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Buchu (Agathosma betulina and A. crenulata): Rightfully Forgotten or Underutilized?
Brendler T, Abdel-Tawab M. Brendler T, et al. Front Pharmacol. 2022 Feb 7;13:813142. doi: 10.3389/fphar.2022.813142. eCollection 2022. Front Pharmacol. 2022. PMID: 35197854 Free PMC article. Review.
Today, the term buchu refers to the two species in commerce, Agathosma betulina (P.J.Bergius) Pillans and Agathosma crenulata (L.) Pillans (Rutaceae). ...Moderate antioxidant activity was determined for methanol:dichlormethane extracts of A. betulin …
Today, the term buchu refers to the two species in commerce, Agathosma betulina (P.J.Bergius) Pillans and Agathosma cre …
'Buchu' -Agathosma betulina and Agathosma crenulata (Rutaceae): a review.
Moolla A, Viljoen AM. Moolla A, et al. J Ethnopharmacol. 2008 Oct 28;119(3):413-9. doi: 10.1016/j.jep.2008.07.036. Epub 2008 Aug 3. J Ethnopharmacol. 2008. PMID: 18725278 Review.
South Africa has offered the world two indigenous aromatic plants from which commercially important natural products have been developed: Pelargonium graveolens (and its hybrids) the source of geranium oil and Agathosma betulina, from which 'Buchu' oil is produced. …
South Africa has offered the world two indigenous aromatic plants from which commercially important natural products have been developed: Pe …
Safety and efficacy of a feed additive consisting of an essential oil from the leaves of Agathosma betulina (P.J. Bergius) Pillans (buchu leaf oil) for use in all animal species (FEFANA asbl).
EFSA Panel on Additives, Products or Substances used in Animal Feed (FEEDAP); Bampidis V, Azimonti G, Bastos ML, Christensen H, Fašmon Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Brantom P, Chesson A, Westendorf J, Manini P, Pizzo F, Dusemund B. EFSA Panel on Additives, Products or Substances used in Animal Feed (FEEDAP), et al. EFSA J. 2022 Mar 8;20(3):e07160. doi: 10.2903/j.efsa.2022.7160. eCollection 2022 Mar. EFSA J. 2022. PMID: 35281638 Free PMC article.
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the leaves of Agathosma betulina (P.J. …
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was as …
Density functional theory and molecular dynamics simulation-based bioprospection of Agathosma betulina essential oil metabolites against protein tyrosine phosphatase 1B for interventive antidiabetic therapy.
Adedirin O, Abdulsalam RA, Nasir-Naeem KO, Oke AA, Jubril AO, Sabiu S. Adedirin O, et al. Heliyon. 2025 Jan 24;11(3):e42239. doi: 10.1016/j.heliyon.2025.e42239. eCollection 2025 Feb 15. Heliyon. 2025. PMID: 39991230 Free PMC article.
This study bioprospects the antidiabetic potential of metabolites in Agathosma betulina (Buchu) essential oil through computational analysis of their ability to inhibit protein tyrosine phosphatase 1B (PTP1B), a therapeutic diabetes target. ...
This study bioprospects the antidiabetic potential of metabolites in Agathosma betulina (Buchu) essential oil through computat …
Buchu (Agathosma betulina and A. crenulata, Rutaceae) essential oils: their pharmacological action on guinea-pig ileum and antimicrobial activity on microorganisms.
Lis-Balchin M, Hart S, Simpson E. Lis-Balchin M, et al. J Pharm Pharmacol. 2001 Apr;53(4):579-82. doi: 10.1211/0022357011775703. J Pharm Pharmacol. 2001. PMID: 11341377
The mode of action of essential oils from two buchu species (Agathosma betulina and A. crenulata, Rutaceae) from the Cape region of South Africa has been studied on smooth muscle in-vitro using guinea-pig ileum. ...In the presence of the phosphodiesterase inh …
The mode of action of essential oils from two buchu species (Agathosma betulina and A. crenulata, Rutaceae) from the Ca …
First Report of the Root-Knot Nematode Meloidogyne javanica on Buchu (Agathosma betulina) in South Africa.
Malan AP, Knoetze R, Hugo HJ. Malan AP, et al. Plant Dis. 2004 May;88(5):574. doi: 10.1094/PDIS.2004.88.5.574A. Plant Dis. 2004. PMID: 30812672 Free article.
Agathosma betulina, commonly known as buchu, has been used for centuries by the indigenous people of South Africa for medicinal purposes. ...To our knowledge, this is the first report of M. javanica causing extensive galling on the roots of Agathosma betul …
Agathosma betulina, commonly known as buchu, has been used for centuries by the indigenous people of South Africa for medicina …
Geographic Influence on Secondary Metabolite Profiles in Leaves of the Endemic Agathosma betulina (P.J. Bergius) Pillans. in the Western Cape Province, South Africa.
Mnisi NH, Gunununu RP, Dukashe L, Makgato MJ, Mulidzi AR, Bvenura C, Mashabela NM. Mnisi NH, et al. Int J Mol Sci. 2026 May 16;27(10):4486. doi: 10.3390/ijms27104486. Int J Mol Sci. 2026. PMID: 42196464 Free PMC article.
The role of medicinal plants in primary healthcare and livelihoods around the world is both ancient and well-documented. Agathosma betulina (P.J. Bergius) Pillans, commonly known as 'buchu', has long been utilised in traditional medicine as a household remedy for va …
The role of medicinal plants in primary healthcare and livelihoods around the world is both ancient and well-documented. Agathosma …
Phytophthora taxa associated with cultivated Agathosma, with emphasis on the P. citricola complex and P. capensis sp. nov.
Bezuidenhout CM, Denman S, Kirk SA, Botha WJ, Mostert L, McLeod A. Bezuidenhout CM, et al. Persoonia. 2010 Dec;25:32-49. doi: 10.3767/003158510X538371. Epub 2010 Oct 29. Persoonia. 2010. PMID: 21339965 Free PMC article.
Agathosma species, which are indigenous to South Africa, are also cultivated for commercial use. ...The pathogenicity of representative isolates of the taxa from Agathosma was tested on A. betulina seedlings. The putative novel species, P. taxon emzansi, and …
Agathosma species, which are indigenous to South Africa, are also cultivated for commercial use. ...The pathogenicity of representati …
Micro-particle-induced X-ray emission mapping of elemental distribution in roots of a Mediterranean-type sclerophyll, Agathosma betulina (Berg.) Pillans, colonized by Cryptococcus laurentii.
Cloete KJ, Przybylowicz WJ, Mesjasz-Przybylowicz J, Barnabas AD, Valentine AJ, Botha A. Cloete KJ, et al. Plant Cell Environ. 2010 Jun;33(6):1005-15. doi: 10.1111/j.1365-3040.2010.02122.x. Epub 2010 Jan 29. Plant Cell Environ. 2010. PMID: 20132522 Free article.
This study, therefore, focused on quantitative elemental distribution within the roots of a medicinal sclerophyll, Agathosma betulina (Berg.) Pillans, grown under nutrient-poor conditions, and colonized by Cryptococcus laurentii. Micro-particle-induced X-ray emissio …
This study, therefore, focused on quantitative elemental distribution within the roots of a medicinal sclerophyll, Agathosma betul …
Evidence of symbiosis between the soil yeast Cryptococcus laurentii and a sclerophyllous medicinal shrub, Agathosma betulina (Berg.) Pillans.
Cloete KJ, Valentine AJ, Stander MA, Blomerus LM, Botha A. Cloete KJ, et al. Microb Ecol. 2009 May;57(4):624-32. doi: 10.1007/s00248-008-9457-9. Epub 2008 Oct 29. Microb Ecol. 2009. PMID: 18958514
The interaction between a common soil yeast, Cryptococcus laurentii, and a slow-growing medicinal plant adapted to low-nutrient soils, Agathosma betulina (Berg.) Pillans, was studied. C. laurentii CAB 578 was isolated from the rhizosphere of wild A. betulina, …
The interaction between a common soil yeast, Cryptococcus laurentii, and a slow-growing medicinal plant adapted to low-nutrient soils, Ag …
15 results