Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1987 1
1988 1
1990 1
1998 1
1999 1
2003 1
2004 1
2005 1
2006 2
2007 1
2008 1
2009 3
2010 1
2011 4
2012 6
2013 2
2014 4
2015 5
2016 4
2017 5
2018 3
2019 7
2020 4
2021 1
2022 1
2023 4
2024 1
2025 5
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

64 results

Results by year

Filters applied: . Clear all
The following terms were not found in PubMed: inhibition+Alzheimer's, disease+Asiaticoside, Withanolide-A+high-performance, quantification+Piperine+Alzheimer's
Page 1
Research Advances and Detection Methodologies for Microbe-Derived Acetylcholinesterase Inhibitors: A Systemic Review.
Su J, Liu H, Guo K, Chen L, Yang M, Chen Q. Su J, et al. Molecules. 2017 Jan 23;22(1):176. doi: 10.3390/molecules22010176. Molecules. 2017. PMID: 28125001 Free PMC article.
Acetylcholinesterase inhibitors (AChEIs) are an attractive research subject owing to their potential applications in the treatment of neurodegenerative diseases. ...Their active ingredients of fermentation products include alkaloids, terpenoids, phenylpropanoids, an
Acetylcholinesterase inhibitors (AChEIs) are an attractive research subject owing to their potential applications in the treatment of
Perilla frutescens Extract Ameliorates Acetylcholinesterase and Trimethyltin Chloride-Induced Neurotoxicity.
Choi SJ, Oh SS, Kim CR, Kwon YK, Suh SH, Kim JK, Park GG, Son SY, Shin DH. Choi SJ, et al. J Med Food. 2016 Mar;19(3):281-9. doi: 10.1089/jmf.2015.3540. Epub 2015 Oct 27. J Med Food. 2016. PMID: 26505950
One of the critical features of Alzheimer's disease is cognitive dysfunction, which is, in part, due to decreases in acetylcholine (ACh). ...To isolate the active compound from the P. frutescens extract, solvent partitioning, silica gel open column chromatography
One of the critical features of Alzheimer's disease is cognitive dysfunction, which is, in part, due to decreases in acetylcho …
Effect directed analysis and TLC screening of Schisandra chinensis fruits.
Sobstyl E, Szopa A, Ekiert H, Gnat S, Typek R, Choma IM. Sobstyl E, et al. J Chromatogr A. 2020 May 10;1618:460942. doi: 10.1016/j.chroma.2020.460942. Epub 2020 Feb 3. J Chromatogr A. 2020. PMID: 32057448
S. chinensis is also known for its adaptogenic properties which can support the treatment of neurodegenerative disorders, particularly Alzheimer's disease. The components of S. chinensis have been analyzed mostly using chromatography, including HPLC, GC and T …
S. chinensis is also known for its adaptogenic properties which can support the treatment of neurodegenerative disorders, particularly Alzhe …
Phytochemical Characterization and Assessment of Antioxidant and Anti-Alzheimer Effects of Algerian Seseli Tortuosum.
Slimani A, Akkal W, Acheraf Benmekhbi A, Mosbah A, Selim Cakmak Y, Lefahal M, Bousetla A, Mokrani EH, Bensouici C, Laouer H, Akkal S, Nieto G. Slimani A, et al. Chem Biodivers. 2025 Jan;22(1):e202400482. doi: 10.1002/cbdv.202400482. Epub 2024 Nov 19. Chem Biodivers. 2025. PMID: 39287103 Free PMC article.
HPLC analysis, phytochemical screening, thin layer chromatography, polyphenols and flavonoid contents were conducted to determine the bioactive contents of the Algerian Seseli tortuosum plant. ...
HPLC analysis, phytochemical screening, thin layer chromatography, polyphenols and flavonoid contents were conducted to …
Production and enhancement of the acetylcholinesterase inhibitor, huperzine A, from an endophytic Alternaria brassicae AGF041.
Zaki AG, El-Shatoury EH, Ahmed AS, Al-Hagar OEA. Zaki AG, et al. Appl Microbiol Biotechnol. 2019 Jul;103(14):5867-5878. doi: 10.1007/s00253-019-09897-7. Epub 2019 May 22. Appl Microbiol Biotechnol. 2019. PMID: 31119352
Huperzine A (HupA) is a potent acetylcholinesterase (AChE) inhibitor of a great consideration as a prospective drug candidate for Alzheimer's disease treatment. ...
Huperzine A (HupA) is a potent acetylcholinesterase (AChE) inhibitor of a great consideration as a prospective drug candidate for Alz …
Potent Acetylcholinesterase Selective and Reversible Homodimeric Agent Based on Tacrine for Theranostics.
Meena VK, Chaturvedi S, Sharma RK, Mishra AK, Hazari PP. Meena VK, et al. Mol Pharm. 2019 Jun 3;16(6):2296-2308. doi: 10.1021/acs.molpharmaceut.8b01058. Epub 2019 May 15. Mol Pharm. 2019. PMID: 31059278
Acetylcholinesterase (AChE) has been an important biomarker for diagnosing Alzheimer's disease (AD), due to reduction in AChE activity in post-mortem brains of AD patients. ...
Acetylcholinesterase (AChE) has been an important biomarker for diagnosing Alzheimer's disease (AD), due to reduction i
Isolation of endophytic fungi and screening of Huperzine A-producing fungus from Huperzia serrata in Vietnam.
Thi Minh Le T, Thi Hong Hoang A, Thi Bich Le T, Thi Bich Vo T, Van Quyen D, Hoang Chu H. Thi Minh Le T, et al. Sci Rep. 2019 Nov 6;9(1):16152. doi: 10.1038/s41598-019-52481-2. Sci Rep. 2019. PMID: 31695105 Free PMC article.
Huperzine A (HupA), a natural Lycopodium alkaloid derived from Huperzia serrata (Thunb. ex Murray) Trev. plants, is a highly active acetylcholinesterase inhibitor and a key compound used for treating Alzheimer's disease (AD). ...The other strains remained uni …
Huperzine A (HupA), a natural Lycopodium alkaloid derived from Huperzia serrata (Thunb. ex Murray) Trev. plants, is a highly active acety
Simple chalcones and bis-chalcones ethers as possible pleiotropic agents.
Liargkova T, Hadjipavlou-Litina DJ, Koukoulitsa C, Voulgari E, Avgoustakis C. Liargkova T, et al. J Enzyme Inhib Med Chem. 2016;31(2):302-13. doi: 10.3109/14756366.2015.1021253. Epub 2015 Mar 23. J Enzyme Inhib Med Chem. 2016. PMID: 25798685 Free article.
Their lipophilicity is experimentally determined by reversed-phase thin-layer chromatography method. Most of them are potent in vitro inhibitors of lipid peroxidation and of LOX. ...The results led us to propose these enone derivatives as new multifunctional …
Their lipophilicity is experimentally determined by reversed-phase thin-layer chromatography method. Most of them are p …
N-Methyl Costaricine and Costaricine, Two Potent Butyrylcholinesterase Inhibitors from Alseodaphne pendulifolia Gamb.
Husna Hasnan MH, Sivasothy Y, Khaw KY, Nafiah MA, Hazni H, Litaudon M, Wan Ruzali WA, Liew SY, Awang K. Husna Hasnan MH, et al. Int J Mol Sci. 2023 Jun 27;24(13):10699. doi: 10.3390/ijms241310699. Int J Mol Sci. 2023. PMID: 37445877 Free PMC article.
Studies have been conducted over the last decade to identify secondary metabolites from plants, in particular those from the class of alkaloids, for the development of new anti-Alzheimer's disease (AD) drugs. The genus Alseodaphne, comprising a wide range of alkaloi …
Studies have been conducted over the last decade to identify secondary metabolites from plants, in particular those from the class of alkalo …
Tacrine and its analogues impair mitochondrial function and bioenergetics: a lipidomic analysis in rat brain.
Melo T, Videira RA, André S, Maciel E, Francisco CS, Oliveira-Campos AM, Rodrigues LM, Domingues MR, Peixoto F, Manuel Oliveira M. Melo T, et al. J Neurochem. 2012 Mar;120(6):998-1013. doi: 10.1111/j.1471-4159.2011.07636.x. Epub 2012 Feb 10. J Neurochem. 2012. PMID: 22192081 Free article.
Tacrine is an acetylcholinesterase (AChE) inhibitor used as a cognitive enhancer in the treatment of Alzheimer's disease (AD). ...
Tacrine is an acetylcholinesterase (AChE) inhibitor used as a cognitive enhancer in the treatment of Alzheimer's disease
64 results