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Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
Sung B, Pandey MK, Aggarwal BB. Sung B, et al. Among authors: aggarwal bb. Mol Pharmacol. 2007 Jun;71(6):1703-14. doi: 10.1124/mol.107.034512. Epub 2007 Mar 26. Mol Pharmacol. 2007. PMID: 17387141
Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis.
Sung B, Pandey MK, Ahn KS, Yi T, Chaturvedi MM, Liu M, Aggarwal BB. Sung B, et al. Among authors: aggarwal bb. Blood. 2008 May 15;111(10):4880-91. doi: 10.1182/blood-2007-10-117994. Epub 2008 Mar 18. Blood. 2008. PMID: 18349320 Free PMC article.
658 results