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Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial.
Pers YM, Rackwitz L, Ferreira R, Pullig O, Delfour C, Barry F, Sensebe L, Casteilla L, Fleury S, Bourin P, Noël D, Canovas F, Cyteval C, Lisignoli G, Schrauth J, Haddad D, Domergue S, Noeth U, Jorgensen C; ADIPOA Consortium. Pers YM, et al. Stem Cells Transl Med. 2016 Jul;5(7):847-56. doi: 10.5966/sctm.2015-0245. Epub 2016 May 23. Stem Cells Transl Med. 2016. PMID: 27217345 Free PMC article. Clinical Trial.
The present study aimed at evaluating the safety of a dose-escalation protocol of intra-articular injected adipose-derived stromal cells (ASCs) in patients with knee OA, as well as clinical efficacy as secondary endpoint. ...SIGNIFICANCE: …
The present study aimed at evaluating the safety of a dose-escalation protocol of intra-articular injected adipose-deri …
Mesenchymal stromal cells conditioned by peripheral blood mononuclear cells exert enhanced immunomodulation capacities and alleviate a model of Myasthenia Gravis.
Bayer AC, Pinzón N, You A, Bergman C, Dragin N, Corneau A, Truffault F, Noël D, Martinaud C, Le Panse R, Berrih-Aknin S, Vilquin JT. Bayer AC, et al. Stem Cell Res Ther. 2025 Aug 8;16(1):437. doi: 10.1186/s13287-025-04534-9. Stem Cell Res Ther. 2025. PMID: 40781689 Free PMC article.
BACKGROUND: Mesenchymal Stromal Cells (MSC) possess innate immunomodulatory properties, which can be significantly enhanced through co-culture with peripheral blood mononuclear cells (PBMC), making them attractive tools for the treatment of autoimmune and inflammato …
BACKGROUND: Mesenchymal Stromal Cells (MSC) possess innate immunomodulatory properties, which can be significantly enhanced th …