New flavonol glycosides from Aconitum burnatii Gáyer and Aconitum variegatum L

Fitoterapia. 2010 Oct;81(7):940-7. doi: 10.1016/j.fitote.2010.06.012. Epub 2010 Jun 20.

Abstract

Six flavonol glycosides, compounds 1-3 from A. burnatii Gáyer and 4-6 from A. variegatum L., were obtained from their methanol extracts of aerial parts. The identified structures were quercetin 3-O-β-D-glucopyranoside-7-O-(6-E-p-coumaroyl)-β-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranoside (1), quercetin 3-O-β-D-glucopyranoside-7-O-β-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranoside (2), quercetin 3-O-β-D-glucopyranoside-7-O-(6-E-caffeoyl)-β-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranoside (3), kaempferol 3-O-β-D-galactopyranoside-7-O-α-L-arabinopyranoside (4), quercetin 3-O-β-D-glucopyranoside (5), and kaempferol 3-O-β-D-glucopyranoside (6). Compounds 1, 2 and 4 were isolated for the first time. The antioxidant potential of the methanol extracts and pure compounds was tested with different assays.

MeSH terms

  • Aconitum / chemistry*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Flavonols / chemistry
  • Flavonols / isolation & purification*
  • Flavonols / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Molecular Structure
  • Plant Components, Aerial
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology

Substances

  • Antioxidants
  • Flavonols
  • Glycosides
  • Plant Extracts