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Page 1
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Teng Y, Xu F, Zhang X, Mu J, Sayed M, Hu X, Lei C, Sriwastva M, Kumar A, Sundaram K, Zhang L, Park JW, Chen SY, Zhang S, Yan J, Merchant ML, Zhang X, McClain CJ, Wolfe JK, Adcock RS, Chung D, Palmer KE, Zhang HG. Teng Y, et al. Among authors: adcock rs. Mol Ther. 2021 Aug 4;29(8):2424-2440. doi: 10.1016/j.ymthe.2021.05.005. Epub 2021 May 11. Mol Ther. 2021. PMID: 33984520 Free PMC article.
Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.
Chung DH, Golden JE, Adcock RS, Schroeder CE, Chu YK, Sotsky JB, Cramer DE, Chilton PM, Song C, Anantpadma M, Davey RA, Prodhan AI, Yin X, Zhang X. Chung DH, et al. Among authors: adcock rs. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4552-62. doi: 10.1128/AAC.00282-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27185801 Free PMC article.
Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids.
Diamond G, Molchanova N, Herlan C, Fortkort JA, Lin JS, Figgins E, Bopp N, Ryan LK, Chung D, Adcock RS, Sherman M, Barron AE. Diamond G, et al. Among authors: adcock rs. Pharmaceuticals (Basel). 2021 Mar 31;14(4):304. doi: 10.3390/ph14040304. Pharmaceuticals (Basel). 2021. PMID: 33807248 Free PMC article.
Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients.
Rouchka EC, Chariker JH, Alejandro B, Adcock RS, Singhal R, Ramirez J, Palmer KE, Lasnik AB, Carrico R, Arnold FW, Furmanek S, Zhang M, Wolf LA, Waigel S, Zacharias W, Bordon J, Chung D. Rouchka EC, et al. Among authors: adcock rs. Sci Rep. 2021 Aug 3;11(1):15715. doi: 10.1038/s41598-021-95197-y. Sci Rep. 2021. PMID: 34344959 Free PMC article.
Identification of potent small molecule inhibitors of SARS-CoV-2 entry.
Mediouni S, Mou H, Otsuka Y, Jablonski JA, Adcock RS, Batra L, Chung DH, Rood C, de Vera IMS, Rahaim R Jr, Ullah S, Yu X, Getmanenko YA, Kennedy NM, Wang C, Nguyen TT, Hull M, Chen E, Bannister TD, Baillargeon P, Scampavia L, Farzan M, Valente ST, Spicer TP. Mediouni S, et al. Among authors: adcock rs. SLAS Discov. 2022 Jan;27(1):8-19. doi: 10.1016/j.slasd.2021.10.012. Epub 2021 Oct 23. SLAS Discov. 2022. PMID: 35058179 Free PMC article.
Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models.
Cao X, Yang D, Parvathareddy J, Chu YK, Kim EJ, Fitz-Henley JN, Li X, Lukka PB, Parmar KR, Temrikar ZH, Dhole P, Adcock RS, Gabbard J, Bansal S, Lee J, Zalduondo L, Hayes E, Stabenow J, Meibohm B, Fitzpatrick EA, Bailey K, Campos RK, Julander JG, Rossi SL, Chung D, Jonsson CB, Golden JE. Cao X, et al. Among authors: adcock rs. Sci Transl Med. 2023 Apr 12;15(691):eabl9344. doi: 10.1126/scitranslmed.abl9344. Epub 2023 Apr 12. Sci Transl Med. 2023. PMID: 37043558
12 results