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A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss.
Cohen RM, Rezai-Zadeh K, Weitz TM, Rentsendorj A, Gate D, Spivak I, Bholat Y, Vasilevko V, Glabe CG, Breunig JJ, Rakic P, Davtyan H, Agadjanyan MG, Kepe V, Barrio JR, Bannykh S, Szekely CA, Pechnick RN, Town T. Cohen RM, et al. Among authors: agadjanyan mg. J Neurosci. 2013 Apr 10;33(15):6245-56. doi: 10.1523/JNEUROSCI.3672-12.2013. J Neurosci. 2013. PMID: 23575824 Free PMC article.
MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice.
Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Kazarian K, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Davtyan H, et al. Among authors: agadjanyan mg. Vaccine. 2017 Apr 11;35(16):2015-2024. doi: 10.1016/j.vaccine.2017.03.020. Epub 2017 Mar 18. Vaccine. 2017. PMID: 28320590 Free PMC article.
81 results