Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2004 1
2014 1
2015 1
2019 1
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

4 results

Results by year

Filters applied: . Clear all
Page 1
Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation.
Itoua Maïga R, Cencic R, Chu J, Waller DD, Brown LE, Devine WG, Zhang W, Sebag M, Porco JA Jr, Pelletier J. Itoua Maïga R, et al. Sci Rep. 2019 Feb 4;9(1):1265. doi: 10.1038/s41598-018-37666-5. Sci Rep. 2019. PMID: 30718665 Free PMC article.
Here we explore the ability of synthetic derivatives of aglaiastatins and an aglaroxin derivative to target the translation process in vitro and in vivo and find the synthetic derivative oxo-aglaiastatin to possess such activity. Oxo-aglaiastatin inhibited translati …
Here we explore the ability of synthetic derivatives of aglaiastatins and an aglaroxin derivative to target the translation process in vitro …
Biomimetic kinetic resolution: highly enantio- and diastereoselective transfer hydrogenation of aglain ketones to access flavagline natural products.
Stone SD, Lajkiewicz NJ, Whitesell L, Hilmy A, Porco JA Jr. Stone SD, et al. J Am Chem Soc. 2015 Jan 14;137(1):525-30. doi: 10.1021/ja511728b. Epub 2014 Dec 29. J Am Chem Soc. 2015. PMID: 25514979 Free PMC article.
The methodology has been employed to synthesize and confirm the absolute stereochemistries of the pyrimidone rocaglamides (+)-aglaiastatin and (-)-aglaroxin C. Additionally, the enantiomers and racemate of each metabolite were assayed for inhibition of the heat-shock respo …
The methodology has been employed to synthesize and confirm the absolute stereochemistries of the pyrimidone rocaglamides (+)-aglaiastati …
Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata.
Ohse T, Ohba S, Yamamoto T, Koyano T, Umezawa K. Ohse T, et al. J Nat Prod. 1996 Jul;59(7):650-2. doi: 10.1021/np960346g. J Nat Prod. 1996. PMID: 8759160
In the course of screening for Ras function inhibitors, rocaglaol (1) and the related compounds, the known pyrimidinone (2) and the novel aglaiastatin (3), were isolated from a CHCI3 extract of the leaves of Aglaia odorata. The structure of 3 was elucidated as a novel cycl …
In the course of screening for Ras function inhibitors, rocaglaol (1) and the related compounds, the known pyrimidinone (2) and the novel …
Flavaglines: a group of efficient growth inhibitors block cell cycle progression and induce apoptosis in colorectal cancer cells.
Hausott B, Greger H, Marian B. Hausott B, et al. Int J Cancer. 2004 May 10;109(6):933-40. doi: 10.1002/ijc.20033. Int J Cancer. 2004. PMID: 15027128
To assess their suitability as chemotherapeutic drugs in colorectal cancer, their cytostatic effects and the underlying mechanisms of action were analyzed in colorectal tumor cell lines. Aglaiastatin was the most active flavagline, inhibiting growth and inducing apoptosis …
To assess their suitability as chemotherapeutic drugs in colorectal cancer, their cytostatic effects and the underlying mechanisms of action …