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Data-driven Stochastic Model for Quantifying the Interplay Between Amyloid-beta and Calcium Levels in Alzheimer's Disease.
Shaheen H, Melnik R, Singh S; Alzheimer’s Disease Neuroimaging Initiative. Shaheen H, et al. Stat Anal Data Min. 2024 Apr;17(2):e11679. doi: 10.1002/sam.11679. Epub 2024 Apr 9. Stat Anal Data Min. 2024. PMID: 38646460
To better understand this interaction, we report a novel stochastic model where we analyze the positive feedback loop between Abeta and Ca+2 using ADNI data. A good therapeutic treatment plan for AD requires precise predictions. ...Incorporating the ADNI data in our …
To better understand this interaction, we report a novel stochastic model where we analyze the positive feedback loop between Abeta and Ca+2 …
AI-based tool for early detection of Alzheimer's disease.
Ul Rehman S, Tarek N, Magdy C, Kamel M, Abdelhalim M, Melek A, N Mahmoud L, Sadek I. Ul Rehman S, et al. Heliyon. 2024 Apr 9;10(8):e29375. doi: 10.1016/j.heliyon.2024.e29375. eCollection 2024 Apr 30. Heliyon. 2024. PMID: 38644855 Free PMC article.
The hippocampus, a pivotal early affected region linked to memory, plays a central role in classifying patients into three categories: cognitively normal (CN), representing individuals without cognitive impairment; mild cognitive impairment (MCI), indicative of a subtle decline i …
The hippocampus, a pivotal early affected region linked to memory, plays a central role in classifying patients into three categories: cogni …
Mapping of Alzheimer's disease related data elements and the NIH Common Data Elements.
Hao X, Abeysinghe R, Zheng F, Schulz PE; Alzheimer’s Disease Neuroimaging Initiative; Cui L. Hao X, et al. BMC Med Inform Decis Mak. 2024 Apr 19;24(Suppl 3):103. doi: 10.1186/s12911-024-02500-8. BMC Med Inform Decis Mak. 2024. PMID: 38641585 Free PMC article.
RESULTS: The data dictionaries downloaded on November 23, 2021 contain 1,195 data elements in NACC, 13,918 in ADNI, and 27,213 in NIH CDE Repository. Data element preprocessing reduced the numbers of NACC and ADNI data elements for mapping to 1,099 and 7,584 respect …
RESULTS: The data dictionaries downloaded on November 23, 2021 contain 1,195 data elements in NACC, 13,918 in ADNI, and 27,213 in NIH …
Improving Regression Analysis with Imputation in a Longitudinal Study of Alzheimer's Disease.
Chandrasekaran G, Xie SX; Alzheimer’s Disease Neuroimaging Initiative. Chandrasekaran G, et al. J Alzheimers Dis. 2024 Apr 17. doi: 10.3233/JAD-231047. Online ahead of print. J Alzheimers Dis. 2024. PMID: 38640151
METHODS: We studied 1,063 subjects in ADNI with mild cognitive impairment. Longitudinal ADAS-Cog 13 scores were modeled with a linear mixed-effects model with baseline clinical and demographic characteristics as predictors. ...CONCLUSIONS: Our study demonstrates the import …
METHODS: We studied 1,063 subjects in ADNI with mild cognitive impairment. Longitudinal ADAS-Cog 13 scores were modeled with a linear …
Joint transformer architecture in brain 3D MRI classification: its application in Alzheimer's disease classification.
Alp S, Akan T, Bhuiyan MS, Disbrow EA, Conrad SA, Vanchiere JA, Kevil CG, Bhuiyan MAN. Alp S, et al. Sci Rep. 2024 Apr 18;14(1):8996. doi: 10.1038/s41598-024-59578-3. Sci Rep. 2024. PMID: 38637671 Free PMC article.
ViT was utilized to extract features from MRIs, map them to a feature sequence, perform sequence modeling to maintain interdependencies, and classify features using a time series transformer. The proposed model was evaluated using ADNI T1-weighted MRIs for binary and multi …
ViT was utilized to extract features from MRIs, map them to a feature sequence, perform sequence modeling to maintain interdependencies, and …
Impact of APOE-ε alleles on brain structure and cognitive function in healthy older adults: A VBM and DTI replication study.
Lacey C, Paterson T, Gawryluk JR; Alzheimer’s Disease Neuroimaging Initiative. Lacey C, et al. PLoS One. 2024 Apr 18;19(4):e0292576. doi: 10.1371/journal.pone.0292576. eCollection 2024. PLoS One. 2024. PMID: 38635499 Free PMC article.
Baseline MRI, DTI and cognitive composite scores for memory (ADNI-Mem) and executive function (ADNI-EF) were acquired from 116 healthy controls. ...
Baseline MRI, DTI and cognitive composite scores for memory (ADNI-Mem) and executive function (ADNI-EF) were acquired from 116 …
Growth-Associated Protein 43 and Tensor-Based Morphometry Indices in Mild Cognitive Impairment.
Seyedmirzaei H, Salmannezhad A, Ashayeri H, Shushtari A, Farazinia B, Heidari MM, Momayezi A, Shaki Baher S. Seyedmirzaei H, et al. Neuroinformatics. 2024 Apr 17. doi: 10.1007/s12021-024-09663-9. Online ahead of print. Neuroinformatics. 2024. PMID: 38630411
We included MCI and cognitively normal (CN) people with available baseline and follow-up cerebrospinal fluid (CSF) GAP-43 and TBM findings from the ADNI database. We assessed the difference between the two groups and correlations in each group at each time point. ...
We included MCI and cognitively normal (CN) people with available baseline and follow-up cerebrospinal fluid (CSF) GAP-43 and TBM findings f …
Improved Correlation of 18F-Flortaucipir PET SUVRs and Clinical Stages in the Alzheimer Disease Continuum with the MUBADA/PERSI-Based Analysis.
Ikari Y, Akamatsu G, Matsumoto K, Yamane T, Senda M, Fukuchi K; AMED Preclinical AD Study Investigators, and Alzheimer’s Disease Neuroimaging Initiative Investigators. Ikari Y, et al. J Nucl Med Technol. 2024 Apr 16:jnmt.123.267113. doi: 10.2967/jnmt.123.267113. Online ahead of print. J Nucl Med Technol. 2024. PMID: 38627012
Cost-Sensitive Weighted Contrastive Learning Based on Graph Convolutional Networks for Imbalanced Alzheimer's Disease Staging.
Hu Y, Wang J, Zhu H, Li J, Shi J. Hu Y, et al. IEEE Trans Med Imaging. 2024 Apr 16;PP. doi: 10.1109/TMI.2024.3389747. Online ahead of print. IEEE Trans Med Imaging. 2024. PMID: 38625767
The proposed CSWCL-GCN is evaluated on 720 subjects (including 184 NCs, 40 SMC patients, 208 EMCI patients, 172 LMCI patients and 116 AD patients) from the ADNI (Alzheimer's Disease Neuroimaging Initiative). Experimental results show that the proposed CSWCL-GCN outperforms …
The proposed CSWCL-GCN is evaluated on 720 subjects (including 184 NCs, 40 SMC patients, 208 EMCI patients, 172 LMCI patients and 116 AD pat …
Differences of individual gray matter networks between MCI patients who converted to AD within 3 Years and nonconverters.
Zhou B, Zhao Y, Wu X. Zhou B, et al. Heliyon. 2024 Mar 29;10(7):e28874. doi: 10.1016/j.heliyon.2024.e28874. eCollection 2024 Apr 15. Heliyon. 2024. PMID: 38623255 Free PMC article.
MATERIALS AND METHODS: Data from 461 MCI patients (180 MCI-C and 281 MCI-NC) were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI). For each subject, a GM network was constructed using 3D-T1 imaging and the Kullback-Leibler divergence method. ...
MATERIALS AND METHODS: Data from 461 MCI patients (180 MCI-C and 281 MCI-NC) were obtained from the Alzheimer's Disease Neuroimaging Initiat …
2,956 results