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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2003 1
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31 results

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Page 1
Acid-sensing ion channels (ASICs): pharmacology and implication in pain.
Deval E, Gasull X, Noël J, Salinas M, Baron A, Diochot S, Lingueglia E. Deval E, et al. Pharmacol Ther. 2010 Dec;128(3):549-58. doi: 10.1016/j.pharmthera.2010.08.006. Epub 2010 Aug 31. Pharmacol Ther. 2010. PMID: 20807551 Review.
Protons are indeed among the first factors released by injured tissues, inducing a local pH fall that depolarizes peripheral free terminals of nociceptors and leads to pain. ASICs are excitatory cation channels directly gated by extracellular protons that are …
Protons are indeed among the first factors released by injured tissues, inducing a local pH fall that depolarizes peripheral free terminals …
Acid-sensing ion channels in gastrointestinal function.
Holzer P. Holzer P. Neuropharmacology. 2015 Jul;94:72-9. doi: 10.1016/j.neuropharm.2014.12.009. Epub 2015 Jan 9. Neuropharmacology. 2015. PMID: 25582294 Free PMC article. Review.
The pH in the oesophagus, stomach and intestine is surveyed by a network of acid sensors among which acid-sensing ion channels (ASICs) and acid-sensitive members of transient receptor potential ion channels take a spe …
The pH in the oesophagus, stomach and intestine is surveyed by a network of acid sensors among which acid-sensing io …
Acid-sensing ion channels: A new target for pain and CNS diseases.
Sluka KA, Winter OC, Wemmie JA. Sluka KA, et al. Curr Opin Drug Discov Devel. 2009 Sep;12(5):693-704. Curr Opin Drug Discov Devel. 2009. PMID: 19736627 Free PMC article. Review.
One emerging class of pH-detecting receptors is that of the acid-sensing ion channels (ASICs). Advances in ASIC research have improved the understanding of the role played by pH dynamics in physiological and pathophysiological processes. ...Howe …
One emerging class of pH-detecting receptors is that of the acid-sensing ion channels (ASICs). Advances i …
Acid-sensitive ion channels and receptors.
Holzer P. Holzer P. Handb Exp Pharmacol. 2009;(194):283-332. doi: 10.1007/978-3-540-79090-7_9. Handb Exp Pharmacol. 2009. PMID: 19655111 Free PMC article. Review.
Protons evoke multiple currents in primary afferent neurons, which are carried by several acid-sensitive ion channels. Among these, acid-sensing ion channels (ASICs) and transient receptor potential (TRP) vanilloid-1 (TRPV1) …
Protons evoke multiple currents in primary afferent neurons, which are carried by several acid-sensitive ion channels. …
ASICs as therapeutic targets for migraine.
Dussor G. Dussor G. Neuropharmacology. 2015 Jul;94:64-71. doi: 10.1016/j.neuropharm.2014.12.015. Epub 2015 Jan 9. Neuropharmacology. 2015. PMID: 25582295 Free PMC article. Review.
Decreased extracellular pH and subsequent activation of acid-sensing ion channels (ASICs) may contribute to each of these processes and may thus play a role in migraine pathophysiology. ...This article is part of the Special Issue entitled 'A …
Decreased extracellular pH and subsequent activation of acid-sensing ion channels (ASICs) may contribute …
Peptides inhibitors of acid-sensing ion channels.
Diochot S, Salinas M, Baron A, Escoubas P, Lazdunski M. Diochot S, et al. Toxicon. 2007 Feb;49(2):271-84. doi: 10.1016/j.toxicon.2006.09.026. Epub 2006 Oct 4. Toxicon. 2007. PMID: 17113616 Review.
Acid-sensing ion channels (ASICs) channels are proton-gated cationic channels mainly expressed in central and peripheric nervous system and related to the epithelial amiloride-sensitive Na(+) channels and to the degenerin fa …
Acid-sensing ion channels (ASICs) channels are proton-gated cationic channels mainly expres …
CCK-8 enhances acid-sensing ion channel currents in rat primary sensory neurons.
Qin QR, Xu ZQ, Liu TT, Li XM, Qiu CY, Hu WP. Qin QR, et al. Neuropharmacology. 2023 Dec 15;241:109739. doi: 10.1016/j.neuropharm.2023.109739. Epub 2023 Oct 10. Neuropharmacology. 2023. PMID: 37820935
Cholecystokinin (CCK) is a peptide that has been implicated in pain modulation. Acid sensitive ion channels (ASICs) also play an important role in pain associated with tissue acidification. ...Pretreatment with CCK-8 concentration- …
Cholecystokinin (CCK) is a peptide that has been implicated in pain modulation. Acid sensitive ion channels …
Modulation of acid-sensing ion channels by hydrogen sulfide.
Mukhopadhyay M, Bera AK. Mukhopadhyay M, et al. Biochem Biophys Res Commun. 2020 Jun 18;527(1):71-75. doi: 10.1016/j.bbrc.2020.04.092. Epub 2020 Apr 25. Biochem Biophys Res Commun. 2020. PMID: 32446393
Acid-sensing ion channels (ASICs) have been implicated in many physiological and patho-physiological processes like synaptic plasticity, inflammation, pain perception, stroke-induced brain damage and, drug-seeking behaviour. ...The …
Acid-sensing ion channels (ASICs) have been implicated in many physiological and patho-physiologic …
Acid-sensing ion channels regulate spontaneous inhibitory activity in the hippocampus: possible implications for epilepsy.
Ievglevskyi O, Isaev D, Netsyk O, Romanov A, Fedoriuk M, Maximyuk O, Isaeva E, Akaike N, Krishtal O. Ievglevskyi O, et al. Philos Trans R Soc Lond B Biol Sci. 2016 Aug 5;371(1700):20150431. doi: 10.1098/rstb.2015.0431. Philos Trans R Soc Lond B Biol Sci. 2016. PMID: 27377725 Free PMC article.
Acid-sensing ion channels (ASICs) play an important role in numerous functions in the central and peripheral nervous systems ranging from memory and emotions to pain. ...Inhibition of ASICs leads to a strong increase in the frequen …
Acid-sensing ion channels (ASICs) play an important role in numerous functions in the central and periphe …
Toxin peptides targeting acid-sensing ion channels: Opportunities for cancer diagnosis and therapy.
Baudat R, Diochot S, Lange L, Lingueglia E, Benoit E, Servent D. Baudat R, et al. Biomed Pharmacother. 2026 Mar;196:119129. doi: 10.1016/j.biopha.2026.119129. Epub 2026 Feb 18. Biomed Pharmacother. 2026. PMID: 41713031 Free article. Review.
Acid-sensing ion channels (ASICs) are proton-gated cation channels widely expressed throughout the mammalian nervous system, where they play key roles in processes such as neuronal excitability, synaptic plasticity and pain percept …
Acid-sensing ion channels (ASICs) are proton-gated cation channels widely expressed throughout the …
31 results