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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1976 1
1978 1
1979 2
1980 1
1981 1
1982 1
1983 1
1984 3
1985 1
1986 1
1987 6
1988 8
1989 5
1990 10
1991 18
1992 31
1993 44
1994 52
1995 32
1996 48
1997 31
1998 32
1999 50
2000 49
2001 72
2002 73
2003 61
2004 52
2005 33
2006 42
2007 63
2008 40
2009 35
2010 39
2011 48
2012 46
2013 42
2014 65
2015 41
2016 33
2017 26
2018 33
2019 36
2020 40
2021 34
2022 27
2023 13

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1,352 results

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Page 1
Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet.
Sanz MA, Fenaux P, Tallman MS, Estey EH, Löwenberg B, Naoe T, Lengfelder E, Döhner H, Burnett AK, Chen SJ, Mathews V, Iland H, Rego E, Kantarjian H, Adès L, Avvisati G, Montesinos P, Platzbecker U, Ravandi F, Russell NH, Lo-Coco F. Sanz MA, et al. Blood. 2019 Apr 11;133(15):1630-1643. doi: 10.1182/blood-2019-01-894980. Epub 2019 Feb 25. Blood. 2019. PMID: 30803991 Free PMC article. Review.
Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 2009, several studies have provided important insights, particularly regarding the role of arsenic trioxide (ATO) in frontline therapy. ...
Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 2009, seve …
Acute promyelocytic leukemia current treatment algorithms.
Yilmaz M, Kantarjian H, Ravandi F. Yilmaz M, et al. Blood Cancer J. 2021 Jun 30;11(6):123. doi: 10.1038/s41408-021-00514-3. Blood Cancer J. 2021. PMID: 34193815 Free PMC article. Review.
In 1957, Hillestad et al. defined acute promyelocytic leukemia (APL) for the first time in the literature as a distinct type of acute myeloid leukemia (AML) with a "rapid downhill course" characterized with a severe bleeding tendency. APL, accou …
In 1957, Hillestad et al. defined acute promyelocytic leukemia (APL) for the first time in the literature as a distinct …
Differentiation syndrome in acute promyelocytic leukaemia.
Stahl M, Tallman MS. Stahl M, et al. Br J Haematol. 2019 Oct;187(2):157-162. doi: 10.1111/bjh.16151. Epub 2019 Aug 13. Br J Haematol. 2019. PMID: 31410848 Free article. Review.
Acute promyelocytic leukaemia differentiation syndrome (APL DS) is seen when patients with APL are treated with all-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO). Presenting symptoms are varied but frequently include dyspnoea, unexplained fever, we …
Acute promyelocytic leukaemia differentiation syndrome (APL DS) is seen when patients with APL are treated with all-tra …
Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants.
Mannan A, Muhsen IN, Barragán E, Sanz MA, Mohty M, Hashmi SK, Aljurf M. Mannan A, et al. Hematol Oncol Stem Cell Ther. 2020 Dec;13(4):189-201. doi: 10.1016/j.hemonc.2020.05.007. Epub 2020 May 20. Hematol Oncol Stem Cell Ther. 2020. PMID: 32473106 Free article. Review.
Acute promyelocytic leukemia (APL) is a special disease entity of acute myeloid leukemia (AML). ...
Acute promyelocytic leukemia (APL) is a special disease entity of acute myeloid leukemia (AML). ...
RARA fusion genes in acute promyelocytic leukemia: a review.
De Braekeleer E, Douet-Guilbert N, De Braekeleer M. De Braekeleer E, et al. Expert Rev Hematol. 2014 Jun;7(3):347-57. doi: 10.1586/17474086.2014.903794. Epub 2014 Apr 10. Expert Rev Hematol. 2014. PMID: 24720386 Review.
The t(15;17)(q24;q21), generating a PML-RARA fusion gene, is the hallmark of acute promyelocytic leukemia (APL). At present, eight other genes fusing with RARA have been identified. ...
The t(15;17)(q24;q21), generating a PML-RARA fusion gene, is the hallmark of acute promyelocytic leukemia (APL). At pre …
Acute promyelocytic leukemia: from highly fatal to highly curable.
Wang ZY, Chen Z. Wang ZY, et al. Blood. 2008 Mar 1;111(5):2505-15. doi: 10.1182/blood-2007-07-102798. Blood. 2008. PMID: 18299451 Free article. Review.
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia. Morphologically, it is identified as the M3 subtype of acute myeloid leukemia by the French-American-British classification and cytogenetically is …
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia. Morphologically, it i …
Morphological and Immunophenotypic Clues to the WHO Categories of Acute Myeloid Leukaemia.
Bain BJ, Béné MC. Bain BJ, et al. Acta Haematol. 2019;141(4):232-244. doi: 10.1159/000496097. Epub 2019 Apr 9. Acta Haematol. 2019. PMID: 30965338 Free article. Review.
Diagnosis and classification of acute myeloid leukaemia (AML) require cytogenetic and molecular genetic investigation. However, while these evaluations are pending, morphology supplemented by immunophenotyping can provide clues to the diagnosis of specific cytogenet …
Diagnosis and classification of acute myeloid leukaemia (AML) require cytogenetic and molecular genetic investigation. However …
Clinical implications of molecular markers in acute myeloid leukemia.
Kayser S, Levis MJ. Kayser S, et al. Eur J Haematol. 2019 Jan;102(1):20-35. doi: 10.1111/ejh.13172. Epub 2018 Oct 23. Eur J Haematol. 2019. PMID: 30203623 Free PMC article. Review.
The recently updated World Health Organization (WHO) Classification of myeloid neoplasms and leukemia reflects the fact that research in the underlying pathogenic mechanisms of acute myeloid leukemia (AML) has led to remarkable advances in our understanding o …
The recently updated World Health Organization (WHO) Classification of myeloid neoplasms and leukemia reflects the fact that research …
Overview of all-trans-retinoic acid (ATRA) and its analogues: Structures, activities, and mechanisms in acute promyelocytic leukaemia.
Liang C, Qiao G, Liu Y, Tian L, Hui N, Li J, Ma Y, Li H, Zhao Q, Cao W, Liu H, Ren X. Liang C, et al. Eur J Med Chem. 2021 Aug 5;220:113451. doi: 10.1016/j.ejmech.2021.113451. Epub 2021 Apr 15. Eur J Med Chem. 2021. PMID: 33895500 Review.
All-trans-retinoic acid (ATRA) is effective for preventing cancer and treating skin diseases and acute promyelocytic leukaemia (APL). These pharmacological effects of ATRA are mainly mediated by retinoid X receptors (RXRs) and retinoic acid receptors (RARs). …
All-trans-retinoic acid (ATRA) is effective for preventing cancer and treating skin diseases and acute promyelocytic leukae …
Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet.
Sanz MA, Grimwade D, Tallman MS, Lowenberg B, Fenaux P, Estey EH, Naoe T, Lengfelder E, Büchner T, Döhner H, Burnett AK, Lo-Coco F. Sanz MA, et al. Blood. 2009 Feb 26;113(9):1875-91. doi: 10.1182/blood-2008-04-150250. Epub 2008 Sep 23. Blood. 2009. PMID: 18812465 Free article. Review.
The introduction of all-trans retinoic acid (ATRA) and, more recently, arsenic trioxide (ATO) into the therapy of acute promyelocytic leukemia (APL) has revolutionized the management and outcome of this disease. ...
The introduction of all-trans retinoic acid (ATRA) and, more recently, arsenic trioxide (ATO) into the therapy of acute promyelocy …
1,352 results