article.
Thirteen nitrogen-containing molecules (1a/1b and 2-12) were isolated from the Indonesian sponge Acanthostrongylophora ingens, highlighting the richness of this organism as a source of alkaloids. ...The most interesting bioactivity result was obtained with the known acanth …
Thirteen nitrogen-containing molecules (1a/1b and 2-12) were isolated from the Indonesian sponge Acanthostrongylophora ingens, highli …
Ingenine E, a new cytotoxic beta-carboline alkaloid from the Indonesian sponge Acanthostrongylophora ingens.
Ibrahim SR, Mohamed GA. Ibrahim SR, et al. J Asian Nat Prod Res. 2017 May;19(5):504-509. doi: 10.1080/10286020.2016.1213723. Epub 2016 Sep 2. J Asian Nat Prod Res. 2017. PMID: 27588456
The cytotoxic activity of the isolated compounds was evaluated toward MCF7, A549, HCT116, PC12, and Hela cancer cell lines. Ingenine E (4) exhibited cytotoxic activity against MCF7, HCT116, and A549 cell lines with IC(50) values of 3.5, 0.67, and 2.15 mug/ml....
The cytotoxic activity of the isolated compounds was evaluated toward MCF7, A549, HCT116, PC12, and Hela cancer cell lines. Ingenine …
Tetradehydrohalicyclamine B, a new proteasome inhibitor from the marine sponge Acanthostrongylophora ingens.
Kato H, El-Desoky AH, Takeishi Y, Nehira T, Angkouw ED, Mangindaan REP, de Voogd NJ, Tsukamoto S. Kato H, et al. Bioorg Med Chem Lett. 2019 Jan 1;29(1):8-10. doi: 10.1016/j.bmcl.2018.11.028. Epub 2018 Nov 14. Bioorg Med Chem Lett. 2019. PMID: 30455150
A new halicyclamine derivative, tetradehydrohalicyclamine B (1), was isolated from the marine sponge Acanthostrongylophora ingens, along with halicyclamine B (2) as proteasome inhibitors. Compound 1 is the second example found to have a pyridinium ring in the halicyclamine …
A new halicyclamine derivative, tetradehydrohalicyclamine B (1), was isolated from the marine sponge Acanthostrongylophora ingens, al …
Neuritogenic activity-guided isolation of a free base form manzamine A from a marine sponge, Acanthostrongylophora aff. ingens (Thiele, 1899).
Zhang B, Higuchi R, Miyamoto T, Van Soest RW. Zhang B, et al. Chem Pharm Bull (Tokyo). 2008 Jun;56(6):866-9. doi: 10.1248/cpb.56.866. Chem Pharm Bull (Tokyo). 2008. PMID: 18520099 Free article.
Two manzamine-class alkaloids, manzamine A (1) and 8-hydroxymanzamine (2) were isolated from a Japanese marine sponge Acanthostrongylophora aff. ingens, together with three known alkaloids manzamine E (3), manzamine F (4), and manzamine X (5). ...These manzamine-class alka …
Two manzamine-class alkaloids, manzamine A (1) and 8-hydroxymanzamine (2) were isolated from a Japanese marine sponge Acanthostrongylopho …
Ingenines A and B, Two New Alkaloids from the Indonesian Sponge Acanthostrongylophora ingens.
Ibrahim SR, Mohamed GA, Zayed MF, Sayed HM. Ibrahim SR, et al. Drug Res (Stuttg). 2015 Jul;65(7):361-5. doi: 10.1055/s-0034-1384577. Epub 2014 Jul 22. Drug Res (Stuttg). 2015. PMID: 25050517
As a continuation of the work on EtOAc fraction of the Indonesian sponge Acanthostrongylophora ingens, 2 new alkaloids: one pyrimidine-beta-carboline alkaloid named ingenine A (2) and one pyrimidine-gamma-carboline alkaloid named ingenine B (3), along with annomontine (1) …
As a continuation of the work on EtOAc fraction of the Indonesian sponge Acanthostrongylophora ingens, 2 new alkaloids: one pyrimidin …
Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge.
Kim CK, Riswanto R, Won TH, Kim H, Elya B, Sim CJ, Oh DC, Oh KB, Shin J. Kim CK, et al. J Nat Prod. 2017 May 26;80(5):1575-1583. doi: 10.1021/acs.jnatprod.7b00121. Epub 2017 Apr 28. J Nat Prod. 2017. PMID: 28452477
Five new manzamine alkaloids (1-5) and new salt forms of two known manzamines (6 and 7), along with seven known compounds (8-14) of the same structural class, were isolated from an Indonesian Acanthostrongylophora sp. sponge. On the basis of the results of combined spectro …
Five new manzamine alkaloids (1-5) and new salt forms of two known manzamines (6 and 7), along with seven known compounds (8-14) of the same …
Acantholactam and pre-neo-kauluamine, manzamine-related alkaloids from the Indonesian marine sponge Acanthostrongylophora ingens.
El-Desoky AH, Kato H, Eguchi K, Kawabata T, Fujiwara Y, Losung F, Mangindaan RE, de Voogd NJ, Takeya M, Yokosawa H, Tsukamoto S. El-Desoky AH, et al. J Nat Prod. 2014 Jun 27;77(6):1536-40. doi: 10.1021/np500290a. Epub 2014 Jun 5. J Nat Prod. 2014. PMID: 24902064
Two new manzamine alkaloids, acantholactam (3) and pre-neo-kauluamine (4), were isolated from the marine sponge Acanthostrongylophora ingens along with manzamine A (1) and neo-kauluamine (2). Acantholactam contains a gamma-lactam ring N-substituted with a (Z)-2-hexenoic ac …
Two new manzamine alkaloids, acantholactam (3) and pre-neo-kauluamine (4), were isolated from the marine sponge Acanthostrongylophora …
Indonesian marine and its medicinal contribution.
Nugraha AS, Firli LN, Rani DM, Hidayatiningsih A, Lestari ND, Wongso H, Tarman K, Rahaweman AC, Manurung J, Ariantari NP, Papu A, Putra MY, Pratama ANW, Wessjohann LA, Keller PA. Nugraha AS, et al. Nat Prod Bioprospect. 2023 Oct 16;13(1):38. doi: 10.1007/s13659-023-00403-1. Nat Prod Bioprospect. 2023. PMID: 37843645 Free PMC article. Review.
Findings with significant pharmacological activities are further discussed through a scoping data collection. This review discusses macroorganisms (Sponges, Ascidian, Gorgonians, Algae, Mangrove) and microorganism (Bacteria and Fungi) and highlights significant discoveries …
Findings with significant pharmacological activities are further discussed through a scoping data collection. This review discusses m …
Bioactive (+)-manzamine A and (+)-8-hydroxymanzamine A tertiary bases and salts from Acanthostrongylophora ingens and their preparations.
Samoylenko V, Khan SI, Jacoba MR, Tekwani BL, Walker LA, Hufford CD, Muhammad I. Samoylenko V, et al. Nat Prod Commun. 2009 Feb;4(2):185-92. Nat Prod Commun. 2009. PMID: 19370920 Free PMC article.
The genus Acanthostrongylophora is famous for producing a wide array of manzamine alkaloids as natural hydrochloride salts. ...Compounds 1, 3 and 4 showed good antimicrobial activities against methicillin-resistant Staphylococcus aureus and Mycobacterium intracellul …
The genus Acanthostrongylophora is famous for producing a wide array of manzamine alkaloids as natural hydrochloride salts. ...Compou …
19 results