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Fructose, insulin resistance, and metabolic dyslipidemia.
Basciano H, Federico L, Adeli K. Basciano H, et al. Nutr Metab (Lond). 2005 Feb 21;2(1):5. doi: 10.1186/1743-7075-2-5. Nutr Metab (Lond). 2005. PMID: 15723702 Free PMC article.
Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model.
Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K. Taghibiglou C, et al. J Biol Chem. 2000 Mar 24;275(12):8416-25. doi: 10.1074/jbc.275.12.8416. J Biol Chem. 2000. PMID: 10722675
Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.
Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K. Taghibiglou C, et al. J Biol Chem. 2002 Jan 4;277(1):793-803. doi: 10.1074/jbc.M106737200. Epub 2001 Oct 11. J Biol Chem. 2002. PMID: 11598116
Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.
Taghibiglou C, Van Iderstine SC, Kulinski A, Rudy D, Adeli K. Taghibiglou C, et al. Biochem Pharmacol. 2002 Feb 1;63(3):349-60. doi: 10.1016/s0006-2952(01)00918-2. Biochem Pharmacol. 2002. PMID: 11853686
Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity.
Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K. Mangaloglu L, et al. Metabolism. 2002 Apr;51(4):409-18. doi: 10.1053/meta.2002.30954. Metabolism. 2002. PMID: 11912545
Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.
Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF. Carpentier A, et al. J Biol Chem. 2002 Aug 9;277(32):28795-802. doi: 10.1074/jbc.M204568200. Epub 2002 Jun 4. J Biol Chem. 2002. PMID: 12048212
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