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Acute lung injury in children: therapeutic practice and feasibility of international clinical trials.
Santschi M, Jouvet P, Leclerc F, Gauvin F, Newth CJ, Carroll CL, Flori H, Tasker RC, Rimensberger PC, Randolph AG; PALIVE Investigators; Pediatric Acute Lung Injury and Sepsis Investigators Network (PALISI); European Society of Pediatric and Neonatal Intensive Care (ESPNIC). Santschi M, et al. Pediatr Crit Care Med. 2010 Nov;11(6):681-9. doi: 10.1097/PCC.0b013e3181d904c0. Pediatr Crit Care Med. 2010. PMID: 20228688
In contrast to adult medicine, there are few clinical trials to guide mechanical ventilation management in children with acute lung injury. ...CONCLUSIONS: Our study reveals inconsistent mechanical ventilation practice and use of a …
In contrast to adult medicine, there are few clinical trials to guide mechanical ventilation management in children wit …
Evidence-Based and Clinically Relevant Outcomes for Hemorrhage Control Trauma Trials.
Holcomb JB, Moore EE, Sperry JL, Jansen JO, Schreiber MA, Del Junco DJ, Spinella PC, Sauaia A, Brohi K, Bulger EM, Cap AP, Hess JR, Jenkins D, Lewis RJ, Neal MD, Newgard C, Pati S, Pusateri AE, Rizoli S, Russell RT, Shackelford SA, Stein DM, Steiner ME, Wang H, Ward KR, Young P. Holcomb JB, et al. Ann Surg. 2021 Mar 1;273(3):395-401. doi: 10.1097/SLA.0000000000004563. Ann Surg. 2021. PMID: 33065652
OBJECTIVE: To address the clinical and regulatory challenges of optimal primary endpoints for bleeding patients by developing consensus-based recommendations for primary clinical outcomes for pivotal trials in patients within 6 categories of significant bleed …
OBJECTIVE: To address the clinical and regulatory challenges of optimal primary endpoints for bleeding patients by developing consens …