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Page 1
Activation of parkin by a molecular glue.
Sauvé V, Stefan E, Croteau N, Goiran T, Fakih R, Bansal N, Hadzipasic A, Fang J, Murugan P, Chen S, Fon EA, Hirst WD, Silvian LF, Trempe JF, Gehring K. Sauvé V, et al. Among authors: hadzipasic a. Nat Commun. 2024 Sep 19;15(1):7707. doi: 10.1038/s41467-024-51889-3. Nat Commun. 2024. PMID: 39300082 Free PMC article.
A biophysical framework for double-drugging kinases.
Kim C, Ludewig H, Hadzipasic A, Kutter S, Nguyen V, Kern D. Kim C, et al. Among authors: hadzipasic a. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2304611120. doi: 10.1073/pnas.2304611120. Epub 2023 Aug 17. Proc Natl Acad Sci U S A. 2023. PMID: 37590418 Free PMC article.
Ancient origins of allosteric activation in a Ser-Thr kinase.
Hadzipasic A, Wilson C, Nguyen V, Kern N, Kim C, Pitsawong W, Villali J, Zheng Y, Kern D. Hadzipasic A, et al. Science. 2020 Feb 21;367(6480):912-917. doi: 10.1126/science.aay9959. Science. 2020. PMID: 32079772 Free PMC article.
Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase.
Shlevkov E, Murugan P, Montagna D, Stefan E, Hadzipasic A, Harvey JS, Kumar PR, Entova S, Bansal N, Bickford S, Wong LY, Hirst WD, Weihofen A, Silvian LF. Shlevkov E, et al. Among authors: hadzipasic a. iScience. 2021 Dec 18;25(1):103650. doi: 10.1016/j.isci.2021.103650. eCollection 2022 Jan 21. iScience. 2021. PMID: 35024585 Free PMC article.