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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 5
1965 4
1966 1
1967 4
1968 1
1969 1
1970 7
1971 4
1972 1
1973 4
1975 9
1976 5
1977 11
1978 15
1979 11
1980 20
1981 17
1982 19
1983 25
1984 21
1985 26
1986 37
1987 24
1988 36
1989 42
1990 70
1991 45
1992 56
1993 49
1994 55
1995 50
1996 29
1997 34
1998 30
1999 43
2000 42
2001 28
2002 51
2003 34
2004 48
2005 56
2006 56
2007 52
2008 59
2009 65
2010 65
2011 70
2012 70
2013 86
2014 59
2015 90
2016 87
2017 73
2018 91
2019 91
2020 107
2021 115
2022 110
2023 107
2024 116
2025 98

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2,545 results

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Page 1
L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain.
Ferreira GC, McKenna MC. Ferreira GC, et al. Neurochem Res. 2017 Jun;42(6):1661-1675. doi: 10.1007/s11064-017-2288-7. Epub 2017 May 16. Neurochem Res. 2017. PMID: 28508995 Free PMC article. Review.
In recent years there has been considerable interest in the therapeutic potential of L-carnitine and its acetylated derivative acetyl-L-carnitine (ALCAR) for neuroprotection in a number of disorders including hypoxia-ischemia, traumatic brain injury, Alzheime …
In recent years there has been considerable interest in the therapeutic potential of L-carnitine and its acetylated derivative acetyl …
Acetyl-L-carnitine in chronic pain: A narrative review.
Sarzi-Puttini P, Giorgi V, Di Lascio S, Fornasari D. Sarzi-Puttini P, et al. Pharmacol Res. 2021 Nov;173:105874. doi: 10.1016/j.phrs.2021.105874. Epub 2021 Sep 7. Pharmacol Res. 2021. PMID: 34500063 Review.
Acetyl-L-carnitine (ALC) is an endogenous molecule that not only plays a role in energy metabolism, but also has antioxidant properties, protects from oxidative stress, modulates brain neurotransmitters such as acetylcholine, serotonin and dopamine, and acts …
Acetyl-L-carnitine (ALC) is an endogenous molecule that not only plays a role in energy metabolism, but also has antiox …
Acetyl-L-carnitine for dementia.
Hudson S, Tabet N. Hudson S, et al. Cochrane Database Syst Rev. 2003;2003(2):CD003158. doi: 10.1002/14651858.CD003158. Cochrane Database Syst Rev. 2003. PMID: 12804452 Free PMC article.
Various pathological processes are linked to memory impairment in dementia, particularly those affecting the cholinergic neurotransmitter system. Acetyl-l-carnitine (ALC) is derived from carnitine and is described as having several properties which may be ben …
Various pathological processes are linked to memory impairment in dementia, particularly those affecting the cholinergic neurotransmitter sy …
Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.
Rolim LC, da Silva EM, Flumignan RL, Abreu MM, Dib SA. Rolim LC, et al. Cochrane Database Syst Rev. 2019 Jun 15;6(6):CD011265. doi: 10.1002/14651858.CD011265.pub2. Cochrane Database Syst Rev. 2019. PMID: 31201734 Free PMC article.
Strategies that support peripheral nerve regeneration and restore neurological function in people with painful or painless DPN are needed. The amino acid acetyl-L-carnitine (ALC) plays a role in the transfer of long-chain fatty acids into mitochondria for bet …
Strategies that support peripheral nerve regeneration and restore neurological function in people with painful or painless DPN are needed. T …
Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update.
Pennisi M, Lanza G, Cantone M, D'Amico E, Fisicaro F, Puglisi V, Vinciguerra L, Bella R, Vicari E, Malaguarnera G. Pennisi M, et al. Nutrients. 2020 May 12;12(5):1389. doi: 10.3390/nu12051389. Nutrients. 2020. PMID: 32408706 Free PMC article. Review.
Several studies explored the effects of acetyl-L-carnitine (ALC) in dementia, suggesting a role in slowing down cognitive decline. ...
Several studies explored the effects of acetyl-L-carnitine (ALC) in dementia, suggesting a role in slowing down cogniti …
Acetyl-L-carnitine and Amyotrophic Lateral Sclerosis: Current Evidence and Potential use.
De Marchi F, Venkatesan S, Saraceno M, Mazzini L, Grossini E. De Marchi F, et al. CNS Neurol Disord Drug Targets. 2024;23(5):588-601. doi: 10.2174/1871527322666230330083757. CNS Neurol Disord Drug Targets. 2024. PMID: 36998125 Review.
RESULTS: In this context, using agents, like acetyl L-carnitine (ALCAR), provides mitochondrial support, reduces oxidative stress, and improves synaptic transmission. ...
RESULTS: In this context, using agents, like acetyl L-carnitine (ALCAR), provides mitochondrial support, reduces oxidat …
Acetyl-L-carnitine in hepatic encephalopathy.
Malaguarnera M. Malaguarnera M. Metab Brain Dis. 2013 Jun;28(2):193-9. doi: 10.1007/s11011-013-9376-4. Epub 2013 Feb 8. Metab Brain Dis. 2013. PMID: 23389620 Review.
In fact, Acetyl-L-carnitine induces ureagenesis leading to decreased blood and brain ammonia levels. Acetyl-L-carnitine treatment decreases the severity of mental and physical fatigue, depression cognitive impairment and improves health-r …
In fact, Acetyl-L-carnitine induces ureagenesis leading to decreased blood and brain ammonia levels. Acetyl-L …
Acetyl-L-carnitine.
[No authors listed] [No authors listed] Altern Med Rev. 1999 Dec;4(6):438-41. Altern Med Rev. 1999. PMID: 10608918
Acetyl-L-carnitine (ALC) is an ester of the trimethylated amino acid, L-carnitine, and is synthesized in the human brain, liver, and kidney by the enzyme ALC-transferase. Acetyl-L-carnitine facilitates the uptake of acetyl CoA into the mi …
Acetyl-L-carnitine (ALC) is an ester of the trimethylated amino acid, L-carnitine, and is synthesized in the human brai …
L-carnitine and Acetyl-L Carnitine: A Possibility for Treating Alterations Induced by Obesity in the Central Nervous System.
da Silva LE, de Oliveira MP, da Silva MR, Abel JDS, Tartari G, de Aguiar da Costa M, Ludvig Gonçalves C, Rezin GT. da Silva LE, et al. Neurochem Res. 2023 Nov;48(11):3316-3326. doi: 10.1007/s11064-023-04000-z. Epub 2023 Jul 27. Neurochem Res. 2023. PMID: 37495838 Review.
In this sense, searching for new therapeutic alternatives for reestablishing metabolic homeostasis is necessary. L-carnitine (LC) and acetyl-L-carnitine (LAC) have neuroprotective effects against oxidative stress and mitochondrial dysfunction in several condi …
In this sense, searching for new therapeutic alternatives for reestablishing metabolic homeostasis is necessary. L-carnitine (LC) and ace …
Effects of acetyl-L-carnitine in diabetic neuropathy and other geriatric disorders.
Sergi G, Pizzato S, Piovesan F, Trevisan C, Veronese N, Manzato E. Sergi G, et al. Aging Clin Exp Res. 2018 Feb;30(2):133-138. doi: 10.1007/s40520-017-0770-3. Epub 2017 May 22. Aging Clin Exp Res. 2018. PMID: 28534301 Review.
A long history of diabetes mellitus and increasing age are associated with the onset of diabetic neuropathy, a painful and highly disabling complication with a prevalence peaking at 50% among elderly diabetic patients. Acetyl-L-carnitine (ALC) is a molecule d …
A long history of diabetes mellitus and increasing age are associated with the onset of diabetic neuropathy, a painful and highly disabling …
2,545 results