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Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.
Werninghaus K, Babiak A, Gross O, Hölscher C, Dietrich H, Agger EM, Mages J, Mocsai A, Schoenen H, Finger K, Nimmerjahn F, Brown GD, Kirschning C, Heit A, Andersen P, Wagner H, Ruland J, Lang R. Werninghaus K, et al. Among authors: agger em. J Exp Med. 2009 Jan 16;206(1):89-97. doi: 10.1084/jem.20081445. Epub 2009 Jan 12. J Exp Med. 2009. PMID: 19139169 Free PMC article.
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.
Schoenen H, Bodendorfer B, Hitchens K, Manzanero S, Werninghaus K, Nimmerjahn F, Agger EM, Stenger S, Andersen P, Ruland J, Brown GD, Wells C, Lang R. Schoenen H, et al. Among authors: agger em. J Immunol. 2010 Mar 15;184(6):2756-60. doi: 10.4049/jimmunol.0904013. Epub 2010 Feb 17. J Immunol. 2010. PMID: 20164423 Free PMC article.
99 results