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Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.
Goel A, Aggarwal BB. Goel A, et al. Among authors: aggarwal bb. Nutr Cancer. 2010;62(7):919-30. doi: 10.1080/01635581.2010.509835. Nutr Cancer. 2010. PMID: 20924967 Review.
Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.
Prakobwong S, Khoontawad J, Yongvanit P, Pairojkul C, Hiraku Y, Sithithaworn P, Pinlaor P, Aggarwal BB, Pinlaor S. Prakobwong S, et al. Among authors: aggarwal bb. Int J Cancer. 2011 Jul 1;129(1):88-100. doi: 10.1002/ijc.25656. Epub 2010 Nov 3. Int J Cancer. 2011. PMID: 20824699
Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells.
Kamat AM, Sethi G, Aggarwal BB. Kamat AM, et al. Among authors: aggarwal bb. Mol Cancer Ther. 2007 Mar;6(3):1022-30. doi: 10.1158/1535-7163.MCT-06-0545. Mol Cancer Ther. 2007. PMID: 17363495
Chemosensitization and radiosensitization of tumors by plant polyphenols.
Garg AK, Buchholz TA, Aggarwal BB. Garg AK, et al. Among authors: aggarwal bb. Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1630-47. doi: 10.1089/ars.2005.7.1630. Antioxid Redox Signal. 2005. PMID: 16356126 Review.
Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.
Yan C, Jamaluddin MS, Aggarwal B, Myers J, Boyd DD. Yan C, et al. Among authors: aggarwal b. Mol Cancer Ther. 2005 Feb;4(2):233-41. Mol Cancer Ther. 2005. PMID: 15713895
Acquisition of cellular resistance to 9-nitro-camptothecin correlates with suppression of transcription factor NF-kappa B activation and potentiation of cytotoxicity by tumor necrosis factor in human histiocytic lymphoma U-937 cells.
Singh S, Raju U, Mendoza J, Pantazis P, Aggarwal BB. Singh S, et al. Among authors: aggarwal bb. Anticancer Drugs. 1998 Sep;9(8):703-14. doi: 10.1097/00001813-199809000-00006. Anticancer Drugs. 1998. PMID: 9823429
Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines.
Mehta K, Pantazis P, McQueen T, Aggarwal BB. Mehta K, et al. Among authors: aggarwal bb. Anticancer Drugs. 1997 Jun;8(5):470-81. doi: 10.1097/00001813-199706000-00010. Anticancer Drugs. 1997. PMID: 9215611
{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.
Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, Dey S, Koca C, Yadav VR, Tong Z, Gelovani JG, Guha S, Krishnan S, Aggarwal BB. Kunnumakkara AB, et al. Among authors: aggarwal bb. Cancer Res. 2010 Nov 1;70(21):8695-705. doi: 10.1158/0008-5472.CAN-10-2318. Epub 2010 Sep 23. Cancer Res. 2010. PMID: 20864511 Free PMC article.
Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer.
Nair HB, Sung B, Yadav VR, Kannappan R, Chaturvedi MM, Aggarwal BB. Nair HB, et al. Among authors: aggarwal bb. Biochem Pharmacol. 2010 Dec 15;80(12):1833-43. doi: 10.1016/j.bcp.2010.07.021. Epub 2010 Jul 21. Biochem Pharmacol. 2010. PMID: 20654584 Free PMC article. Review.
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals.
Gupta SC, Kim JH, Prasad S, Aggarwal BB. Gupta SC, et al. Among authors: aggarwal bb. Cancer Metastasis Rev. 2010 Sep;29(3):405-34. doi: 10.1007/s10555-010-9235-2. Cancer Metastasis Rev. 2010. PMID: 20737283 Free PMC article. Review.
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