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Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
Greber B, Lehrach H, Adjaye J. Greber B, et al. Stem Cells. 2007 Feb;25(2):455-64. doi: 10.1634/stemcells.2006-0476. Epub 2006 Oct 12. Stem Cells. 2007. PMID: 17038665
Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants.
Mlody B, Wruck W, Martins S, Sperling K, Adjaye J. Mlody B, et al. Sci Rep. 2017 Aug 8;7(1):7516. doi: 10.1038/s41598-017-07905-2. Sci Rep. 2017. PMID: 28790359 Free PMC article.
Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells.
Mertes F, Lichtner B, Kuhl H, Blattner M, Otte J, Wruck W, Timmermann B, Lehrach H, Adjaye J. Mertes F, et al. BMC Genomics. 2015 Nov 12;16:925. doi: 10.1186/s12864-015-2025-z. BMC Genomics. 2015. PMID: 26564201 Free PMC article.
Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations.
Prigione A, Hossini AM, Lichtner B, Serin A, Fauler B, Megges M, Lurz R, Lehrach H, Makrantonaki E, Zouboulis CC, Adjaye J. Prigione A, et al. PLoS One. 2011;6(11):e27352. doi: 10.1371/journal.pone.0027352. Epub 2011 Nov 14. PLoS One. 2011. PMID: 22110631 Free PMC article.
Metabolic restructuring and cell fate conversion.
Prigione A, Ruiz-PĂ©rez MV, Bukowiecki R, Adjaye J. Prigione A, et al. Cell Mol Life Sci. 2015 May;72(9):1759-77. doi: 10.1007/s00018-015-1834-1. Epub 2015 Jan 14. Cell Mol Life Sci. 2015. PMID: 25586562 Review.
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