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A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters.
Bricker TL, Darling TL, Hassan AO, Harastani HH, Soung A, Jiang X, Dai YN, Zhao H, Adams LJ, Holtzman MJ, Bailey AL, Case JB, Fremont DH, Klein R, Diamond MS, Boon ACM. Bricker TL, et al. Among authors: adams lj. Cell Rep. 2021 Jul 20;36(3):109400. doi: 10.1016/j.celrep.2021.109400. Epub 2021 Jun 29. Cell Rep. 2021. PMID: 34245672 Free PMC article.
Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice.
Case JB, Rothlauf PW, Chen RE, Kafai NM, Fox JM, Smith BK, Shrihari S, McCune BT, Harvey IB, Keeler SP, Bloyet LM, Zhao H, Ma M, Adams LJ, Winkler ES, Holtzman MJ, Fremont DH, Whelan SPJ, Diamond MS. Case JB, et al. Among authors: adams lj. Cell Host Microbe. 2020 Sep 9;28(3):465-474.e4. doi: 10.1016/j.chom.2020.07.018. Epub 2020 Jul 30. Cell Host Microbe. 2020. PMID: 32798445 Free PMC article.
A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.
Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, Dai YN, Ma M, Adams LJ, Shrihari S, Danis JE, Gralinski LE, Hou YJ, Schäfer A, Kim AS, Keeler SP, Weiskopf D, Baric RS, Holtzman MJ, Fremont DH, Curiel DT, Diamond MS. Hassan AO, et al. Among authors: adams lj. Cell. 2020 Oct 1;183(1):169-184.e13. doi: 10.1016/j.cell.2020.08.026. Epub 2020 Aug 19. Cell. 2020. PMID: 32931734 Free PMC article.
A single intranasal or intramuscular immunization with chimpanzee adenovirus vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters.
Bricker TL, Darling TL, Hassan AO, Harastani HH, Soung A, Jiang X, Dai YN, Zhao H, Adams LJ, Holtzman MJ, Bailey AL, Case JB, Fremont DH, Klein R, Diamond MS, Boon ACM. Bricker TL, et al. Among authors: adams lj. bioRxiv [Preprint]. 2020 Dec 3:2020.12.02.408823. doi: 10.1101/2020.12.02.408823. bioRxiv. 2020. PMID: 33299991 Free PMC article. Updated. Preprint.
A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope.
VanBlargan L, Adams L, Liu Z, Chen RE, Gilchuk P, Raju S, Smith B, Zhao H, Case JB, Winkler ES, Whitener B, Droit L, Aziati I, Shi PY, Creanga A, Pegu A, Handley S, Wang D, Boon A, Crowe JE, Whelan SPJ, Fremont D, Diamond M. VanBlargan L, et al. bioRxiv [Preprint]. 2021 Apr 26:2021.04.26.441501. doi: 10.1101/2021.04.26.441501. bioRxiv. 2021. PMID: 33907753 Free PMC article. Updated. Preprint.
An intranasal vaccine durably protects against SARS-CoV-2 variants in mice.
Hassan AO, Shrihari S, Gorman MJ, Ying B, Yuan D, Raju S, Chen RE, Dmitriev IP, Kashentseva E, Adams LJ, Mann C, Davis-Gardner ME, Suthar MS, Shi PY, Saphire EO, Fremont DH, Curiel DT, Alter G, Diamond MS. Hassan AO, et al. Among authors: adams lj. Cell Rep. 2021 Jul 27;36(4):109452. doi: 10.1016/j.celrep.2021.109452. Epub 2021 Jul 10. Cell Rep. 2021. PMID: 34289385 Free PMC article.
A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
VanBlargan LA, Adams LJ, Liu Z, Chen RE, Gilchuk P, Raju S, Smith BK, Zhao H, Case JB, Winkler ES, Whitener BM, Droit L, Aziati ID, Bricker TL, Joshi A, Shi PY, Creanga A, Pegu A, Handley SA, Wang D, Boon ACM, Crowe JE Jr, Whelan SPJ, Fremont DH, Diamond MS. VanBlargan LA, et al. Among authors: adams lj. Immunity. 2021 Oct 12;54(10):2399-2416.e6. doi: 10.1016/j.immuni.2021.08.016. Epub 2021 Aug 19. Immunity. 2021. PMID: 34481543 Free PMC article.
mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes.
Zimmerman O, Altman Doss AM, Kaplonek P, Liang CY, VanBlargan LA, Chen RE, Monroy JM, Wedner HJ, Kulczycki A Jr, Mantia TL, O'Shaughnessy CC, Davis-Adams HG, Bertera HL, Adams LJ, Raju S, Zhao FR, Rigell CJ, Dy TB, Kau AL, Ren Z, Turner JS, O'Halloran JA, Presti RM, Fremont DH, Kendall PL, Ellebedy AH, Alter G, Diamond MS. Zimmerman O, et al. Among authors: adams lj. Cell Rep Med. 2022 Jun 21;3(6):100653. doi: 10.1016/j.xcrm.2022.100653. Epub 2022 Jun 9. Cell Rep Med. 2022. PMID: 35688161 Free PMC article.
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