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Genetic pathways in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia.
Pedersen-Bjergaard J, Andersen MT, Andersen MK. Pedersen-Bjergaard J, et al. Hematology Am Soc Hematol Educ Program. 2007:392-7. doi: 10.1182/asheducation-2007.1.392. Hematology Am Soc Hematol Educ Program. 2007. PMID: 18024656 Review.
In therapy-related myelodysplasia (t-MDS) and acute myeloid leukemia (t-AML), at least eight alternative genetic pathways have been defined based on characteristic recurrent chromosome abnormalities. Patients presenting as t-MDS and patients presenting …
In therapy-related myelodysplasia (t-MDS) and acute myeloid leukemia (t-AML), at least eight alternative genetic …
[Therapy-induced leukemia -- an underestimated complication of antineoplastic chemotherapy?].
Dührsen U. Dührsen U. Zentralbl Gynakol. 2005 Aug;127(4):235-41. doi: 10.1055/s-2005-836562. Zentralbl Gynakol. 2005. PMID: 16037905 Review. German.
Alkylating agents and topoisomerase II inhibitors are mutagenic cytotoxic drugs which may induce therapy-related acute myeloid leukemia or myelodysplasia. The frequency of these complications depends on the type of agent used, its …
Alkylating agents and topoisomerase II inhibitors are mutagenic cytotoxic drugs which may induce therapy-related acu …