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Repair of topoisomerase I-mediated DNA damage.
Pommier Y, Barcelo JM, Rao VA, Sordet O, Jobson AG, Thibaut L, Miao ZH, Seiler JA, Zhang H, Marchand C, Agama K, Nitiss JL, Redon C. Pommier Y, et al. Among authors: agama k. Prog Nucleic Acid Res Mol Biol. 2006;81:179-229. doi: 10.1016/S0079-6603(06)81005-6. Prog Nucleic Acid Res Mol Biol. 2006. PMID: 16891172 Free PMC article. Review.
Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity.
Antony S, Agama KK, Miao ZH, Hollingshead M, Holbeck SL, Wright MH, Varticovski L, Nagarajan M, Morrell A, Cushman M, Pommier Y. Antony S, et al. Among authors: agama kk. Mol Pharmacol. 2006 Sep;70(3):1109-20. doi: 10.1124/mol.106.024372. Epub 2006 Jun 23. Mol Pharmacol. 2006. PMID: 16798938
84 results