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NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes.
Singh A, Daemen A, Nickles D, Jeon SM, Foreman O, Sudini K, Gnad F, Lajoie S, Gour N, Mitzner W, Chatterjee S, Choi EJ, Ravishankar B, Rappaport A, Patil N, McCleland M, Johnson L, Acquaah-Mensah G, Gabrielson E, Biswal S, Hatzivassiliou G. Singh A, et al. Among authors: acquaah mensah g. Clin Cancer Res. 2021 Feb 1;27(3):877-888. doi: 10.1158/1078-0432.CCR-20-1985. Epub 2020 Oct 19. Clin Cancer Res. 2021. PMID: 33077574 Free PMC article.
Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis.
Singh A, Happel C, Manna SK, Acquaah-Mensah G, Carrerero J, Kumar S, Nasipuri P, Krausz KW, Wakabayashi N, Dewi R, Boros LG, Gonzalez FJ, Gabrielson E, Wong KK, Girnun G, Biswal S. Singh A, et al. J Clin Invest. 2013 Jul;123(7):2921-34. doi: 10.1172/JCI66353. Epub 2013 Jun 10. J Clin Invest. 2013. PMID: 23921124 Free PMC article.
De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer.
Singh A, Ruiz C, Bhalla K, Haley JA, Li QK, Acquaah-Mensah G, Montal E, Sudini KR, Skoulidis F, Wistuba II, Papadimitrakopoulou V, Heymach JV, Boros LG, Gabrielson E, Carretero J, Wong KK, Haley JD, Biswal S, Girnun GD. Singh A, et al. Among authors: acquaah mensah g. FASEB J. 2018 Jun 15;32(12):fj201800204. doi: 10.1096/fj.201800204. Online ahead of print. FASEB J. 2018. PMID: 29906244 Free PMC article.
29 results