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Acute physiologic and chronic histologic changes in rats and mice exposed to the unique hallucinogen salvinorin A.
Mowry M, Mosher M, Briner W. Mowry M, et al. J Psychoactive Drugs. 2003 Jul-Sep;35(3):379-82. doi: 10.1080/02791072.2003.10400021. J Psychoactive Drugs. 2003. PMID: 14621136
Little data is available on the medical effects of this substance so animal studies were undertaken to explore the acute toxic effects of this substance in rats and the chronic effects in mice. ...No effects were seen on cardiac conduction, temperature …
Little data is available on the medical effects of this substance so animal studies were undertaken to explore the acute toxic effect …
A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control.
Widenmaier SB, Kim SJ, Yang GK, De Los Reyes T, Nian C, Asadi A, Seino Y, Kieffer TJ, Kwok YN, McIntosh CH. Widenmaier SB, et al. PLoS One. 2010 Mar 9;5(3):e9590. doi: 10.1371/journal.pone.0009590. PLoS One. 2010. PMID: 20231880 Free PMC article.
MATERIALS AND METHODS: The insulinotropic and pro-survival potency of D-GIP(1-30) was evaluated in perfused pancreas preparations and cultured INS-1 beta-cells, respectively, and receptor selectivity evaluated using wild type and GIP receptor knockout mice. Effects of D-GI …
MATERIALS AND METHODS: The insulinotropic and pro-survival potency of D-GIP(1-30) was evaluated in perfused pancreas preparations and cultur …