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112 results
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Engineering broadly neutralizing antibodies for HIV prevention and therapy.
Hua CK, Ackerman ME. Hua CK, et al. Among authors: ackerman me. Adv Drug Deliv Rev. 2016 Aug 1;103:157-173. doi: 10.1016/j.addr.2016.01.013. Epub 2016 Jan 29. Adv Drug Deliv Rev. 2016. PMID: 26827912 Free PMC article. Review.
Emerging concepts on the role of innate immunity in the prevention and control of HIV infection.
Ackerman ME, Dugast AS, Alter G. Ackerman ME, et al. Annu Rev Med. 2012;63:113-30. doi: 10.1146/annurev-med-050310-085221. Epub 2011 Nov 8. Annu Rev Med. 2012. PMID: 22077718 Review.
High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples.
Brown EP, Licht AF, Dugast AS, Choi I, Bailey-Kellogg C, Alter G, Ackerman ME. Brown EP, et al. Among authors: ackerman me. J Immunol Methods. 2012 Dec 14;386(1-2):117-23. doi: 10.1016/j.jim.2012.09.007. Epub 2012 Sep 27. J Immunol Methods. 2012. PMID: 23023091 Free PMC article.
Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b.
Ackerman ME, Dugast AS, McAndrew EG, Tsoukas S, Licht AF, Irvine DJ, Alter G. Ackerman ME, et al. J Virol. 2013 May;87(10):5468-76. doi: 10.1128/JVI.03403-12. Epub 2013 Mar 6. J Virol. 2013. PMID: 23468489 Free PMC article.
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity.
Ackerman ME, Crispin M, Yu X, Baruah K, Boesch AW, Harvey DJ, Dugast AS, Heizen EL, Ercan A, Choi I, Streeck H, Nigrovic PA, Bailey-Kellogg C, Scanlan C, Alter G. Ackerman ME, et al. J Clin Invest. 2013 May;123(5):2183-92. doi: 10.1172/JCI65708. Epub 2013 Apr 8. J Clin Invest. 2013. PMID: 23563315 Free PMC article.
Mapping the journey to an HIV vaccine.
Ackerman M, Alter G. Ackerman M, et al. N Engl J Med. 2013 Jul 25;369(4):389-91. doi: 10.1056/NEJMcibr1304437. N Engl J Med. 2013. PMID: 23883384 No abstract available.
Opportunities to exploit non-neutralizing HIV-specific antibody activity.
Ackerman ME, Alter G. Ackerman ME, et al. Curr HIV Res. 2013 Jul;11(5):365-77. doi: 10.2174/1570162x113116660058. Curr HIV Res. 2013. PMID: 24191934 Free PMC article. Review.
Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers.
Lai JI, Licht AF, Dugast AS, Suscovich T, Choi I, Bailey-Kellogg C, Alter G, Ackerman ME. Lai JI, et al. Among authors: ackerman me. J Virol. 2014 Mar;88(5):2799-809. doi: 10.1128/JVI.03130-13. Epub 2013 Dec 18. J Virol. 2014. PMID: 24352471 Free PMC article.
An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.
Bonsignori M, Wiehe K, Grimm SK, Lynch R, Yang G, Kozink DM, Perrin F, Cooper AJ, Hwang KK, Chen X, Liu M, McKee K, Parks RJ, Eudailey J, Wang M, Clowse M, Criscione-Schreiber LG, Moody MA, Ackerman ME, Boyd SD, Gao F, Kelsoe G, Verkoczy L, Tomaras GD, Liao HX, Kepler TB, Montefiori DC, Mascola JR, Haynes BF. Bonsignori M, et al. Among authors: ackerman me. J Clin Invest. 2014 Apr;124(4):1835-43. doi: 10.1172/JCI73441. Epub 2014 Mar 10. J Clin Invest. 2014. PMID: 24614107 Free PMC article.
Lack of protection following passive transfer of polyclonal highly functional low-dose non-neutralizing antibodies.
Dugast AS, Chan Y, Hoffner M, Licht A, Nkolola J, Li H, Streeck H, Suscovich TJ, Ghebremichael M, Ackerman ME, Barouch DH, Alter G. Dugast AS, et al. Among authors: ackerman me. PLoS One. 2014 May 12;9(5):e97229. doi: 10.1371/journal.pone.0097229. eCollection 2014. PLoS One. 2014. PMID: 24820481 Free PMC article.
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